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AIDS and Behavior
Published in: AIDS and Behavior 10/2021

01-10-2021 | Suicide | Original Paper

Depression and Suicidal Behaviors Among HIV-Infected Inmates in Lesotho: Prevalence, Associated Factors and a Moderated Mediation Model

Authors: Puseletso Martha Mahlomaholo, Huiqi Wang, Yongfeng Xia, Yajun Wang, Xueling Yang, You Wang

Published in: AIDS and Behavior | Issue 10/2021

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Abstract

Depression and suicidal behaviors are two common psychiatric problems observed among people living with HIV. The situation is worse among HIV-infected inmates. The present study aimed to assess the prevalence and associated factors of depression and suicidal behaviors among HIV-infected inmates, and to clarify the mechanisms underlying the impact of HIV-related stigma on suicidal behaviors. The data from 402 HIV-infected inmates in Lesotho showed the prevalence of depression and suicidal behaviors was 53.0% and 8.2%. Female and institution maladaptation were risk factors for depression, and the risk factor for suicidal behaviors was non-participation of institution activities. Moreover, HIV-related stigma indirectly increased inmates’ suicidal behaviors through elevated depression. Such indirect effect was stronger for inmates with a lower level of meaning in life. These findings indicate more concern should be given to high-risk subgroups, and both depression and meaning in life are intervention targets for suicide prevention among HIV-infected inmates.
Footnotes
1
These three correctional institutions are the only institutions with ART centers in Lesotho.
 
