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Published in: Child's Nervous System 7/2017

01-07-2017 | Focus Session

Surgical techniques for open fetal repair of myelomeningocele

Author: Nalin Gupta

Published in: Child's Nervous System | Issue 7/2017

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Abstract

The current standard for fetal repair of myelomeningocele is an open exposure of the gravid uterus with control of the amniotic membranes, and then a multi-layer closure of the fetal defect. The nature of the surgical repair has evolved and requires a series of steps that take into account the delicate nature of the fetal tissues. The individual surgical steps are described including potential pitfalls.
Literature
2.
go back to reference Copp AJ, Greene ND, Murdoch JN (2003) The genetic basis of mammalian neurulation. Nat Rev Genet 4:784–793CrossRefPubMed Copp AJ, Greene ND, Murdoch JN (2003) The genetic basis of mammalian neurulation. Nat Rev Genet 4:784–793CrossRefPubMed
3.
go back to reference Rintoul NE, Sutton LN, Hubbard AM, Cohen B, Melchionni J, Pasquariello PS, Adzick NS (2002) A new look at myelomeningoceles: functional level, vertebral level, shunting, and the implications for fetal intervention. Pediatrics 109:409–413CrossRefPubMed Rintoul NE, Sutton LN, Hubbard AM, Cohen B, Melchionni J, Pasquariello PS, Adzick NS (2002) A new look at myelomeningoceles: functional level, vertebral level, shunting, and the implications for fetal intervention. Pediatrics 109:409–413CrossRefPubMed
4.
go back to reference Hutchins GM, Meuli M, Meuli-Simmen C, Jordan MA, Heffez DS, Blakemore KJ (1996) Acquired spinal cord injury in human fetuses with myelomeningocele. Pediatr Pathol Lab Med 16:701–712CrossRefPubMed Hutchins GM, Meuli M, Meuli-Simmen C, Jordan MA, Heffez DS, Blakemore KJ (1996) Acquired spinal cord injury in human fetuses with myelomeningocele. Pediatr Pathol Lab Med 16:701–712CrossRefPubMed
5.
go back to reference Adzick NS, Thom EA, Spong CY, Brock JW 3rd, Burrows PK, Johnson MP, Howell LJ, Farrell JA, Dabrowiak ME, Sutton LN, Gupta N, Tulipan NB, D’Alton ME, Farmer DL (2011) A randomized trial of prenatal versus postnatal repair of myelomeningocele. N Engl J Med 364:993–1004CrossRefPubMedPubMedCentral Adzick NS, Thom EA, Spong CY, Brock JW 3rd, Burrows PK, Johnson MP, Howell LJ, Farrell JA, Dabrowiak ME, Sutton LN, Gupta N, Tulipan NB, D’Alton ME, Farmer DL (2011) A randomized trial of prenatal versus postnatal repair of myelomeningocele. N Engl J Med 364:993–1004CrossRefPubMedPubMedCentral
6.
go back to reference Patel TR, Bannister CM, Thorne J (2003) A study of prenatal ultrasound and postnatal magnetic imaging in the diagnosis of central nervous system abnormalities. Eur J Pediatr Surg 13(Suppl 1):S18–S22PubMed Patel TR, Bannister CM, Thorne J (2003) A study of prenatal ultrasound and postnatal magnetic imaging in the diagnosis of central nervous system abnormalities. Eur J Pediatr Surg 13(Suppl 1):S18–S22PubMed
Metadata
Title
Surgical techniques for open fetal repair of myelomeningocele
Author
Nalin Gupta
Publication date
01-07-2017
Publisher
Springer Berlin Heidelberg
Published in
Child's Nervous System / Issue 7/2017
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-017-3439-5

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