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Rheumatology International
Published in: Rheumatology International 12/2013

Open Access 01-12-2013 | Short Communication

The osteocalcin gene rs1800247 polymorphism in Kashubian population

Authors: Krzysztof Specjalski, Maria Porzezińska, Alicja Siemińska, Jan M. Słomiński, Ewa Jassem

Published in: Rheumatology International | Issue 12/2013

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Abstract

Osteocalcin is the most important noncollagenous protein component of the bone. Polymorphisms of osteocalcin gene were reported to be associated with bone mineral density. However, this relation was only confirmed in some populations. In this study presence of C/T polymorphism in osteocalcin gene (rs1800247) was determined in Kashubian population (northern Poland). The frequencies of variants were CC 9 %, TC 31 %, and TT 60 %, with no significant differences between genders. The genotypes were in Hardy–Weinberg equilibrium.
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Metadata
Title
The osteocalcin gene rs1800247 polymorphism in Kashubian population
Authors
Krzysztof Specjalski
Maria Porzezińska
Alicja Siemińska
Jan M. Słomiński
Ewa Jassem
Publication date
01-12-2013
Publisher
Springer Berlin Heidelberg
Published in
Rheumatology International / Issue 12/2013
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-012-2575-1

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