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Published in: Current Gastroenterology Reports 4/2010

01-08-2010

The Noncolonic Microbiome: Does it Really Matter?

Authors: R. Daniel Lawson, Walter J. Coyle

Published in: Current Gastroenterology Reports | Issue 4/2010

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Abstract

About 100 trillion microorganisms compose the microbiome of the gastrointestinal tract and are predominantly found within the colon. Until recently, few bacteria were thought to inhabit the normal healthy esophagus and stomach. However, contemporary studies using molecular techniques have contradicted these assumptions. In this review, we summarize the pertinent findings of these studies that demonstrate established, complex mixed-microbial communities within the foregut in both health and disease. These studies contribute to improved understanding of interactions between the host immunity and the microbiome that may ultimately allow for novel therapeutic targets.
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Metadata
Title
The Noncolonic Microbiome: Does it Really Matter?
Authors
R. Daniel Lawson
Walter J. Coyle
Publication date
01-08-2010
Publisher
Current Science Inc.
Published in
Current Gastroenterology Reports / Issue 4/2010
Print ISSN: 1522-8037
Electronic ISSN: 1534-312X
DOI
https://doi.org/10.1007/s11894-010-0111-6

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