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International Journal of Colorectal Disease

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01-06-2020 | Surgery | Original Article

Indocyanine green fluorescence angiography to evaluate anastomotic perfusion in colorectal surgery

Authors: Yi-po Tsang, Lik-Hang Alex Leung, Chi-wai Lau, Chung-ngai Tang

Published in: International Journal of Colorectal Disease | Issue 6/2020

Abstract

Background

The aim of this study was to evaluate the efficacy of indocyanine green (ICG) fluorescence angiography with respect to the anastomotic leakage rate for patients undergoing colorectal operations.

Methods

This prospective cohort involved patients who underwent colorectal surgery between August 2018 and September 2019. ICG was injected after colonic transection. Vascular perfusion was observed by ICG fluorescence system before completing anastomosis. Data was compared with those by subjective visual evaluation. The primary outcome was anastomotic leakage rate within 30 days from surgery.

Results

A total of 131 patients were enrolled, of which ICG was injected in 63 of them. Demographic data were similar between the two groups. There were two (3.23%) and three (4.35%) anastomotic leaks in the ICG and non-ICG group respectively (p = 1.000). Change of resection plane occurred in one patient in the ICG group. There was no ICG related toxicity or adverse events.

Conclusion

ICG fluorescent imaging is a feasible and safe tool to assess colonic vascularisation for patients undergoing colorectal surgery. However, it did not significantly lower the anastomotic leakage rate. ICG should not be routinely used in colorectal surgery before an available large scale randomised controlled trial to prove any clinical benefits.

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Title: Indocyanine green fluorescence angiography to evaluate anastomotic perfusion in colorectal surgery
Authors: Yi-po Tsang
Lik-Hang Alex Leung
Chi-wai Lau
Chung-ngai Tang
Publication date: 01-06-2020
Publisher: Springer Berlin Heidelberg
Keywords: Surgery
Angiography
Published in: International Journal of Colorectal Disease / Issue 6/2020
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI: https://doi.org/10.1007/s00384-020-03592-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Indocyanine green fluorescence angiography to evaluate anastomotic perfusion in colorectal surgery

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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