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Journal of Thrombosis and Thrombolysis
Published in: Journal of Thrombosis and Thrombolysis 2/2020

01-08-2020 | Stroke

Antithrombotic therapy for atrial fibrillation with stable coronary artery disease: a meta-analysis of randomized controlled trials

Authors: Babikir Kheiri, Timothy F. Simpson, Eric C. Stecker, Mohammed Osman, Hind Rahmouni, Firas Zahr, Babak Nazer, Joaquin E. Cigarroa

Published in: Journal of Thrombosis and Thrombolysis | Issue 2/2020

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Excerpt

  • Oral anticoagulation (OAC) is associated with similar efficacy rates as combination therapy.
  • Lower bleeding risk is observed with OAC monotherapy.
…
Literature
1.
Yasuda S, Kaikita K, Akao M et al (2019) Antithrombotic therapy for atrial fibrillation with stable coronary disease. N Engl J Med 381(12):1103–1113CrossRef
2.
Kheiri B, Osman M, Bakhit A et al (2019) Dual versus triple therapy for patients with atrial fibrillation and acute coronary syndrome: a meta-analysis and trial sequential analysis of randomized controlled trials. J Thromb Thrombolysis 48(3):511–513CrossRef
3.
Mehta S, Bainey K, Cantor W et al (2018) 2018 Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology focused update of the guidelines for the use of antiplatelet therapy. Can J Cardiol 34:214–233CrossRef
4.
Valgimigli M, Bueno H, Byrne R et al (2018) 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS: the Task Force for dual antiplatelet therapy in coronary artery disease of the European Society of Cardiology (ESC) and of the European. Eur Hear J 39:213–260CrossRef
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Matsumura-Nakano Y, Shizuta S, Komasa A et al (2019) Open-label randomized trial comparing oral anticoagulation with and without single antiplatelet therapy in patients with atrial fibrillation and stable coronary artery disease beyond 1 year after coronary stent implantation: OAC-ALONE study. Circulation 139:604–616CrossRef
6.
Osman M, Kheiri B, Munir M et al (2019) The fading role of triple therapy in patients with atrial fibrillation and acute coronary syndrome: a Bayesian network meta-analysis. J Thromb Thrombolysis 48(3):516–518CrossRef
7.
Lamberts M, Gislason G, Lip G et al (2014) Antiplatelet therapy for stable coronary artery disease in atrial fibrillation patients taking an oral anticoagulant: a nationwide cohort study. Circulation 129:1577–1585CrossRef
8.
van Rein N, Heide-Jørgensen U, Lijfering W et al (2019) Major bleeding rates in atrial fibrillation patients on single, dual, or triple antithrombotic therapy. Circulation 139:775–786CrossRef
Metadata
Title
Antithrombotic therapy for atrial fibrillation with stable coronary artery disease: a meta-analysis of randomized controlled trials
Authors
Babikir Kheiri
Timothy F. Simpson
Eric C. Stecker
Mohammed Osman
Hind Rahmouni
Firas Zahr
Babak Nazer
Joaquin E. Cigarroa
Publication date
01-08-2020
Publisher
Springer US
Published in
Journal of Thrombosis and Thrombolysis / Issue 2/2020
Print ISSN: 0929-5305
Electronic ISSN: 1573-742X
DOI
https://doi.org/10.1007/s11239-020-02041-7

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At a glance: The STEP trials

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A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

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