Top

Published in:

01-07-2018 | Original Article

The impacts of yoghurt butter oil on rat testicular morphology and sexual hormones in a 150-day study

Authors: Mohammadmehdi Hassanzadeh-Taheri, Farnaz Jahani, Mahsa Hassanzadeh-Taheri, Mohammadreza Doostabadi, Hamidreza Doostabadi, Mehran Hosseini

Published in: Comparative Clinical Pathology | Issue 4/2018

Abstract

The oil derived from traditional produced yoghurt has received much attention over the last two decades. While a high-fat diet (HFD) is assumed to be related to reproductive impairments, fermented dairy products are believed to have positive effects on the regulation of HFD-induced male reproductive damage. The reproductive effects of sheep’s yoghurt butter oil (SYBO) have never been studied yet. The current study was to seek for the scientific evidence to determine SYBO effects on male rat reproductive system. In the present study, male Wistar rats were treated by standard diet or standard diet supplemented with 10% (w/w) or 20% of SYBO for 150 days. Treatment of animals with SYBO (at the both concentrations) did not cause significant alterations in the body weight, testicular morphology and its weight, circulatory concentrations of testosterone, and follicle-stimulating hormone (FSH). However, plasma levels of estradiol and luteinizing hormone (LH) significantly declined (p < 0.05) in 10–20% SYBO-treated rats. The evidence from this study supports that high-fat diet made by sheep’s yoghurt butter oil had not devastating effects on rat reproductive system even though in long-term period.

Attaman JA, Toth TL, Furtado J, Campos H, Hauser R, Chavarro JE (2012) Dietary fat and semen quality among men attending a fertility clinic. Hum Reprod 27(5):1466–1474. https://doi.org/10.1093/humrep/des065 CrossRefPubMedPubMedCentral

Barone R, Macaluso F, Catanese P, Marino Gammazza A, Rizzuto L, Marozzi P, Lo Giudice G, Stampone T, Cappello F, Morici G, Zummo G, Farina F, di Felice V (2013) Endurance exercise and conjugated linoleic acid (CLA) supplementation up-regulate CYP17A1 and stimulate testosterone biosynthesis. PLoS One 8(11):e79686. https://doi.org/10.1371/journal.pone.0079686 CrossRefPubMedPubMedCentral

Brook CG, Marshall NJ (2001) Essential endocrinology. Wiley-Blackwell, London

Campos-Silva P, Furriel A, Costa WS, Sampaio FJ, Gregório BM (2015) Metabolic and testicular effects of the long-term administration of different high-fat diets in adult rats. Int Braz J Urol 41(3):569–575. https://doi.org/10.1590/S1677-5538.IBJU.2014.0244 CrossRefPubMedPubMedCentral

Carrillo B, Collado P, Díaz F, Chowen JA, Pérez-Izquierdo MÁ, Pinos H (2017) Physiological and brain alterations produced by high-fat diet in male and female rats can be modulated by increased levels of estradiol during critical periods of development. Nutr Neurosci:1–11. https://doi.org/10.1080/1028415X.2017.1349574

Chaturvedi P, Moseki P, Mazunga K (2016) Effects of used sunflower oil and ghee (clarified butter) on lipid profile and antioxidants in SD rats. EJBPS 3(10):59–64

Choi J, Smitz J (2014) Luteinizing hormone and human chorionic gonadotropin: Origins of difference. Mol Cell Endocrinol 5(383):203–213. https://doi.org/10.1016/j.mce.2013.12.009 CrossRef

Cui X-Y, Li Y-Y, Liu R-R, Zhao G-P, Zheng M-Q, Li Q-H, Wen J (2016) Follicle-stimulating hormone increases the intramuscular fat content and expression of lipid biosynthesis genes in chicken breast muscle. J Zhejiang Univ Sci B 17(4):303–310. https://doi.org/10.1631/jzus.B1500139 CrossRefPubMedCentral

Di Felice V, Macaluso F, Montalbano A, Gammazza AM (2007) Effects of conjugated linoleic acid and endurance training on peripheral blood and bone marrow of trained mice. J Strength Cond Res 21(1):193–198. https://doi.org/10.1519/R-18955.1 CrossRefPubMed

