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Current Nutrition Reports
Published in: Current Nutrition Reports 4/2014

Open Access 01-12-2014 | Public Health and Translational Medicine (PW Franks, Section Editor)

The EPIC-InterAct Study: A Study of the Interplay between Genetic and Lifestyle Behavioral Factors on the Risk of Type 2 Diabetes in European Populations

Authors: Nita G. Forouhi, Nicholas J. Wareham

Published in: Current Nutrition Reports | Issue 4/2014

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Abstract

The rising prevalence of type 2 diabetes around the world and the global pattern of variation in risk between countries have been widely attributed to an interplay between rising rates of obesity and poor lifestyles, and genetic or developmental susceptibility to disease. Although this general hypothesis has been in existence for more than 50 years, the precise mechanisms that may explain it have remained uncertain. Advances in technology and the application of new methods in large scale population studies have made it possible to study these mechanisms. The InterAct project, funded by the European Commission, is a large case-cohort study which has verified 12,403 incident cases of type 2 diabetes, facilitating the study of genetic and lifestyle factors on the risk of type 2 diabetes among European populations.
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Metadata
Title
The EPIC-InterAct Study: A Study of the Interplay between Genetic and Lifestyle Behavioral Factors on the Risk of Type 2 Diabetes in European Populations
Authors
Nita G. Forouhi
Nicholas J. Wareham
Publication date
01-12-2014
Publisher
Springer US
Published in
Current Nutrition Reports / Issue 4/2014
Electronic ISSN: 2161-3311
DOI
https://doi.org/10.1007/s13668-014-0098-y

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