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Open Access 01-12-2021 | Subarachnoid Hemorrhage | Research

Weather conditions associated with subarachnoid hemorrhage: a multicenter case-crossover study

Authors: Michael Kockler, Peter Schlattmann, Mario Walther, Georg Hagemann, Philipp Nils Becker, Steffen Rosahl, Otto W. Witte, Matthias Schwab, Florian Rakers

Published in: BMC Neurology | Issue 1/2021

Abstract

Background

Most spontaneous subarachnoid hemorrhages (SAH) occur unexpectedly and independently of classical risk factors. In the light of increasing climate variability and change, we investigated weather and rapid weather changes as possible short-term risk factors for SAH.

Methods

Seven hundred ninety one patients admitted to three major hospitals in Germany for non-traumatic SAH with a determinable onset of SAH symptoms were included in this hospital-based, case-crossover study. The effects of atmospheric pressure, relative air humidity, and ambient temperature and their 24 h changes on the onset of SAH under temperate climate conditions were estimated.

Results

There was no association between the risk of SAH and 24 h weather changes, mean daily temperature or mean relative air humidity in the overall population. For every 11.5 hPa higher mean daily atmospheric pressure, the risk of SAH increased by 15% (OR 1.15, 95% confidence interval (CI) 1.01–1.30) in the entire study population with a lag time of three days.

Conclusion

Our results suggest no relevant association between 24 h-weather changes or absolute values of ambient temperature and relative humidity and the risk of SAH. The medical significance of the statistically weak increase in SAH risk three days after exposure to high atmospheric pressure is unclear. However, as the occurrence of stable high-pressure systems will increase with global warming and potentially affect SAH risk, we call for confirming studies in different geographical regions to verify our observations.

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Title: Weather conditions associated with subarachnoid hemorrhage: a multicenter case-crossover study
Authors: Michael Kockler
Peter Schlattmann
Mario Walther
Georg Hagemann
Philipp Nils Becker
Steffen Rosahl
Otto W. Witte
Matthias Schwab
Florian Rakers
Publication date: 01-12-2021
Publisher: BioMed Central
Keywords: Subarachnoid Hemorrhage
Subarachnoid Hemorrhage
Published in: BMC Neurology / Issue 1/2021
Electronic ISSN: 1471-2377
DOI: https://doi.org/10.1186/s12883-021-02312-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Weather conditions associated with subarachnoid hemorrhage: a multicenter case-crossover study

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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