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01-04-2019 | Original Article

The cardiovascular risk factors in men with lower urinary tract symptoms

Authors: Chi-hang Yee, Jenny S. Y. Yip, Nicole M. Y. Cheng, Cheuk-hang Kwan, Kai-man Li, Jeremy Y. C. Teoh, Peter K. F. Chiu, Joseph Hon-ming Wong, Eddie S. Y. Chan, Chi-kwok Chan, Simon S. M. Hou, Chi-fai Ng

Published in: World Journal of Urology | Issue 4/2019

Abstract

Objective

It has been hypothesized that endothelial dysfunction and pelvic atherosclerosis may contribute to lower urinary tract symptoms (LUTS). We assessed the relationship between cardiovascular risk factors and LUTS severity in male patients presented to urology clinic.

Methods

It is a cross-sectional study on patients who presented between 2013 and 2015 with LUTS. A total of 1176 male patients were encountered, and 966 were included for analysis after excluding patients with urinary tract malignancy, urethral stricture, bladder stone and history of urinary tract surgery. Cardiovascular risk factors including components of Framingham risk score, body mass index, uroflowmetry, International Prostate Symptoms Score, fasting blood glucose and serum prostate-specific antigen (PSA) were assessed. Correlation between Framingham risk score, cardiovascular risk factors and severity of LUTS was investigated.

Results

Multinomial logistic regression analysis showed that severe LUTS significantly associated with Framingham score (P = 0.008) and its components of total cholesterol (OR = 1.318; P = 0.010) and age (OR = 1.032; P = 0.006) compare with mild symptoms. Framingham risk score was found to correlate with storage symptoms (CC = 0.083; P < 0.0001) but not voiding symptoms (CC = − 0.029; P = 0.185).

Conclusions

Severity of LUTS and storage symptom significantly increases Framingham risk score, particularly with the components of total cholesterol level and age.

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Title: The cardiovascular risk factors in men with lower urinary tract symptoms
Authors: Chi-hang Yee
Jenny S. Y. Yip
Nicole M. Y. Cheng
Cheuk-hang Kwan
Kai-man Li
Jeremy Y. C. Teoh
Peter K. F. Chiu
Joseph Hon-ming Wong
Eddie S. Y. Chan
Chi-kwok Chan
Simon S. M. Hou
Chi-fai Ng
Publication date: 01-04-2019
Publisher: Springer Berlin Heidelberg
Published in: World Journal of Urology / Issue 4/2019
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-018-2432-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The cardiovascular risk factors in men with lower urinary tract symptoms

Abstract

Objective

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Methods

Results

Conclusions

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