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European Journal of Medical Research
Published in: European Journal of Medical Research 12/2011

01-12-2011 | Case report

Tenofovir induced acute kidney injury in a patient with unilateral renal agenesis despite initially non-impaired renal function

Authors: BT Schleenvoigt, A Stallmach, MW Pletz

Published in: European Journal of Medical Research | Issue 12/2011

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Abstract

Nephrotoxicity is observed in 1.6 % of patients treated with tenofovir disoproxil fumarat Fux 2007.
Literature
1.
Bellomo R, Ronco C, Kellum JA, et al.: Acute renal failure definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 2004,8(4):R204–12. Epub 2004 May 24 10.1186/cc2872PubMedCentralPubMedCrossRef
2.
Fux CA, Simcock M, Wolbers M, et al.: Tenofovir use is associated with a reduction in calculated glomerular filtration rates in the Swiss HIV Cohort Study. Antivir Ther 2007,12(8):1165–73.PubMed
3.
Lennox JL, DeJesus E, Lazzarin A, et al.: Safety and efficacy of raltegravir-based versus efavirenz-based combination therapy in treatment-naive patients with HIV-1 infection: a multicentre, double-blind randomised controlled trial. Lancet 2009,374(9692):796–806. Epub 2009 Aug 3 10.1016/S0140-6736(09)60918-1PubMedCrossRef
4.
Herlitz LC, Mohan S, Stokes MB, Radhakrishnan J, D'Agati VD, Markowitz GS: Tenofovir nephrotoxicity: acute tubular necrosis with distinctive clinical, pathological, and mitochondrial abnormalities. Kidney Int 2010,78(11):1171–7. Epub 2010 Sep 1 10.1038/ki.2010.318PubMedCrossRef
Metadata
Title
Tenofovir induced acute kidney injury in a patient with unilateral renal agenesis despite initially non-impaired renal function
Authors
BT Schleenvoigt
A Stallmach
MW Pletz
Publication date
01-12-2011
Publisher
BioMed Central
Published in
European Journal of Medical Research / Issue 12/2011
Electronic ISSN: 2047-783X
DOI
https://doi.org/10.1186/2047-783X-16-12-564

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