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Published in: BMC Neurology 1/2020

Open Access 01-12-2020 | Stroke | Research article

Risk factors affecting the 1-year outcomes of minor ischemic stroke: results from Xi’an stroke registry study of China

Authors: Zhongzhong Liu, Wenjuan Lin, Qingli Lu, Jing Wang, Pei Liu, Xuemei Lin, Fang Wang, Yaling Shi, Qing Wang, Guozheng Liu, Songdi Wu

Published in: BMC Neurology | Issue 1/2020

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Abstract

Background

The prevalence of stroke recurrence, disability, and all-cause mortality of patients with minor ischemic stroke (MIS) remains problematic. The aim of the present study was to identify risk factors associated with adverse outcomes at 1 year after MIS in the Xi’an region of China.

Methods

This prospective cohort study included MIS patients above 18 years old with National Institutes of Health Stroke Scale (NIHSS) score ≤ 3 who were treated in any of four hospitals in Xi’an region of China between January and December 2015. The 1-year prevalence of stroke recurrence, disability, and all-cause mortality were evaluated, respectively. Multivariate logistic regression analysis was performed to assess the association between the identified risk factors and clinical outcomes.

Results

In this study, 131(10.5%, 131/1252) patients were lost to follow-up at 1 year. A total of 1121 patients were included for analysis, the prevalence of stroke recurrence, disability, and all-cause mortality at 1 year after MIS were 3.4% (38/1121), 9.3% (104/1121), and 3.3% (37/1121), respectively. Multivariate logistic regression analysis identified age, current smoking, and pneumonia as independent risk factors for stroke recurrence. Age, pneumonia, and alkaline phosphatase were independent risk factors for all-cause mortality. Independent risk factors for disability were age, pneumonia, NIHSS score on admission, and leukocyte count.

Conclusions

The 1-year outcomes of MIS in Xi’an region of China were not optimistic, especially with a high prevalence of disability. The present study indicated that age and pneumonia were the common independent risk factors affecting the 1-year outcomes of MIS in Xi’an region of China.
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Metadata
Title
Risk factors affecting the 1-year outcomes of minor ischemic stroke: results from Xi’an stroke registry study of China
Authors
Zhongzhong Liu
Wenjuan Lin
Qingli Lu
Jing Wang
Pei Liu
Xuemei Lin
Fang Wang
Yaling Shi
Qing Wang
Guozheng Liu
Songdi Wu
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Neurology / Issue 1/2020
Electronic ISSN: 1471-2377
DOI
https://doi.org/10.1186/s12883-020-01954-3

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