Literature
1.
2.
Rubenstein LS, Amon JJ, McLemore M, et al. HIV and related infections in prisoners 4. HIV, prisoners, and human rights. Lancet. 2016;388:1202.PubMedCrossRef
3.
Naidoo S, Mkize DL. Prevalence of mental disorders in a prison population in Durban, South Africa. Afr J Psychiatry (Johannesbg). 2012;15(1):30–5.
4.
Getaneh M, Reta MM, Assefa D, Yohannis Z, Demilew D. Two-third of inmates were depressed among HIV positive prisoners at central prison (Kaliti), Addis Ababa, Ethiopia. BMC Res Notes. 2019;12(1):170.PubMedPubMedCentralCrossRef
5.
Feaster DJ, Reznick OG, Zack B, McCartney K, Gregorich SE, Brincks AM. Health status, sexual and drug risk, and psychosocial factors relevant to postrelease planning for HIV+ prisoners. J Correct Health Care. 2013;19(4):278–92.PubMedCrossRef
6.
Peng EY, Yeh CY, Lyu SY, et al. Prevalence and correlates of lifetime suicidal ideation among HIV-infected male inmates in Taiwan. AIDS Care. 2010;22(10):1212–20.PubMedCrossRef
7.
Han B, Compton WM, Blanco C, Colpe L, Huang L, McKeon R. National trends in the prevalence of suicidal ideation and behavior among young adults and receipt of mental health care among suicidal young adults. J Am Acad Child Adoles Psychiatry. 2018;57(1):20.CrossRef
8.
Scheyett A, Parker S, Golin C, White B, Davis CP, Wohl D. HIV-infected prison inmates: depression and implications for release back to communities. AIDS Behav. 2010;14(2):300–7.PubMedCrossRef
9.
Global Network of People Living with HIV (GNP+) The People Living with HIV Stigma Index. 2019. Secondary the People Living with HIV Stigma Index (2015).
10.
Rueda S, Mitra S, Chen S, et al. Examining the associations between HIV-related stigma and health outcomes in people living with HIV/AIDS: a series of meta-analyses. BMJ Open. 2016;6(7):e011453.PubMedPubMedCentralCrossRef
11.
Ferlatte O, Salway T, Oliffe JL, Trussler T. Stigma and suicide among gay and bisexual men living with HIV. AIDS Care. 2017;29(11):1346–50.PubMedCrossRef
12.
Casale M, Boyes M, Pantelic M, Toska E, Cluver L. Suicidal thoughts and behaviour among South African adolescents living with HIV: can social support buffer the impact of stigma? J Affect Disord. 2019;245:82–90.PubMedCrossRef
13.
Odimegwu CO, Akinyemi JO, Alabi OO. HIV-stigma in Nigeria: review of research studies, policies, and Programmes. AIDS Res Treat. 2017;2017:1–13.CrossRef
14.
Esposito M. “Double burden”: a qualitative study of HIV positive prisoners in Italy. Int J Prison Health. 2012;8(1):35–44.PubMedCrossRef
15.
Culbert GJ, Earnshaw VA, Wulanyani NMS, Wegman MP, Waluyo A, Altice FL. Correlates and experiences of HIV stigma in prisoners living with HIV in Indonesia: a mixed-method analysis. J Assoc Nurses AIDS Care. 2015;26(6):743–57.PubMedPubMedCentralCrossRef
16.
17.
Turan B, Hatcher AM, Weiser SD, Johnson MO, Rice WS, Turan JM. Framing mechanisms linking HIV-related stigma, adherence to treatment, and health outcomes. Am J Public Health. 2017;107(6):863–9.PubMedPubMedCentralCrossRef
18.
Turan B, Rice WS, Crockett KB, et al. Longitudinal association between internalized HIV stigma and antiretroviral therapy adherence for women living with HIV: the mediating role of depression. AIDS. 2019;33(3):571–6.PubMedCrossRef
19.
Turan B, Budhwani H, Fazeli PL, et al. How does stigma affect people living with HIV? The mediating roles of internalized and anticipated HIV stigma in the effects of perceived community stigma on health and psychosocial outcomes. AIDS Behav. 2017;21(1):283–91.PubMedPubMedCentralCrossRef
20.
Zeng C, Li L, Hong YA, et al. A structural equation model of perceived and internalized stigma, depression, and suicidal status among people living with HIV/AIDS. BMC Public Health. 2018;18(1):138.PubMedPubMedCentralCrossRef
21.
Wang W, Wang Y, Xiao C, et al. Psychological pathway to suicidal ideation among people living with HIV/AIDS in China: a structural equation model. Psychiatry Res. 2018;260:255–61.PubMedCrossRef
22.
Steger M, Lopez S. Oxford handbook of positive psychology. New York: Oxford University Press; 2009.
23.
Klonsky ED, May A. The three-step theory (3ST): a new theory of suicide rooted in the “ideation-to-action” framework. Int J Cogn Ther. 2015;8:114–29.CrossRef
24.
Klonsky ED, May AM, Saffer BY. Suicide, suicide attempts, and suicidal ideation. Annu Rev Clin Psychol. 2016;12:307.PubMedCrossRef
25.
