Skip to main content
Top
Published in: Langenbeck's Archives of Surgery 1/2011

01-01-2011 | Overview

The formal requirements of algorithms and their implications in clinical medicine and quality management

Authors: Philipe N. Khalil, Axel Kleespies, Martin K. Angele, Wolfgang E. Thasler, Matthias Siebeck, Christiane J. Bruns, Wolf Mutschler, Karl-Georg Kanz

Published in: Langenbeck's Archives of Surgery | Issue 1/2011

Login to get access

Abstract

Purpose

Clinical algorithms contribute to the problem- and priority-orientated management of patients and their disease in healthcare. Algorithms are of particular importance in all aspects of emergency medicine where the fast completion of a complex problem according to a hierarchy is required. The advantages and success of this priority- and problem-orientated concept led to its expansion to other subspecialties in medicine in recent years. However, in spite of algorithms being created based on defined norms, they are frequently violated in the literature, which renders the algorithm useless in a particular case.

Methods

The present debate addresses these issues and provides the formal criteria and their necessary modification for creating sufficient clinical algorithms. In this context, we also clarify the misunderstandings between step-by-step schemes, decision trees, and algorithms, which are often used synonymously, and discuss their implications in clinical medicine and quality management.

Results

A clinical algorithm can easily be created with the present derivation of the algorithm by its formal mathematical function using the corresponding norms describing specific symbols for a single criterion. Some symbol modifications as well as the usage of checklists to focus on the major criteria led to a rigorous reduction of the algorithm length and results in a clearer arrangement for routine clinical use. In clinical medicine, algorithms cannot only provide a fast access for solving complex problems but must also assure a transparent protocol and democratic treatment such that every patient receives the same quality of treatment. Thus, a treatment by chance can be excluded by standardization, which might impact the overall work needed to guide patients though diagnostics and therapy and may ultimately reduce cost. Algorithms are useful not only for quality in healthcare but also for undergraduate and continuous medical education. From a more philosophical point of view, we can raise the question of whether medical pathways and thereby the medical art should be disclosed to the general public by algorithms. Hippocrates form Kos held the view in the so-called Hippocratic Oath that medical art should only be revealed to medical scholars.

