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Published in: Sleep and Breathing 2/2013

01-05-2013 | Review

Supine fluid redistribution: should we consider this as an important risk factor for obstructive sleep apnea?

Author: Aibek E. Mirrakhimov

Published in: Sleep and Breathing | Issue 2/2013

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Abstract

Introduction

Obstructive sleep apnea (OSA) is a common medical disorder affecting at least 2 % of women and 4 % of men living in Western societies. Obesity, older age, male gender, alcohol and sedative use, smoking, craniofacial parameters, and volume overload are some of the risk factors for this disorder.

Discussion

OSA is a known risk factor complicating the course of arterial hypertension, heart failure, and chronic kidney disease. It is important to note that all of the aforementioned comorbid disorders are associated with volume overload. This explains why patients with OSA and comorbid disorders associated with fluid overload can benefit from treatment with diuretics and drugs modulating the renin–angiotensin–aldosterone system. Additionally, patients with heart failure and high sodium intake are at increased risk for OSA, further supporting the complex interrelationship.

Conclusions

Hemodialysis and renal transplantation can markedly improve the severity of OSA in patients with concomitant kidney disease. Finally, there is a potential of a vicious cycle between OSA and fluid overload disorders, whereby OSA can contribute to the pathogenesis of arterial hypertension, heart failure, and chronic kidney disease, which in turn will significantly contribute to the course OSA.
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Metadata
Title
Supine fluid redistribution: should we consider this as an important risk factor for obstructive sleep apnea?
Author
Aibek E. Mirrakhimov
Publication date
01-05-2013
Publisher
Springer-Verlag
Published in
Sleep and Breathing / Issue 2/2013
Print ISSN: 1520-9512
Electronic ISSN: 1522-1709
DOI
https://doi.org/10.1007/s11325-012-0755-6

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