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Diabetologia
Published in: Diabetologia 4/2016

01-04-2016 | Letter

The pancreas in humans with and without diabetes

Author: Yoshifumi Saisho

Published in: Diabetologia | Issue 4/2016

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Excerpt

To the Editor: We read the paper by Campbell-Thompson et al with great interest [1]. In this study, they used relative pancreas weight (RPW; pancreas weight [g]/body weight [kg]), attempting to normalise the effects of age, ethnicity and body weight. As a result, RPW showed no association with age and was significantly reduced in patients with type 1 diabetes. There was no correlation between RPW and disease duration. …
Literature
1.
Campbell-Thompson ML, Kaddis JS, Wasserfall C et al (2016) The influence of type 1 diabetes on pancreatic weight. Diabetologia 59:217–221CrossRefPubMed
2.
Saisho Y, Butler AE, Meier JJ et al (2007) Pancreas volumes in humans from birth to age one hundred taking into account sex, obesity, and presence of type-2 diabetes. Clin Anat 20:933–942CrossRefPubMedPubMedCentral
3.
Saisho Y (2014) Pancreas volume with obesity in Asians: comparison with whites. Pancreas 43:657–659CrossRefPubMed
4.
Kou K, Saisho Y, Jinzaki M, Itoh H (2014) Relationship between body mass index and pancreas volume in Japanese adults. JOP: J Pancreas 15:626–627
5.
Saisho Y, Butler AE, Manesso E, Elashoff D, Rizza RA, Butler PC (2013) β-cell mass and turnover in humans: effects of obesity and aging. Diabetes Care 36:111–117CrossRefPubMedPubMedCentral
6.
Atkinson MA, von Herrath M, Powers AC, Clare-Salzler M (2015) Current concepts on the pathogenesis of type 1 diabetes—considerations for attempts to prevent and reverse the disease. Diabetes Care 38:979–988CrossRefPubMed
7.
DeFronzo RA, Eldor R, Abdul-Ghani M (2013) Pathophysiologic approach to therapy in patients with newly diagnosed type 2 diabetes. Diabetes Care 36(Suppl 2):S127–S138CrossRefPubMedPubMedCentral
Metadata
Title
The pancreas in humans with and without diabetes
Author
Yoshifumi Saisho
Publication date
01-04-2016
Publisher
Springer Berlin Heidelberg
Published in
Diabetologia / Issue 4/2016
Print ISSN: 0012-186X
Electronic ISSN: 1432-0428
DOI
https://doi.org/10.1007/s00125-016-3881-z

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