Published in:
01-02-2014 | Editorial
Systemic therapy of renal cell carcinoma
Authors:
Viktor Grünwald, Alain Ravaud
Published in:
World Journal of Urology
|
Issue 1/2014
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Excerpt
The first licensed targeted agents had access to the markets in Europe in 2006, which catalyzed a rapid development of such drugs in metastatic renal cell carcinoma (mRCC). In recent years, different tyrosine kinase inhibitors (TKI) were tested, exploiting the inhibition of neoangiogenesis in mRCC. Numerous studies later, the TKI hype is over and has ceased expectations regarding treatment outcome in mRCC. …