Conclusions

The present derivation and nomination of the formal requirements may lead to a better understanding of algorithms themselves as well as their development and generation.
Literature
1.
go back to reference Folkerts M (1997) Die älteste lateinische Schrift über das indische Rechnen nach al-Ḫwārizmī. Verl. der Bayer. Akad. der Wiss., München Folkerts M (1997) Die älteste lateinische Schrift über das indische Rechnen nach al-Ḫwārizmī. Verl. der Bayer. Akad. der Wiss., München
2.
go back to reference Al Daffa AA (1977) The Muslim contribution to mathematics. Croom Helm, London Al Daffa AA (1977) The Muslim contribution to mathematics. Croom Helm, London
3.
go back to reference Gandz S (1936) The sources of al-Khowarizni’s algebra. Osiris 1:263–277CrossRef Gandz S (1936) The sources of al-Khowarizni’s algebra. Osiris 1:263–277CrossRef
4.
go back to reference Kanz KG, Eitel F, Waldner H, Schweiberer L (1994) Development of clinical algorithms for quality assurance in management of multiple trauma. Unfallchirurg 97:303–307PubMed Kanz KG, Eitel F, Waldner H, Schweiberer L (1994) Development of clinical algorithms for quality assurance in management of multiple trauma. Unfallchirurg 97:303–307PubMed
5.
go back to reference Eitel F, Kanz KG, Hortig E, Tesche A (2000) Do we face a fourth paradigm shift in medicine—algorithms in education. J Eval Clin Pract 6:321–333CrossRefPubMed Eitel F, Kanz KG, Hortig E, Tesche A (2000) Do we face a fourth paradigm shift in medicine—algorithms in education. J Eval Clin Pract 6:321–333CrossRefPubMed
6.
go back to reference International Organisation for Standardization (1985) ISO 5807: information processing—document symbols and conventions for data, program and system flowcharts, program network charts and system resource charts. ISO, Geneva International Organisation for Standardization (1985) ISO 5807: information processing—document symbols and conventions for data, program and system flowcharts, program network charts and system resource charts. ISO, Geneva
7.
go back to reference Khalil PN, Huber-Wagner S, Ladurner R, Kleespies A, Siebeck M, Mutschler W, Hallfeldt K, Kanz KG (2009) Natural history, clinical pattern, and surgical considerations of pneumatosis intestinalis. Eur J Med Res 14:231–239PubMed Khalil PN, Huber-Wagner S, Ladurner R, Kleespies A, Siebeck M, Mutschler W, Hallfeldt K, Kanz KG (2009) Natural history, clinical pattern, and surgical considerations of pneumatosis intestinalis. Eur J Med Res 14:231–239PubMed
8.
go back to reference Khalil PN, Huber-Wagner S, Altheim S, Bürklein D, Siebeck M, Hallfeldt K, Mutschler KG, Kanz KG (2008) Diagnosis and treatment options for skin and soft tissue abscesses in injecting drug users with consideration of the natural history and concomitant risk factors. Eur J Med Res 13:415–425PubMed Khalil PN, Huber-Wagner S, Altheim S, Bürklein D, Siebeck M, Hallfeldt K, Mutschler KG, Kanz KG (2008) Diagnosis and treatment options for skin and soft tissue abscesses in injecting drug users with consideration of the natural history and concomitant risk factors. Eur J Med Res 13:415–425PubMed
9.
go back to reference Khalil PN, Hallfeldt K (2008) Diagnosis and therapy of primary hypertparathyroidism. MMW Fortschr Med 150:39–41 Khalil PN, Hallfeldt K (2008) Diagnosis and therapy of primary hypertparathyroidism. MMW Fortschr Med 150:39–41
10.
go back to reference Khalil PN, Ockert B, Huber-Wagner S, Grote S, Kanz KG, Mutschler W (2009) Broken glass injuries: does every splinter have to be removed? MMW Fortschr Med 151:38–40PubMed Khalil PN, Ockert B, Huber-Wagner S, Grote S, Kanz KG, Mutschler W (2009) Broken glass injuries: does every splinter have to be removed? MMW Fortschr Med 151:38–40PubMed
11.
go back to reference Kanz KG, Schmöller G, Enhuber K, Hölzl G, Sturm JA, Mutschler W (2002) Algorithm for extrication and medical care in vehicle trauma. Unfallchirurg 105:1015–1021CrossRefPubMed Kanz KG, Schmöller G, Enhuber K, Hölzl G, Sturm JA, Mutschler W (2002) Algorithm for extrication and medical care in vehicle trauma. Unfallchirurg 105:1015–1021CrossRefPubMed
12.
go back to reference Kanz KG, Sturm JA, Mutschler W (2002) Algorithm for prehospital blunt trauma management. Unfallchirurg 105:1007–1014CrossRefPubMed Kanz KG, Sturm JA, Mutschler W (2002) Algorithm for prehospital blunt trauma management. Unfallchirurg 105:1007–1014CrossRefPubMed
13.
go back to reference Kanz KG, Hornburger P, Kay MV, Mutschler W, Schäuble W (2006) mSTaRTAlgorithmus für Sichtung, Behandlung und Transport bei einem Massenanfall von Verletzten. Notfall Rettungsmed 9:264–277CrossRef Kanz KG, Hornburger P, Kay MV, Mutschler W, Schäuble W (2006) mSTaRTAlgorithmus für Sichtung, Behandlung und Transport bei einem Massenanfall von Verletzten. Notfall Rettungsmed 9:264–277CrossRef
14.
