Skip to main content
Top
Published in: Pediatric Cardiology 7/2013

01-10-2013 | Original Article

Temporary Atrial Pacing for Cardiac Output After Pediatric Cardiac Surgery

Authors: Gregory M. Barker, Jeremy Affolter, Jessica Saenz, Casey S. Cox, Joseph M. Forbess, William A. Scott, Ilana Zeltser

Published in: Pediatric Cardiology | Issue 7/2013

Login to get access

Abstract

Pediatric cardiothoracic surgery is often associated with low cardiac output in the postoperative period. This study sought to determine whether increasing heart rate via temporary atrial pacing is beneficial in augmenting cardiac output. Patients younger than 18 years who underwent cardiothoracic surgery and had no perioperative arrhythmias were eligible for the study. Patients not paced postoperatively were atrial paced at a rate of 15 % above the intrinsic sinus rate (not to exceed 170 beats per minute, less for older patients) for 15 min. Patients paced for cardiac output postoperatively had their pacemakers paused for 15 min. Markers of cardiac output were measured before and after the intervention. Of the 60 patients who consented to participate, 30 completed the study. Failure to complete the study was due to tachycardia (n = 13), lack of pacing wires (n = 7), junctional rhythm (n = 4), advanced atrioventricular block (n = 3), and other cause (n = 3). Three patients were paced at baseline. There was no change in arteriovenous oxygen saturation difference, mean arterial blood pressure, central venous pressure, toe temperature, or lactate with atrial pacing. Atrial pacing was associated with a decrease in head and flank near-infrared spectroscopy (p = 0.01 and <0.01 respectively). Secondary analysis found an inverse relationship between mean arterial pressure response to pacing and bypass time. Temporary atrial pacing does not improve cardiac output after pediatric cardiac surgery and may be deleterious. Future research may identify subsets of patients who benefit from this strategy. Practitioners considering this strategy should carefully evaluate each patient’s response to atrial pacing before its implementation.
Literature
1.
go back to reference Barber BJ, Batra AS, Burch GH, Shen I, Ungerleider RM, Brown JW, Turrentine MW, Mori M, Hsieh YC, Balaji S (2005) Acute hemodynamic effects of pacing in patients with Fontan physiology: a prospective study. J Am Coll Cardiol 46:1937–1942CrossRefPubMed Barber BJ, Batra AS, Burch GH, Shen I, Ungerleider RM, Brown JW, Turrentine MW, Mori M, Hsieh YC, Balaji S (2005) Acute hemodynamic effects of pacing in patients with Fontan physiology: a prospective study. J Am Coll Cardiol 46:1937–1942CrossRefPubMed
2.
go back to reference Benchimol A, Liggett MS (1966) Cardiac hemodynamics during stimulation of the right atrium, right ventricle, and left ventricle in normal and abnormal hearts. Circulation 33:933–944CrossRefPubMed Benchimol A, Liggett MS (1966) Cardiac hemodynamics during stimulation of the right atrium, right ventricle, and left ventricle in normal and abnormal hearts. Circulation 33:933–944CrossRefPubMed
3.
go back to reference Ceresnak SR, Pass RH, Starc TJ, Hordof AJ, Bonney WJ, Mosca RS, Liberman L (2011) Predictors for hemodynamic improvement with temporary pacing after pediatric cardiac surgery. J Thorac Cardiovasc Surg 141:183–187CrossRefPubMed Ceresnak SR, Pass RH, Starc TJ, Hordof AJ, Bonney WJ, Mosca RS, Liberman L (2011) Predictors for hemodynamic improvement with temporary pacing after pediatric cardiac surgery. J Thorac Cardiovasc Surg 141:183–187CrossRefPubMed
4.
go back to reference Fleck T, Schubert S, Redlin M, Stiller B, Ewert P, Berger F, Nagdyman N (2010) Influence of external cardiac pacing on cerebral oxygenation measured by near-infrared spectroscopy in children after cardiac surgery. Paediatr Anaesth 20:553–558CrossRefPubMed Fleck T, Schubert S, Redlin M, Stiller B, Ewert P, Berger F, Nagdyman N (2010) Influence of external cardiac pacing on cerebral oxygenation measured by near-infrared spectroscopy in children after cardiac surgery. Paediatr Anaesth 20:553–558CrossRefPubMed
5.