Ezi S, Hosseini M, Hassanzadeh-Taheri M, Jahani F, Afshar M, Hassanzadeh-Taheri M (2016) Effects of Tail fat enriched diet on male Wistar rat reproductive system. J Birjand Univ Med Sci 23(1):1–10

Fındık O, Andiç S (2017) Some chemical and microbiological properties of the butter and the butter oil produced from the same raw material. LWT - Food Sci Technol 86:233–239. https://doi.org/10.1019/j.lwt.201.08.002 CrossRef

Gaskins AJ, Chavarro JE (2017) Diet and fertility: a review. Am J Obstet Gynecol S0002-9378(17):30945–30946. https://doi.org/10.1016/j.ajog.2017.08.010 CrossRef

Hassanzadeh-Taheri M, Hassanzadeh-Taheri M, Jahani F, Hosseini M (2018) Effects of yoghurt butter oils on rat plasma lipids, haematology and liver histology parameters in a 150-day study. Int J Dairy Technol 71:140–148. https://doi.org/10.1111/1471-0307.12419 CrossRef

Hosseini M, Naghan PA, Jafari AM, Yousefifard M, Taslimi S, Khodadad K, Mohammadi F, Sadr M, Rezaei M, Mortaz E, Masjedi MR (2014) Nutrition and lung cancer: a case control study in Iran. BMC Cancer 14(860). https://doi.org/10.1186/1471-2407-14-860

Hugenholtz J, Smid E (2002) Nutraceutical production with food-grade microorganisms. Curr Opin Biotechnol 13(5):497–507. https://doi.org/10.1016/S0958-1669(02)00367-1 CrossRefPubMed

Hurtado de Catalfo GE, de Alaniz M, Marra CA (2009) Influence of commercial dietary oils on lipid composition and testosterone production in interstitial cells isolated from rat testis. Lipids 44(4):345–357. https://doi.org/10.1007/s11745-008-3277-z CrossRefPubMed

Lei K, Li Y-L, Wang Y, Wen J, Wu H-Z, Yu D-Y, Li W-F (2015) Effect of dietary supplementation of Bacillus subtilis B10 on biochemical and molecular parameters in the serum and liver of high-fat diet-induced obese mice. J Zhejiang Univ Sci B 16(6):487–495. https://doi.org/10.1631/jzus.B1400342 CrossRefPubMedPubMedCentral

Martínez-Martos JM, Arrazola M, Mayas MD, Carrera-González MP, García MJ, Ramírez-Expósito MJ (2011) Diet-induced hypercholesterolemia impaired testicular steroidogenesis in mice through the renin–angiotensin system. Gen Comp Endocrinol 173(1):15–19. https://doi.org/10.1016/j.ygcen.2011.04.015 CrossRefPubMed

Mumford SL, Chavarro JE, Zhang C, Perkins NJ, Sjaarda LA, Pollack AZ, Schliep KC, Michels KA, Zarek SM, Plowden TC, Radin RG, Messer LC, Frankel RA, Wactawski-Wende J (2016) Dietary fat intake and reproductive hormone concentrations and ovulation in regularly menstruating women. Am J Clin Nutr 103(3):868–877. https://doi.org/10.3945/ajcn115119321 CrossRefPubMedPubMedCentral

Olivares A, Méndez JP, Zambrano E, Cárdenas M, Tovar A, Perera-Marín G, Ulloa-Aguirre A (2010) Reproductive axis function and gonadotropin microheterogeneity in a male rat model of diet-induced obesity. Gen Comp Endocrinol 166(2):356–364. https://doi.org/10.1016/j.ygcen.2009.12.007 CrossRefPubMed

Parvez S, Malik KA, Ah Kang S, Kim HY (2006) Probiotics and their fermented food products are beneficial for health. J Appl Microbiol 100(6):1171–1185. https://doi.org/10.1111/j.1365-2672.2006.02963.x CrossRefPubMed

Prentice AM (2014) Dairy products in global public health. Am J Clin Nutr 99(5 suppl):1212S–1216S. https://doi.org/10.3945/ajcn.113.073437 CrossRefPubMed

