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Diabetologia
Published in: Diabetologia 2/2015

01-02-2015 | Letter

Surrogate measures of insulin sensitivity vs the hyperinsulinaemic–euglycaemic clamp: a meta-analysis. Are there not some surrogate indexes lost in this story? Reply to Bastard JP, Rabasa-Lhoret R, Laville M and Disse E [letter]

Authors: Julia Otten, Bo Ahrén, Tommy Olsson

Published in: Diabetologia | Issue 2/2015

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Excerpt

To the Editor: We agree with Dr Bastard and colleagues [1] that the variety of available tools provides an opportunity to assess different aspects of insulin sensitivity. In our extensive literature search on surrogate measures of insulin sensitivity, we found estimations of the correlation to the hyperinsulinaemic–euglycaemic clamp (HEC) for 31 indices based on fasting samples and 65 indices based on the OGTT [2]. …
Literature
1.
Bastard JP, Rabasa-Lhoret R, Laville M, Disse E (2014) Surrogate measures of insulin sensitivity vs the hyperinsulinaemic-euglycaemic clamp: a meta-analysis. Are there not some surrogate indexes lost in this story? Diabetologia doi 10.​1007/​s00125-014-3424-4
2.
Otten J, Ahrén B, Olsson T (2014) Surrogate measures of insulin sensitivity vs the hyperinsulinaemic–euglycaemic clamp: a meta-analysis. Diabetologia 57:1781–1788PubMedCrossRef
3.
Lorenzo C, Haffner SM, Stancakova A, Laakso M (2010) Relation of direct and surrogate measures of insulin resistance to cardiovascular risk factors in nondiabetic Finnish offspring of type 2 diabetic individuals. J Clin Endocrinol Metab 95:5082–5090PubMedCrossRef
4.
Pigeon E, Riou ME, St-Onge J et al (2009) Validation of a simple index (SIisOGTT) of insulin sensitivity in a population of sedentary men. Diabetes Metab 35:398–403PubMedCrossRef
5.
Bastard JP, Lavoie ME, Messier V, Prud’homme D, Rabasa-Lhoret R (2012) Evaluation of two new surrogate indices including parameters not using insulin to assess insulin sensitivity/resistance in non-diabetic postmenopausal women: a MONET group study. Diabetes Metab 38:258–263PubMedCrossRef
Metadata
Title
Surrogate measures of insulin sensitivity vs the hyperinsulinaemic–euglycaemic clamp: a meta-analysis. Are there not some surrogate indexes lost in this story? Reply to Bastard JP, Rabasa-Lhoret R, Laville M and Disse E [letter]
Authors
Julia Otten
Bo Ahrén
Tommy Olsson
Publication date
01-02-2015
Publisher
Springer Berlin Heidelberg
Published in
Diabetologia / Issue 2/2015
Print ISSN: 0012-186X
Electronic ISSN: 1432-0428
DOI
https://doi.org/10.1007/s00125-014-3449-8

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Keynote webinar | Spotlight on medication adherence

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