go back to reference Nast-Kolb D, Waydhas C, Kanz KG, Schweiberer L (1994) An algorithm for management of shock in polytrauma. Unfallchirurg 97:292–302PubMed Nast-Kolb D, Waydhas C, Kanz KG, Schweiberer L (1994) An algorithm for management of shock in polytrauma. Unfallchirurg 97:292–302PubMed
15.
go back to reference Dick WF, Ahnefeld FW, Knuth P (1997) Logbuch der Notfallmedizin: algorithmen und checklisten. Springer, Berlin Dick WF, Ahnefeld FW, Knuth P (1997) Logbuch der Notfallmedizin: algorithmen und checklisten. Springer, Berlin
17.
go back to reference Larson KT, Vickery MD, Collis PB (1973) Triage: a logical algorithmic to a non-system. JACEP 2:183–185 Larson KT, Vickery MD, Collis PB (1973) Triage: a logical algorithmic to a non-system. JACEP 2:183–185
18.
go back to reference Shoemaker WC (1975) Algorithm for resuscitation: a systematic plan for immediate care of the injured or postoperative patient. Crit Care Med 3:127–131CrossRefPubMed Shoemaker WC (1975) Algorithm for resuscitation: a systematic plan for immediate care of the injured or postoperative patient. Crit Care Med 3:127–131CrossRefPubMed
19.
go back to reference Bernhard M, Becker TK, Nowe T, Mohorovicic M, Sikinger M, Brenner T, Richter GM, Radeleff B, Meeder PJ, Büchler MW, Böttiger BW, Martin E, Gries A (2007) Introduction of a treatment algorithm can improve the early management of emergency patients in the resuscitation room. Resuscitation 73:362–373CrossRefPubMed Bernhard M, Becker TK, Nowe T, Mohorovicic M, Sikinger M, Brenner T, Richter GM, Radeleff B, Meeder PJ, Büchler MW, Böttiger BW, Martin E, Gries A (2007) Introduction of a treatment algorithm can improve the early management of emergency patients in the resuscitation room. Resuscitation 73:362–373CrossRefPubMed
20.
go back to reference Waydhas C, Kanz KG, Ruchholtz S, Nast-Kolb D (1997) A time and priority-orientated algorithm. Langenbecks Arch Chir Suppl Kongressbd 114:966–969PubMed Waydhas C, Kanz KG, Ruchholtz S, Nast-Kolb D (1997) A time and priority-orientated algorithm. Langenbecks Arch Chir Suppl Kongressbd 114:966–969PubMed
21.
go back to reference Waydhas C, Kanz KG, Ruchholtz S, Nast-Kolb D (1997) Algorithms in trauma management. Unfallchirurg 100:913–921CrossRefPubMed Waydhas C, Kanz KG, Ruchholtz S, Nast-Kolb D (1997) Algorithms in trauma management. Unfallchirurg 100:913–921CrossRefPubMed
22.
go back to reference Shoemaker WC, Corley RD, Liu M, Kram HB, Harrier HD, Williams SW, Flemming AW (1988) Development and testing of a decision tree for blunt trauma. Crit Care Med 16:1199–1208CrossRefPubMed Shoemaker WC, Corley RD, Liu M, Kram HB, Harrier HD, Williams SW, Flemming AW (1988) Development and testing of a decision tree for blunt trauma. Crit Care Med 16:1199–1208CrossRefPubMed
23.
go back to reference Liu M, Shoemaker WC, Kram HB, Harrier HD (1988) Design and prospective evaluation of an algorithm for penetrating truncal injuries. Crit Care Med 16:1191–1198CrossRefPubMed Liu M, Shoemaker WC, Kram HB, Harrier HD (1988) Design and prospective evaluation of an algorithm for penetrating truncal injuries. Crit Care Med 16:1191–1198CrossRefPubMed
24.
go back to reference Ruchholtz S, Zintl B, Nast-Kolb D, Waydhas C, Lewan U, Kanz KG, Schwender D, Pfeifer KJ, Schweiberer L (1989) Improvement in the therapy of multiple injured patients by introduction of clinical management guidelines. Injury 29:115–129CrossRef Ruchholtz S, Zintl B, Nast-Kolb D, Waydhas C, Lewan U, Kanz KG, Schwender D, Pfeifer KJ, Schweiberer L (1989) Improvement in the therapy of multiple injured patients by introduction of clinical management guidelines. Injury 29:115–129CrossRef
25.
go back to reference American College of Surgeons (2008) Advanced trauma life support—program for doctors: 8th edn. American College of Surgeons, Chicago American College of Surgeons (2008) Advanced trauma life support—program for doctors: 8th edn. American College of Surgeons, Chicago
26.
go back to reference Jotterand F (2005) The Hippocratic Oath and contemporary medicine: dialectic between past ideals and present reality? J Med Philos 30:107–128CrossRefPubMed Jotterand F (2005) The Hippocratic Oath and contemporary medicine: dialectic between past ideals and present reality? J Med Philos 30:107–128CrossRefPubMed
27.
go back to reference Markel H (2004) “I swear by Apollo”—on talking the Hippocratic Oath. New Engl J Med 350:2026–2029CrossRefPubMed Markel H (2004) “I swear by Apollo”—on talking the Hippocratic Oath. New Engl J Med 350:2026–2029CrossRefPubMed
Metadata
Title
The formal requirements of algorithms and their implications in clinical medicine and quality management
Authors
Philipe N. Khalil
Axel Kleespies
Martin K. Angele
Wolfgang E. Thasler
Matthias Siebeck
Christiane J. Bruns
Wolf Mutschler
Karl-Georg Kanz
Publication date
01-01-2011
Publisher
Springer-Verlag
Published in
Langenbeck's Archives of Surgery / Issue 1/2011
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-010-0713-3

Other articles of this Issue 1/2011

Langenbeck's Archives of Surgery 1/2011 Go to the issue