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Published in: Current Urology Reports 11/2019

01-11-2019 | Stress Incontinence | Lower Urinary Tract Symptoms & Voiding Dysfunction (J Sandhu, Section Editor)

Neobladder-Vaginal Fistula: Surgical Management Techniques

Author: Melissa R. Kaufman

Published in: Current Urology Reports | Issue 11/2019

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Abstract

Purpose of Review

To describe the complexities of diagnosis and management of neobladder-vaginal fistula (NVF) following orthotopic urinary diversion in women.

Recent Findings

Multiple recent single-institution series confirm the variability of outcomes for NVF repairs and caution regarding comorbid stress urinary incontinence which may necessitate further interventions including conversion to alternate diversions.

Summary

Although both abdominal and transvaginal approaches have been advocated for surgical management of NVF, contemporary series from reconstructive surgeons favor a vaginal approach to decrease overall operative morbidity. Patients should be carefully counseled regarding neobladder and sphincter function following fistula repair along with the risks of secondary urinary diversion.
Literature
1.
go back to reference Siegel RL, Miller KD, Jemal A. Cancer statistics, 2018. CA Cancer J Clin. 2018;68(1):7–30.PubMed Siegel RL, Miller KD, Jemal A. Cancer statistics, 2018. CA Cancer J Clin. 2018;68(1):7–30.PubMed
2.
go back to reference •• Chang SS, Bochner BH, Chou R, Dreicer R, Kamat AM, Lerner SP, et al. Treatment of non-metastatic muscle-invasive bladder cancer: AUA/ASCO/ASTRO/SUO Guideline. J Urol. 2017;198(4):552–9 Critical guideline for evaluation and management of muscle-invasive bladder malignancy. CrossRefPubMedPubMedCentral •• Chang SS, Bochner BH, Chou R, Dreicer R, Kamat AM, Lerner SP, et al. Treatment of non-metastatic muscle-invasive bladder cancer: AUA/ASCO/ASTRO/SUO Guideline. J Urol. 2017;198(4):552–9 Critical guideline for evaluation and management of muscle-invasive bladder malignancy. CrossRefPubMedPubMedCentral
3.
go back to reference Hautmann RE, Abol-Enein H, Davidsson T, Gudjonsson S, Hautmann SH, Holm HV, et al. ICUD–EAU international consultation on bladder cancer 2012: urinary diversion. Eur Urol. 2013;63(1):67–80.CrossRefPubMed Hautmann RE, Abol-Enein H, Davidsson T, Gudjonsson S, Hautmann SH, Holm HV, et al. ICUD–EAU international consultation on bladder cancer 2012: urinary diversion. Eur Urol. 2013;63(1):67–80.CrossRefPubMed
4.
go back to reference Gakis G, Stenzl A. Considerations for orthotopic diversions in women. Curr Opin Urol. 2015;25(6):550–4.CrossRefPubMed Gakis G, Stenzl A. Considerations for orthotopic diversions in women. Curr Opin Urol. 2015;25(6):550–4.CrossRefPubMed
5.
go back to reference Gakis G, Jentzmik F, Schrader M, Stenzl A, Sievert KD. Benefits and risks of orthotopic neobladder reconstruction in female patients. Aktuelle Urol. 2011;42(2):109–14.CrossRefPubMed Gakis G, Jentzmik F, Schrader M, Stenzl A, Sievert KD. Benefits and risks of orthotopic neobladder reconstruction in female patients. Aktuelle Urol. 2011;42(2):109–14.CrossRefPubMed
6.
go back to reference Smith AB, Crowell K, Woods ME, Wallen EM, Pruthi RS, Nielsen ME, et al. Functional outcomes following radical cystectomy in women with bladder cancer: a systematic review. Eur Urol Focus. 2017;3(1):136–43.CrossRefPubMed Smith AB, Crowell K, Woods ME, Wallen EM, Pruthi RS, Nielsen ME, et al. Functional outcomes following radical cystectomy in women with bladder cancer: a systematic review. Eur Urol Focus. 2017;3(1):136–43.CrossRefPubMed
7.
go back to reference Stenzl A, Nagele U, Kuczyk M, et al. Cystectomy-technical considerations in male and female patients. EAU Updat Ser. 2005;3(3):138–46.CrossRef Stenzl A, Nagele U, Kuczyk M, et al. Cystectomy-technical considerations in male and female patients. EAU Updat Ser. 2005;3(3):138–46.CrossRef
8.