go back to reference Gulielmos V, Kappert U, Eller M, Sahre H, Alexiou K, Georgi C, Nicolai J, Hartmann N (2003) Improving hemodynamics by atrial pacing during off-pump bypass surgery. Heart Surg Forum 6:E179–E182PubMed Gulielmos V, Kappert U, Eller M, Sahre H, Alexiou K, Georgi C, Nicolai J, Hartmann N (2003) Improving hemodynamics by atrial pacing during off-pump bypass surgery. Heart Surg Forum 6:E179–E182PubMed
6.
go back to reference Hoffman TM, Wernovsky G, Atz AM, Kulik TJ, Nelson DP, Chang AC, Bailey JM, Akbary A, Kocsis JF, Kaczmarekiz R, Spray TL, Wessel DL (2003) Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease. Circulation 107:996–1002CrossRefPubMed Hoffman TM, Wernovsky G, Atz AM, Kulik TJ, Nelson DP, Chang AC, Bailey JM, Akbary A, Kocsis JF, Kaczmarekiz R, Spray TL, Wessel DL (2003) Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease. Circulation 107:996–1002CrossRefPubMed
7.
go back to reference Hung J, Kelly DT, Hutton BF, Uther JB, Baird DK (1981) Influence of heart rate and atrial transport on left ventricular volume and function: relation to hemodynamic changes produced by supraventricular arrhythmia. Am J Cardiol 48:632–638CrossRefPubMed Hung J, Kelly DT, Hutton BF, Uther JB, Baird DK (1981) Influence of heart rate and atrial transport on left ventricular volume and function: relation to hemodynamic changes produced by supraventricular arrhythmia. Am J Cardiol 48:632–638CrossRefPubMed
8.
go back to reference Kaufman J, Almodovar MC, Zuk J, Friesen RH (2008) Correlation of abdominal site near-infrared spectroscopy with gastric tonometry in infants following surgery for congenital heart disease. Pediatr Crit Care Med 9:62–68CrossRefPubMed Kaufman J, Almodovar MC, Zuk J, Friesen RH (2008) Correlation of abdominal site near-infrared spectroscopy with gastric tonometry in infants following surgery for congenital heart disease. Pediatr Crit Care Med 9:62–68CrossRefPubMed
9.
go back to reference Kirshbom PM, Forbess JM, Kogon BE, Simsic JM, Kim DW, Raviele AA, Kanter KR, Vincent RN (2007) Cerebral near-infrared spectroscopy is a reliable marker of systemic perfusion in awake single ventricle children. Pediatr Cardiol 28:42–45CrossRefPubMed Kirshbom PM, Forbess JM, Kogon BE, Simsic JM, Kim DW, Raviele AA, Kanter KR, Vincent RN (2007) Cerebral near-infrared spectroscopy is a reliable marker of systemic perfusion in awake single ventricle children. Pediatr Cardiol 28:42–45CrossRefPubMed
10.
go back to reference Klopfenstein HS, Rudolph AM (1978) Postnatal changes in the circulation and responses to volume loading in sheep. Circ Res 42:839–845CrossRefPubMed Klopfenstein HS, Rudolph AM (1978) Postnatal changes in the circulation and responses to volume loading in sheep. Circ Res 42:839–845CrossRefPubMed
11.
go back to reference Kwapisz MM, Neuhauser C, Scholz S, Welters ID, Lohr T, Koch T, Valeske K, Akinturk H, Thul J, Muller M (2009) Hemodynamic effects of dobutamine and dopexamine after cardiopulmonary bypass in pediatric cardiac surgery. Paediatr Anaesth 19:862–871CrossRefPubMed Kwapisz MM, Neuhauser C, Scholz S, Welters ID, Lohr T, Koch T, Valeske K, Akinturk H, Thul J, Muller M (2009) Hemodynamic effects of dobutamine and dopexamine after cardiopulmonary bypass in pediatric cardiac surgery. Paediatr Anaesth 19:862–871CrossRefPubMed
12.
go back to reference Nagdyman N, Fleck T, Schubert S, Ewert P, Peters B, Lange PE, Abdel-Khaliq H (2005) Comparison between cerebral tissue oxygenation index measured by near-infrared spectroscopy and venous jugular bulb saturation in children. Intensive Care Med 31:846–850CrossRefPubMed Nagdyman N, Fleck T, Schubert S, Ewert P, Peters B, Lange PE, Abdel-Khaliq H (2005) Comparison between cerebral tissue oxygenation index measured by near-infrared spectroscopy and venous jugular bulb saturation in children. Intensive Care Med 31:846–850CrossRefPubMed
13.
go back to reference Ortmann LA, Fontenot EE, Seib PM, Eble BK, Brown R, Bhutta AT (2011) Use of near-infrared spectroscopy for estimation of renal oxygenation in children with heart disease. Pediatr Cardiol 32:748–753CrossRefPubMed Ortmann LA, Fontenot EE, Seib PM, Eble BK, Brown R, Bhutta AT (2011) Use of near-infrared spectroscopy for estimation of renal oxygenation in children with heart disease. Pediatr Cardiol 32:748–753CrossRefPubMed