Scaia MF, Volonteri MC, Czuchlej SC, Ceballos NR (2015) Effect of estradiol on apoptosis, proliferation and steroidogenic enzymes in the testes of the toad Rhinella arenarum (Amphibia, Anura). Gen Comp Endocrinol 15(221):244–254. https://doi.org/10.1016/j.ygcen.2014.12.016 CrossRef

Segarra A et al (2002) Effects of dietary supplementation with fish oil, lard, or coconut oil on oxytocinase activity in the testis of mice. Arch Androl 48(3):233–236. https://doi.org/10.1080/01485010252869333 CrossRefPubMed

Şenel E, Atamer M, Öztekin FŞ (2011) The oxidative and lipolytic stability of Yayık butter produced from different species of mammals milk (cow, sheep, goat) yoghurt. Food Chem 127(1):333–339. https://doi.org/10.1016/j.foodchem.2011.01.012 CrossRef

Serafeimidou A, Zlatanos S, Laskaridis K, Sagredos A (2012) Chemical characteristics, fatty acid composition and conjugated linoleic acid (CLA) content of traditional Greek yogurts. Food Chem 134(4):1839–1846. https://doi.org/10.1016/j.foodchem.2012.03.102 CrossRefPubMed

Serki E, Vazifeshenas Darmiyan K, Ezi S, Bayat J, Shahamat F, Ghiravani Z, Hosseini M (2016) Effects of colostrum on sperm parameters, sex hormones and testes histopathological changes in diabetic rats. JMUMS 26(141):83–94

Thoma ME, McLain AC, Louis JF, King RB, Trumble AC, Sundaram R, Louis GMB (2013) Prevalence of infertility in the United States as estimated by the current duration approach and a traditional constructed approach. Fertil Steril 99(5):1324–1331. https://doi.org/10.1016/j.fertnstert.2012.11.037 CrossRefPubMedPubMedCentral

Wahlig JL, Bales ES, Jackman MR, Johnson GC, McManaman JL, MacLean PS (2012) Impact of high-fat diet and obesity on energy balance and fuel utilization during the metabolic challenge of lactation Obesity. Obesity (Silver Spring) 20(1):65–75. https://doi.org/10.1038/oby.2011.196 CrossRef

Walczak-Jędrzejowska R, Marchlewska K, Oszukowska E, Filipiak E, Słowikowska-Hilczer J, Kula K (2013) Estradiol and testosterone inhibit rat seminiferous tubule development in a hormone-specific way. Reprod Biol 13(3):243–250. https://doi.org/10.1016/j.repbio.2013.07.005 CrossRefPubMed

Yang B et al (2017) Bacterial conjugated linoleic acid production and their applications. Prog Lipid Res 68:26–36. https://doi.org/10.1016/j.plipres.2017.09.002 CrossRefPubMed

Title: The impacts of yoghurt butter oil on rat testicular morphology and sexual hormones in a 150-day study
Authors: Mohammadmehdi Hassanzadeh-Taheri
Farnaz Jahani
Mahsa Hassanzadeh-Taheri
Mohammadreza Doostabadi
Hamidreza Doostabadi
Mehran Hosseini
Publication date: 01-07-2018
Publisher: Springer London
Published in: Comparative Clinical Pathology / Issue 4/2018
Print ISSN: 1618-5641
Electronic ISSN: 1618-565X
DOI: https://doi.org/10.1007/s00580-018-2688-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The impacts of yoghurt butter oil on rat testicular morphology and sexual hormones in a 150-day study

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 4/2018

Correction to: Perturbations of erythrocyte membrane integrity by subchronic low-level lead exposure in New Zealand white rabbits

A novel pathology of a mediastinal neoplasm

Haemocytomorphometric variation in different ages of Japanese quail, Coturnix coturnix japonica (Temminck and Schlegel, 1849)

Antibiotic resistance profile of Trueperella pyogenes isolated from three cases of goat kids affected by sever cardiopulmonary disease

Sero-epidemiological study of peste des petits ruminants in small ruminants in Amahara region, Ethiopia

Effect of age, breed and sex on haematological and blood biochemical parameters in helmeted guinea fowl (Numida meleagris)