go back to reference Veskimae E, Neuzillet Y, Rouanne M, MacLennan S, Lam TBL, Yuan Y, et al. Systematic review of the oncological and functional outcomes of pelvic organ-preserving radical cystectomy (RC) compared with standard RC in women who undergo curative surgery and orthotopic neobladder substitution for bladder cancer. BJU Int. 2017;120(1):12–24.CrossRefPubMed Veskimae E, Neuzillet Y, Rouanne M, MacLennan S, Lam TBL, Yuan Y, et al. Systematic review of the oncological and functional outcomes of pelvic organ-preserving radical cystectomy (RC) compared with standard RC in women who undergo curative surgery and orthotopic neobladder substitution for bladder cancer. BJU Int. 2017;120(1):12–24.CrossRefPubMed
9.
go back to reference •• Zlatev DV, Skinner EC. Orthotopic urinary diversion for women. Urol Clin North Am. 2018;45(1):49–54 Outstanding synopsis of technical considerations during radical cystectomy which may limit eventual functional and anatomic complications. CrossRefPubMed •• Zlatev DV, Skinner EC. Orthotopic urinary diversion for women. Urol Clin North Am. 2018;45(1):49–54 Outstanding synopsis of technical considerations during radical cystectomy which may limit eventual functional and anatomic complications. CrossRefPubMed
10.
go back to reference Chang SS, Cole E, Cookson MS, Peterson M, Smith JA Jr. Preservation of the anterior vaginal wall during female radical cystectomy with orthotopic urinary diversion: technique and results. J Urol. 2002;168(4 Pt 1):1442–5.CrossRefPubMed Chang SS, Cole E, Cookson MS, Peterson M, Smith JA Jr. Preservation of the anterior vaginal wall during female radical cystectomy with orthotopic urinary diversion: technique and results. J Urol. 2002;168(4 Pt 1):1442–5.CrossRefPubMed
11.
go back to reference Ali-El-Dein B, Mosbah A, Osman Y, El-Tabey N, Abdel-Latif M, Eraky I, et al. Preservation of the internal genital organs during radical cystectomy in selected women with bladder cancer: a report on 15 cases with long term follow-up. Eur J Surg Oncol. 2013;39(4):358–64.CrossRefPubMed Ali-El-Dein B, Mosbah A, Osman Y, El-Tabey N, Abdel-Latif M, Eraky I, et al. Preservation of the internal genital organs during radical cystectomy in selected women with bladder cancer: a report on 15 cases with long term follow-up. Eur J Surg Oncol. 2013;39(4):358–64.CrossRefPubMed
12.
go back to reference Skinner EC, Comiter CV. Can we improve the functional outcomes of orthotopic diversion in women? Eur Urol. 2015;68(4):672–3.CrossRefPubMed Skinner EC, Comiter CV. Can we improve the functional outcomes of orthotopic diversion in women? Eur Urol. 2015;68(4):672–3.CrossRefPubMed
13.
go back to reference •• Carmel ME, Goldman HB, Moore CK, Rackley RR, Vasavada SP. Transvaginal neobladder vaginal fistula repair after radical cystectomy with orthotopic urinary diversion in women. Neurourol Urodyn. 2016;35(1):90–4 Superior synopsis of large series of neobladder-vaginal fistula repairs utilizing a transvaginal approach. Excellent review of both center outcomes and available literature. CrossRefPubMed •• Carmel ME, Goldman HB, Moore CK, Rackley RR, Vasavada SP. Transvaginal neobladder vaginal fistula repair after radical cystectomy with orthotopic urinary diversion in women. Neurourol Urodyn. 2016;35(1):90–4 Superior synopsis of large series of neobladder-vaginal fistula repairs utilizing a transvaginal approach. Excellent review of both center outcomes and available literature. CrossRefPubMed
14.
go back to reference • Littlejohn N, Cohn JA, Kowalik CG, Kaufman MR, Dmochowski RR, Reynolds WS. Treatment of pelvic floor disorders following neobladder. Curr Urol Rep. 2017;18(1):5. Excellent review of contemproary literature on functional outcomes from orthotopic diversion. CrossRefPubMed • Littlejohn N, Cohn JA, Kowalik CG, Kaufman MR, Dmochowski RR, Reynolds WS. Treatment of pelvic floor disorders following neobladder. Curr Urol Rep. 2017;18(1):5. Excellent review of contemproary literature on functional outcomes from orthotopic diversion. CrossRefPubMed
15.
go back to reference Gelber K, Bohrer J, Kim CO, Minaglia S. Vaginal repair of neobladder-vaginal fistula: a case report and review of the literature. Int Urogynecol J. 2013;24(1):175–8.CrossRefPubMed Gelber K, Bohrer J, Kim CO, Minaglia S. Vaginal repair of neobladder-vaginal fistula: a case report and review of the literature. Int Urogynecol J. 2013;24(1):175–8.CrossRefPubMed
16.
