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European Journal of Nuclear Medicine and Molecular Imaging

Published in:

Open Access 01-03-2009

The potential of PET/MR for brain imaging

Author: Wolf-Dieter Heiss

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Special Issue 1/2009

Abstract

Introduction

The completion of an integrated PET/MR prototype system for brain imaging is the latest step in the evolution of positron emission tomography. Early images with this new imaging system demonstrate that high-resolution multiparametric studies can be combined without significant loss of performance of either imaging modality.

Objective

This new technology will make fusion of morphological and biological information much easier, yield real-time assessment of complementary variables and will provide dynamic information for kinetic modelling. Simultaneous acquisition of various metabolic and functional parameters may open new insights into the organization of the brain and its changes in disease.

Discussion

A new field may open up for molecular and cellular imaging, where new targets – e.g. angiogenesis, gene transfer, function and migration of transplanted cells – can be imaged in the morphological context and within a functional environment. This application might have a special impact on the translation of treatment concepts from experimental models into clinical application. If the added value of the hybrid system for diagnosis and treatment monitoring is established, a cost-effective PET/MR combination might attain wider clinical application.

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Title: The potential of PET/MR for brain imaging
Author: Wolf-Dieter Heiss
Publication date: 01-03-2009
Publisher: Springer-Verlag
Published in: European Journal of Nuclear Medicine and Molecular Imaging / Issue Special Issue 1/2009
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-008-0962-3

At a glance: The STEP trials

Springer Medicine

The potential of PET/MR for brain imaging

Abstract

Introduction

Objective

Discussion

At a glance: The STEP trials

Springer Medicine

Abstract

Introduction

Objective

Discussion

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