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Comparative Clinical Pathology
Published in: Comparative Clinical Pathology 4/2018

01-07-2018 | Original Article

Sero-epidemiological study of peste des petits ruminants in small ruminants in Amahara region, Ethiopia

Authors: Tsegaw Fentie, Yechale Teshome, Birhanu Ayele, Wassie Molla, Nigusie Fenta, Seleshe Nigatu, Ashenafe Assefa, Samson Leta

Published in: Comparative Clinical Pathology | Issue 4/2018

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Abstract

Peste des petits ruminants (PPR) is an acute, highly contagious, and economically important transboundary viral disease of sheep and goats. It is among the major infectious diseases that affect the production and productivity of small ruminants in Ethiopia. Cross-sectional and retrospective studies were undertaken to estimate the sero-prevalence, risk factors, and distribution of PPR in Amhara region. A total of 672 (329 sheep and 343 goats) sera were collected from 30 kebeles in 10 districts. Of the 672 sheep and goat sera samples tested using c-ELISA, 123 were positive for PPR antibodies, with the overall prevalence of 18.30% (95%CI 15.37, 21.24). The sero-prevalence of PPR was 21.57% (95%CI 17.15, 25.86) in goats and 14.89% (95%CI 10.96–18.65) in sheep. The variation of sero-prevalence among study zones was statistically significant (p < 0.05). The highest sero-prevalence was reported in Awi zone (55.34%) followed by South Gondar (15.89%), North Gondar (13.64%), East Gojjam (7.93%), and West Gojjam (6.62%) zones. Among host- and environment-related risk factors, species, sex, agro-ecology, and location of the study were significantly associated with PPR sero-positivity. The analysis of 5-year retrospective data (2010–2014) revealed high occurrence of PPR in the Amhara region with a total occurrence of 63 outbreaks (3978 cases and 919 deaths). In conclusion, the study revealed that PPR is an important and widely distributed disease of small ruminants in Amhara region. Appropriate control strategy including regular surveillance and vaccination is recommended to mitigate the challenge of PPR.
Literature
Abraham G, Sintayehu A, Libeau G, Albina E, Roger F, Laekemariam Y, Abayneh D, Awoke KM (2005) Antibody seroprevalences against peste des petits ruminants (PPR) virus in camels, cattle, goats and sheep in Ethiopia. Prev Vet Med 70:51–57CrossRefPubMed
Abubakar M, Arshed MJ, Hussain M, Ali Q (2011) Evidence of peste des petits ruminants in serology of sheep and goats from Sindh, Pakistan. Transbound Emerg Dis 58:152–156CrossRefPubMed
Alemu, B. 2014. Epidemiology and identification of peste des petits ruminants (PPR) virus circulating in small ruminants of eastern Amhara region bordering Afar, Ethiopia. MSc, Thesis, College of Veterinary Medicine and Agriculture of Addis Ababa University,Bishoftu, Pp. 1–112
AU-IBAR, 2014. Standard methods and procedures (SMPs) for control of peste des petits ruminants (PPR) in the Greater Horn of Africa. Nairobi
Balamurugan V, Sen A, Venkatesan G, Yadav V, hanuprakash V, Singh RK (2010) Isolation and identification of virulent peste des petits ruminants viruses from PPR outbreaks in India. Trop Anim Health Prod 42:1043–1046CrossRefPubMed
Balamurugan V, Hemadri D, Gajendragad MR, Singh RK, Rahman H (2014) Virus Dis 25:39–56CrossRef
Bashir, M.B. 2013. Serological studies on peste des petits ruminants (PPR) in sheep, goats and camels in Sokoto state, Nigeria. MSc, Thesis, Ahmadu Bello University, Zaria
Berihun A, Daniel H, Kassaw H (2014) Seroprevalence of peste des petits ruminants in goats of southern parts of Tigray region. Glob Veterinaria 12(4):512–516
Delil F, Asfaw Y, Gebreegziabher B (2012) Prevalence of antibodies to peste des petits ruminants virus before and during outbreaks of the disease in Awash Fentale district, Afar, Ethiopia. Trop Anim Health Prod 44:1329–1330CrossRefPubMed