14.
go back to reference Pfammatter JP, Wagner B, Berdat P, Bachmann DC, Pavlovic M, Pfenninger J, Carrel T (2002) Procedural factors associated with early postoperative arrhythmias after repair of congenital heart defects. J Thorac Cardiovasc Surg 123:258–262CrossRefPubMed Pfammatter JP, Wagner B, Berdat P, Bachmann DC, Pavlovic M, Pfenninger J, Carrel T (2002) Procedural factors associated with early postoperative arrhythmias after repair of congenital heart defects. J Thorac Cardiovasc Surg 123:258–262CrossRefPubMed
15.
go back to reference Ross J Jr, Linhart JW, Brauwald E (1965) Effects of changing heart rate in man by electrical stimulation of the right atrium: studies at rest, during exercise, and with isoproterenol. Circulation 32:549–558CrossRefPubMed Ross J Jr, Linhart JW, Brauwald E (1965) Effects of changing heart rate in man by electrical stimulation of the right atrium: studies at rest, during exercise, and with isoproterenol. Circulation 32:549–558CrossRefPubMed
16.
go back to reference Teitel DF, Sidi D, Chin T, Brett C, Heymann MA, Rudolph AM (1985) Developmental changes in myocardial contractile reserve in the lamb. Pediatr Res 19:948–955CrossRefPubMed Teitel DF, Sidi D, Chin T, Brett C, Heymann MA, Rudolph AM (1985) Developmental changes in myocardial contractile reserve in the lamb. Pediatr Res 19:948–955CrossRefPubMed
17.
go back to reference Tortoriello TA, Stayer SA, Mott AR, McKenzie ED, Fraser CD, Andropoulos DB, Chang AC (2005) A noninvasive estimation of mixed venous oxygen saturation using near-infrared spectroscopy by cerebral oximetry in pediatric cardiac surgery patients. Paediatr Anaesth 15:495–503CrossRefPubMed Tortoriello TA, Stayer SA, Mott AR, McKenzie ED, Fraser CD, Andropoulos DB, Chang AC (2005) A noninvasive estimation of mixed venous oxygen saturation using near-infrared spectroscopy by cerebral oximetry in pediatric cardiac surgery patients. Paediatr Anaesth 15:495–503CrossRefPubMed
18.
go back to reference Valsangiacomo E, Schmid ER, Schupbach RW, Schmidlin D, Molinari L, Waldvogel K, Bauersfeld U (2002) Early postoperative arrhythmias after cardiac operation in children. Ann Thorac Surg 74:792–796CrossRefPubMed Valsangiacomo E, Schmid ER, Schupbach RW, Schmidlin D, Molinari L, Waldvogel K, Bauersfeld U (2002) Early postoperative arrhythmias after cardiac operation in children. Ann Thorac Surg 74:792–796CrossRefPubMed
19.
go back to reference Wernovsky G, Wypij D, Jonas RA, Mayer JE Jr, Hanley FL, Hickey PR, Walsh AL, Chang AC, Casteneda AR, Newberger JW, Wessel DL (1995) Postoperative course and hemodynamic profile after the arterial switch operation in neonates and infants: a comparison of low-flow cardiopulmonary bypass and circulatory arrest. Circulation 92:2226–2235CrossRefPubMed Wernovsky G, Wypij D, Jonas RA, Mayer JE Jr, Hanley FL, Hickey PR, Walsh AL, Chang AC, Casteneda AR, Newberger JW, Wessel DL (1995) Postoperative course and hemodynamic profile after the arterial switch operation in neonates and infants: a comparison of low-flow cardiopulmonary bypass and circulatory arrest. Circulation 92:2226–2235CrossRefPubMed
20.
go back to reference Wessel DL (2001) Managing low cardiac output syndrome after congenital heart surgery. Crit Care Med 29:S220–S230CrossRefPubMed Wessel DL (2001) Managing low cardiac output syndrome after congenital heart surgery. Crit Care Med 29:S220–S230CrossRefPubMed
Metadata
Title
Temporary Atrial Pacing for Cardiac Output After Pediatric Cardiac Surgery
Authors
Gregory M. Barker
Jeremy Affolter
Jessica Saenz
Casey S. Cox
Joseph M. Forbess
William A. Scott
Ilana Zeltser
Publication date
01-10-2013
Publisher
Springer US
Published in
Pediatric Cardiology / Issue 7/2013
Print ISSN: 0172-0643
Electronic ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-013-0687-3

Other articles of this Issue 7/2013

Pediatric Cardiology 7/2013 Go to the issue