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Open Access 01-12-2015 | Research article

Factors for short-term outcomes in patients with a minor stroke: results from China National Stroke Registry

Authors: Lingyun Wu, Anxin Wang, Xianwei Wang, Xingquan Zhao, Chunxue Wang, Liping Liu, Huaguang Zheng, Yongjun Wang, Yibin Cao, Yilong Wang, on behalf of the China National Stroke Registry investigators

Published in: BMC Neurology | Issue 1/2015

Abstract

Background

Stroke recurrence and disability in patients with a minor stroke is one of the most depressing medical situations. In this study, we aimed to identify which factors were associated with adverse outcomes of a minor stroke.

Methods

The China National Stroke Registry (CNSR) is a nationwide prospective registry for patients presented to hospitals with acute cerebrovascular events between September 2007 and August 2008. The 3-month follow-up was completed in 4669 patients with a minor stroke defined as the initial neurological severity lower than 4 in the National Institutes of Health Stroke Scale (NIHSS). Multivariate model was used to determine the association between risk factors and clinical outcomes.

Results

Of 4669 patients with a minor stroke during 3-month follow-up, 459 (9.8 %) patients experienced recurrent stroke, 679 (14.5 %) had stroke disability and 168 (3.6 %) died. Multivariate model identified hypertension, diabetes mellitus, atrial fibrillation, coronary heart disease and previous stroke as independent predictors for the recurrent stroke. Age, diabetes mellitus, atrial fibrillation, previous stroke and time from onset to admission < 24 h were independent predictors for stroke disability. The independent predictors for the all-caused death were age, atrial fibrillation, and coronary heart disease.

Conclusions

The short-term risk of poor clinical outcome in Chinese patients with a minor stroke was substantial. Therefore, patients with a minor stroke should be given expeditious assessment and urgent aggressive intervention.

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Title: Factors for short-term outcomes in patients with a minor stroke: results from China National Stroke Registry
Authors: Lingyun Wu
Anxin Wang
Xianwei Wang
Xingquan Zhao
Chunxue Wang
Liping Liu
Huaguang Zheng
Yongjun Wang
Yibin Cao
Yilong Wang
on behalf of the China National Stroke Registry investigators
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: BMC Neurology / Issue 1/2015
Electronic ISSN: 1471-2377
DOI: https://doi.org/10.1186/s12883-015-0505-z

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Factors for short-term outcomes in patients with a minor stroke: results from China National Stroke Registry

Abstract

Background

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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