Dhar P, Sreenivasa BP, Barrett T, Corteyn M, Singh RP, Bandyopadhyay SK (2002) Recent epidemiology of peste des petits ruminants virus (PPRV). Vet Microbiol 88(2):153–159CrossRefPubMed
Elsawalhy A, Jeffrey C, Dickens C, Henry W, Samuel W, William O, Phillip T (2010) Pan African strategy for the progressive control of PPR. Bull Anim Health Prod Africa:1185–1193
Felix, N. 2013. Current scenario and control initiatives for PPR at global, regional and country level according to the risk factors and socioeconomic impact. In Proceedings of the second regional conference on progressive control of peste des petits ruminants in South Asia, Kathmandu, December 19–20
Geerts, S. 2009. Goat plaque or Peste des petits ruminants. EAZWV Transmissible Disease Fact Sheet No. 25. Antwerp, Institute of Tropical Medicine, Pp. 1–3
Hegde R, Gomes AR, Muniyellappa HK, Byregowda SM, Giridhar P, Renukaprasad C (2009) A short note on peste des petits ruminants in Karnataka. Rev Sci Tech 28(3):1031–1035CrossRefPubMed
Khan HA, Siddique M, Abubakar M, Arshad MJ, Hussain M (2008) Prevalence and distribution of peste des petits ruminants virus infection in small ruminants. Small Rumin Res 79:152–157CrossRef
Kihu, S.S. 2014. Risk factors and socio-economic effects associated with spread of peste des petits ruminants (PPR) in turkana county, Kenya. Phd,thesis, University of Nairobi
Megersa B, Biffa D, Belina T, Debela E, Regassa A, Abunna F, Rufael T, Stubsjøen SM, Skjerve E (2011) Serological investigation of peste des petits ruminants (PPR) in small ruminants managed under pastoral and agro-pastoral systems in Ethiopia. Small Rumin Res 97:134–138CrossRef
Merck, S. and Dohme, C. 2009. The Merck veterinary manual. A subsidiary of Merck & Co., Inc. Whitehouse Station NJ, USA
Pegram RG, Tereke F (1981) Observation on the health of Afar livestock. Ethiop Vet J 5:1–11
Roeder PL, Obi TU (1999) Recognising peste de petits ruminants: a field manual. FAO animal health manual no. 5. Rome, FAO Animal Health, p 28
Roeder PL, Abraham G, Kenfe A, Barrett T (1994) PPR in Ethiopian goats. Trop Anim Healthand Prod 26:69–73CrossRef
Shuaib YA, El-Fadil AAM, Abdel-Rahman ME, Negussie H, Zessin KH (2014) Seroprevalence and risk factors of Peste des petits ruminants in sheep in the Kassala and north Kordofan states of the Sudan. Int J Vet Sci 3(1):18–28
Swai ES, Kapaga A, Kivaria F, Tinuga D, Joshua G, Sanka P (2009) Prevalence and distribution of peste des petits ruminants virus antibodies in various districts of Tanzania. Vet Res Commun 33:927–936CrossRefPubMed
Thrusfield, M. 2007. Veterinary Epidemiology. 3rd Edn. UK, Blackwell Science Ltd, Pp. 233–250
Waret-Szkuta A, Roger F, Chavernac D, Yigezu L, Libeau G, Pfeiffer DU, Guitian J (2008) Peste des petits ruminants (PPR) in Ethiopia: analysis of a national serological survey. Vet Res 4:34
Zahur AB, Ullah A, Irshad H, Farooq MS, Hussain M, Jahangir M (2009) Epidemiological investigations of a peste des petits ruminants (PPR) outbreak in Afghan sheep in Pakistan. Pak Vet J 29:174–178
Zahur AB, Ullah A, Hussain M, Irshad H, Hameed A, Jahangir M, Farooq MS (2011) Sero-epidemiology of peste des petits ruminants (PPR) in Pakistan. Prev Vet Med 102(1):87–92CrossRefPubMed
Zewdie, S. 2009. Peste des petits ruminants (PPR) In: Yami, A.; Merkel, R.C. and Dawson, L. (Eds.) Peste des petits ruminants (PPR), Technical Bulletin No. 20, pp. 1–4, Ethiopia Sheep and Goat Productivity Improvement Programme, USAID and MoARD, Ethiopia
Metadata
Title
Sero-epidemiological study of peste des petits ruminants in small ruminants in Amahara region, Ethiopia
Authors
Tsegaw Fentie
Yechale Teshome
Birhanu Ayele
Wassie Molla
Nigusie Fenta
Seleshe Nigatu
Ashenafe Assefa
Samson Leta
Publication date
01-07-2018
Publisher
Springer London
Published in
Comparative Clinical Pathology / Issue 4/2018
Print ISSN: 1618-5641
Electronic ISSN: 1618-565X
DOI
https://doi.org/10.1007/s00580-018-2697-2

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