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BMC Musculoskeletal Disorders
Published in: BMC Musculoskeletal Disorders 1/2024

Open Access 01-12-2024 | Systemic Lupus Erythematosus | Research

Musculoskeletal symptoms in systemic lupus erythematosus patients and their impact on health-related quality of life

Authors: Samar Tharwat, Sara Mahmood Husain

Published in: BMC Musculoskeletal Disorders | Issue 1/2024

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Abstract

Objectives

To evaluate the musculoskeletal (MSK) symptoms experienced by SLE patients and determine how those symptoms relate to their health-related quality of life (HRQoL).

Materials and methods

This is a cross-sectional study that was carried out on 103 adult SLE patients. sociodemographic, clinical, and therapeutic data were recruited. They were asked to complete the following: Nordic Musculoskeletal, Short-Form McGill Pain, and Lupus QoL Questionnaires.

Results

The mean age was 30.81 ± 9.44 years. There was a total of 86 females and 17 males (F: M:5:1). Almost all the patients reported MSK symptoms (96.1%). The maximum number of patients reported pain in the right and left wrist and hand (64.1%, 63.1%, respectively). One-fourth (25.2%) described at least five bodily sites of MSK symptoms, while 70.9% had more than five sites of MSK symptoms. Most of the patients described the pain as discomforting (40.8%). Patients with MSK symptoms scored significantly worse in all domains. In addition, the QoL scores of patients with more than 5 body sites of MSK symptoms were significantly lower than those of patients with fewer than 5 sites of MSK symptoms.

Conclusion

SLE patients have a high MSK burden, and MSK symptoms have a negative impact on HRQoL in these patients.
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Metadata
Title
Musculoskeletal symptoms in systemic lupus erythematosus patients and their impact on health-related quality of life
Authors
Samar Tharwat
Sara Mahmood Husain
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2024
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/s12891-024-07367-4

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