Kleiman EM, Beaver JK. A meaningful life is worth living: meaning in life as a suicide resiliency factor. Psychiatry Res. 2013;210(3):934–9.PubMedCrossRef
26.
Costanza A, Baertschi M, Richard-Lepouriel H, Weber K, Pompili M, Canuto A. The presence and the search constructs of meaning in life in suicidal patients attending a psychiatric emergency department. Front Psychiatry. 2020;11:327.PubMedPubMedCentralCrossRef
27.
Marco JH, Cañabate M, Pérez S, Llorca G. Associations among meaning in life, body image, psychopathology, and suicide ideation in Spanish participants with eating disorders. J Clin Psychol. 2017;73(12):1768–81.PubMedCrossRef
28.
Heisel MJ, Flett GL. Purpose in life, satisfaction with life, and suicide ideation in a clinical sample. J Psychopathol Behav Assess. 2004;26(2):127–35.CrossRef
29.
Lu HF, Sheng WH, Liao SC, et al. The changes and the predictors of suicide ideation and suicide attempt among HIV-positive patients at 6–12 months post diagnosis: a longitudinal study. J Adv Nurs. 2019;75(3):573–84.PubMedCrossRef
30.
31.
32.
Smith HJ, Topp SM, Hoffmann CJ, et al. Addressing common mental health disorders among incarcerated people living with HIV: insights from implementation science for service integration and delivery. Curr HIV/AIDS Rep. 2020;17:1–12.CrossRef
33.
Telisinghe L, Charalambous S, Topp SM, et al. HIV and tuberculosis in prisons in sub-Saharan Africa. The Lancet. 2016;388(10050):1215–27.CrossRef
34.
Reinius M, Wettergren L, Wiklander M, Svedhem V, Ekstrom AM, Eriksson LE. Development of a 12-item short version of the HIV stigma scale. Health Qual Life Outcomes. 2017;15(1):115.PubMedPubMedCentralCrossRef
35.
36.
Osman A, Bagge CL, Gutierrez PM, Konick LC, Kopper BA, Barrios FX. The suicidal behaviors questionnaire-revised (SBQ-R): validation with clinical and nonclinical samples. Assessment. 2001;8(4):443–54.PubMedCrossRef
37.
Schulenberg SE, Schnetzer LW, Buchanan EM. The purpose in life test-short form: development and psychometric support. J Happiness Stud. 2011;12(5):861–76.CrossRef
38.
Hayes AF. Introduction to mediation, moderation, and conditional process analysis: a regression-based approach. New York: Guilford Publications; 2017.
39.
Olley BO, Seedat S, Nei DG, Stein DJ. Predictors of major depression in recently diagnosed patients with HIV/AIDS in South Africa. AIDS Patient Care STDS. 2004;18(8):481–7.PubMedCrossRef
40.
Shrestha G, Yadav DK, Sapkota N, et al. Depression among inmates in a regional prison of eastern Nepal: a cross-sectional study. BMC Psychiatry. 2017;17(1):348.PubMedPubMedCentralCrossRef
41.
Uche N, Princewill S. Clinical factors as predictors of depression in a nigerian prison population. J Psychiatry. 2015;19(1):1–6.CrossRef
42.
Crockett MA, Martínez V, Jiménez-Molina Á. Subthreshold depression in adolescence: gender differences in prevalence, clinical features, and associated factors. J Affect Disord. 2020;272:269–76.PubMedCrossRef
43.
Salk RH, Hyde JS, Abramson LY. Gender differences in depression in representative national samples: meta-analyses of diagnoses and symptoms. Psychol Bull. 2017;143(8):783.PubMedPubMedCentralCrossRef
44.
Boothby JL, Durham TW. Screening for depression in prisoners using the beck depression inventory. Crim Justice Behav. 1999;26(1):107–24.CrossRef
45.
Hammen CL. Stress and depression: old questions, new approaches. Curr Opin Psychol. 2015;4:80–5.CrossRef
46.
Caldwell JE, Swan SC, Woodbrown VD. Gender differences in intimate partner violence outcomes. Psychol Violence. 2012;2(1):42.CrossRef
47.
Ahmad A, Mazlan NH. Stress and depression: a comparison study between men and women inmates in Peninsular Malaysia. Int J Hum Soc Sci. 2014;4(2):153–60.
48.
Smyth NJ, Ivanoff A. Maladaptation and prison environmental preferences among inmate parasuicides. J Offender Rehabil. 1994;20(3–4):131–46.CrossRef
49.
Dye MH. Deprivation, importation, and prison suicide: combined effects of institutional conditions and inmate composition. J Crim Just. 2010;38(4):796–806.CrossRef
50.
Esposito M. Women in prison: unhealthy lives and denied well-being between loneliness and seclusion. Crime Law Soc Change. 2015;63(3):137–58.CrossRef
51.
Schappell A, Docherty M, Boxer P. Violence and victimization during incarceration: relations to psychosocial adjustment during reentry to the community. Violence Vict. 2016;31(2):361–78.PubMedCrossRef
52.
