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European Surgery
Published in: European Surgery 5/2016

01-10-2016 | review article

Surgical use of fibrin glue-coated collagen patch for non-hemostatic indications

A review

Authors: Dimitrios Sampanis, MD, PhD, Maria Siori, MD, PhD

Published in: European Surgery | Issue 5/2016

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Summary

TachoSil and its predecessor products, TachoComb and TachoComb H, have been extensively used in a variety of multidisciplinary surgical settings since being introduced in the early 1990s. However, to date, TachoSil remains the first and only dual action patch for general tissue sealing and is frequently used in variety of surgical indications other than haemostasis. Classically, TachoSil is indicated for improvement of haemostasis. However, there is recently some evidence suggesting that it can be successfully used in promoting tissue healing, which could be useful in various non-hemostatic indications. TachoSil is safe and well tolerated, with occurrence of adverse events similar in TachoSil and non-TachoSil treated patients in controlled trials. The clinical implications of such an approach are obvious. Despite its cost, potential benefits could easily translate into cost savings due to avoidance of complications and to reduction of duration of hospital stay. Existing data are limited and further randomized controlled studies are needed to accurately establish the role of TachoSil for non-hemostatic indications in a variety of surgical indications, such as in abdominal and gastrointestinal surgery, pulmonary surgery, cardiothoracic surgery, renal surgery, gynecology, neurosurgery and more.
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Metadata
Title
Surgical use of fibrin glue-coated collagen patch for non-hemostatic indications
A review
Authors
Dimitrios Sampanis, MD, PhD
Maria Siori, MD, PhD
Publication date
01-10-2016
Publisher
Springer Vienna
Published in
European Surgery / Issue 5/2016
Print ISSN: 1682-8631
Electronic ISSN: 1682-4016
DOI
https://doi.org/10.1007/s10353-016-0436-y

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