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Open Access 01-12-2014 | Case report

Superior mediastinal paraganglioma associated with von Hippel-Lindau syndrome: report of a case

Authors: Tsuyoshi Takahashi, Hiroshi Nogimura, Ken Kuriki, Ryo Kobayashi

Published in: World Journal of Surgical Oncology | Issue 1/2014

Abstract

Extra-adrenal pheochromocytomas are termed paragangliomas. Paragangliomas in the mediastinum, especially the superior mediastinum, are extremely rare. It is known that paragangliomas or pheochromocytomas occur in combination with von Hippel-Lindau syndrome. We present the case of a non-functional superior mediastinal paraganglioma in a patient with von Hippel-Lindau syndrome, without a familial history suggestive of the condition. This case highlights that we should be aware of possible sporadic von Hippel-Lindau syndrome in patients with a mediastinal paraganglioma.

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Neuman HPH: Pheochromocytoma. Harrison’s Principles of Internal Medicine. Edited by: Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL, Loscalzo J. 2008, New York: Mc Graw-Hill Professional, 2269-2275. 17

Zbar B, Kishida T, Chen F, Schmidt L, Maher ER, Richards FM: Germline mutations in the von Hippel-Lindau disease (VHL) gene in families from North America, Europe, and Japan. Hum Mutat. 1996, 8: 348-357. 10.1002/(SICI)1098-1004(1996)8:4<348::AID-HUMU8>3.0.CO;2-3.CrossRefPubMed

Brown ML, Zayas GE, Abel MD, Young WF, Schaff HV: Mediastinal paragangliomas: the Mayo Clinic experience. Ann Thorac Surg. 2008, 86: 946-951. 10.1016/j.athoracsur.2008.04.105.CrossRefPubMed

Lamy AL, Fradet GJ, Luoma A, Nelems B: Anterior and middle mediastinum paraganglioma: complete resection is the treatment of choice. Ann Thorac Surg. 1994, 57: 249-252. 10.1016/0003-4975(94)90419-7.CrossRefPubMed

Matsumoto J, Nakajima J, Takeuchi E, Fukami T, Nawata K, Takamoto S: Successful perioperative management of a middle mediastinal paraganglioma. J Thorac Cardiovasc Surg. 2006, 132: 705-706. 10.1016/j.jtcvs.2006.02.061.CrossRefPubMed

Title: Superior mediastinal paraganglioma associated with von Hippel-Lindau syndrome: report of a case
Authors: Tsuyoshi Takahashi
Hiroshi Nogimura
Ken Kuriki
Ryo Kobayashi
Publication date: 01-12-2014
Publisher: BioMed Central
Published in: World Journal of Surgical Oncology / Issue 1/2014
Electronic ISSN: 1477-7819
DOI: https://doi.org/10.1186/1477-7819-12-74

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Superior mediastinal paraganglioma associated with von Hippel-Lindau syndrome: report of a case

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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