Hovenkamp-Hermelink JH, Jeronimus BF, Spinhoven P, Penninx BW, Schoevers RA, Riese H. Differential associations of locus of control with anxiety, depression and life-events: a five-wave, nine-year study to test stability and change. J Affect Disord. 2019;253:26–34.PubMedCrossRef
53.
Erzen E, Çikrikci Ö. The effect of loneliness on depression: a meta-analysis. Int J Soc Psychiatry. 2018;64(5):427–35.PubMedCrossRef
54.
Mgopa LR, Mbwambo J, Likindikoki S, Pallangyo P. Violence and depression among men who have sex with men in Tanzania. BMC Psychiatry. 2017;17(1):1–5.CrossRef
55.
Brown SL, Ireland CA. Coping style and distress in newly incarcerated male adolescents. J Adolesc Health. 2006;38(6):656–61.PubMedCrossRef
56.
Favril L, Laenen FV, Vandeviver C, Audenaert K. Suicidal ideation while incarcerated: prevalence and correlates in a large sample of male prisoners in Flanders, Belgium. Int J Law Psychiatry. 2017;55:19–28.PubMedCrossRef
57.
58.
Berger BE, Ferrans CE, Lashley FR. Measuring stigma in people with HIV: psychometric assessment of the HIV stigma scale. Res Nurs Health. 2001;24(6):518–29.PubMedCrossRef
59.
60.
Logie CH, Marcus N, Wang Y, et al. A longitudinal study of associations between HIV-related stigma, recent violence and depression among women living with HIV in a Canadian cohort study. J Int AIDS Soc. 2019;22(7):e25341.PubMedPubMedCentralCrossRef
61.
Stoliker BE. Attempted suicide: a multilevel examination of inmate characteristics and prison context. Crim Justice Behav. 2018;45:589.CrossRef
62.
Rinehart R, Rao D, Amico RK, et al. Experienced HIV-related stigma and psychological distress in Peruvian sexual and gender minorities: a longitudinal study to explore mediating roles of internalized HIV-related stigma and coping styles. AIDS Behav. 2019;23(3):661–74.PubMedPubMedCentralCrossRef
63.
Earnshaw VA, Smith LR, Chaudoir SR, Amico KR, Copenhaver MM. HIV stigma mechanisms and well-being among PLWH: a test of the HIV stigma framework. AIDS Behav. 2013;17(5):1785–95.PubMedPubMedCentralCrossRef
64.
Vance DE, Moneyham L, Fordham P, Struzick TC. A model of suicidal ideation in adults aging with HIV. J Assoc Nurses AIDS Care. 2008;19(5):375–84.PubMedCrossRef
65.
Zhou SG, Hou YF, Liu D, Zhang XY. Effect of cognitive behavioral therapy versus interpersonal psychotherapy in patients with major depressive disorder: a meta-analysis of randomized controlled Trials. Chin Med J. 2017;130(23):2844–51.PubMedPubMedCentralCrossRef
66.
Carrico AW. Elevated suicide rate among HIV-positive persons despite benefits of antiretroviral therapy: implications for a stress and coping model of suicide. Am J Psychiatry. 2010;167(2):117–9.PubMedCrossRef
67.
Park CL. Making sense of the meaning literature: an integrative review of meaning making and its effects on adjustment to stressful life events. Psychol Bull. 2010;136(2):257–301.PubMedCrossRef
68.
Rivkin ID, Gustafson J, Weingarten I, Chin D. The effects of expressive writing on adjustment to HIV. AIDS Behav. 2006;10(1):13–26.PubMedCrossRef
69.
Culbert GJ. Violence and the perceived risks of taking antiretroviral therapy in US jails and prisons. International Journal of Prisoner Health. 2014.
70.
Ellis R. Prisons as porous institutions. Theory and Society. 2021:1–25.
71.
Vanhooren S, Leijssen M, Dezutter J. Coping strategies and posttraumatic growth in prison. The Prison Journal. 2018;98(2):123–42.CrossRef
72.
Vanhooren S, Leijssen M, Dezutter J. Loss of meaning as a predictor of distress in prison. Int J Offender Ther Comp Criminol. 2017;61(13):1411–32.PubMedCrossRef
73.
Russell S, Martin F, Zalwango F, et al. Finding meaning: HIV self-management and wellbeing among people taking antiretroviral therapy in Uganda. PloS ONE. 2016;11 (1):e0147896.
74.
Perrin C, Blagden N. Accumulating meaning, purpose and opportunities to change ‘drip by drip’: the impact of being a listener in prison. Psychology, Crime & Law. 2014;20(9):902–20.CrossRef
Metadata
Title
Depression and Suicidal Behaviors Among HIV-Infected Inmates in Lesotho: Prevalence, Associated Factors and a Moderated Mediation Model
Authors
Puseletso Martha Mahlomaholo
Huiqi Wang
Yongfeng Xia
Yajun Wang
Xueling Yang
You Wang
Publication date
01-10-2021
Publisher
Springer US
Published in
AIDS and Behavior / Issue 10/2021
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-021-03330-9

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