go back to reference Rapp DE, O'Connor RC, Katz EE, Steinberg GD. Neobladder-vaginal fistula after cystectomy and orthotopic neobladder construction. BJU Int. 2004;94(7):1092–5 discussion 5.CrossRefPubMed Rapp DE, O'Connor RC, Katz EE, Steinberg GD. Neobladder-vaginal fistula after cystectomy and orthotopic neobladder construction. BJU Int. 2004;94(7):1092–5 discussion 5.CrossRefPubMed
17.
go back to reference Gschwend JE, May F, Paiss T, Gottfried HW, Hautmann RE. High-dose pelvic irradiation followed by ileal neobladder urinary diversion: complications and long-term results. Br J Urol. 1996;77(5):680–3.CrossRefPubMed Gschwend JE, May F, Paiss T, Gottfried HW, Hautmann RE. High-dose pelvic irradiation followed by ileal neobladder urinary diversion: complications and long-term results. Br J Urol. 1996;77(5):680–3.CrossRefPubMed
18.
go back to reference Ali-el-Dein B, Shaaban AA, Abu-Eideh RH, el-Azab M, Ashamallah A, Ghoneim MA. Surgical complications following radical cystectomy and orthotopic neobladders in women. J Urol. 2008;180(1):206–10 discussion 10.CrossRefPubMed Ali-el-Dein B, Shaaban AA, Abu-Eideh RH, el-Azab M, Ashamallah A, Ghoneim MA. Surgical complications following radical cystectomy and orthotopic neobladders in women. J Urol. 2008;180(1):206–10 discussion 10.CrossRefPubMed
19.
go back to reference Bailey GC, Blackburne A, Ziegelmann MJ, Lightner DJ. Outcomes of surgical management in patients with stress urinary incontinence and/or neovesicovaginal fistula after orthotopic neobladder diversion. J Urol. 2016;196(5):1478–83.CrossRefPubMed Bailey GC, Blackburne A, Ziegelmann MJ, Lightner DJ. Outcomes of surgical management in patients with stress urinary incontinence and/or neovesicovaginal fistula after orthotopic neobladder diversion. J Urol. 2016;196(5):1478–83.CrossRefPubMed
20.
go back to reference Pruthi RS, Petrus CD, Bundrick WJ. New onset vesicovaginal fistula after transurethral collagen injection in women who underwent cystectomy and orthotopic neobladder creation: presentation and definitive treatment. J Urol. 2000;164(5):1638–9.CrossRefPubMed Pruthi RS, Petrus CD, Bundrick WJ. New onset vesicovaginal fistula after transurethral collagen injection in women who underwent cystectomy and orthotopic neobladder creation: presentation and definitive treatment. J Urol. 2000;164(5):1638–9.CrossRefPubMed
21.
go back to reference Tunuguntla HS, Manoharan M, Gousse AE. Management of neobladder-vaginal fistula and stress incontinence following radical cystectomy in women: a review. World J Urol. 2005;23(4):231–5.CrossRefPubMed Tunuguntla HS, Manoharan M, Gousse AE. Management of neobladder-vaginal fistula and stress incontinence following radical cystectomy in women: a review. World J Urol. 2005;23(4):231–5.CrossRefPubMed
22.
go back to reference Selli C, De Maria M, Manica M, Turri FM, Manassero F. Minimally invasive treatment of urinary fistulas using N-butyl-2-cyanoacrylate: a valid first line option. BMC Urol. 2013;13:55.CrossRefPubMedPubMedCentral Selli C, De Maria M, Manica M, Turri FM, Manassero F. Minimally invasive treatment of urinary fistulas using N-butyl-2-cyanoacrylate: a valid first line option. BMC Urol. 2013;13:55.CrossRefPubMedPubMedCentral
23.
go back to reference Morita T, Tachikawa N, Tokue A. Successful closure of neovesicocutaneous fistula with fibrin glue. Urol Int. 1998;61(2):130–1.CrossRefPubMed Morita T, Tachikawa N, Tokue A. Successful closure of neovesicocutaneous fistula with fibrin glue. Urol Int. 1998;61(2):130–1.CrossRefPubMed
24.
go back to reference Rosenberg S, Miranda G, Ginsberg DA. Neobladder-vaginal fistula: the University of Southern California experience. Neurourol Urodyn. 2018;37(4):1380–5.CrossRefPubMed Rosenberg S, Miranda G, Ginsberg DA. Neobladder-vaginal fistula: the University of Southern California experience. Neurourol Urodyn. 2018;37(4):1380–5.CrossRefPubMed
25.
go back to reference Ali-El-Dein B, Ashamallah A. Vaginal repair of pouch-vaginal fistula after orthotopic bladder substitution in women. Urology. 2013;81(1):198–202.CrossRefPubMed Ali-El-Dein B, Ashamallah A. Vaginal repair of pouch-vaginal fistula after orthotopic bladder substitution in women. Urology. 2013;81(1):198–202.CrossRefPubMed
26.
go back to reference Alcantara-Quispe C, Machado RD, Magnabosco WJ, Santos AC, Faria EF. Neovagina construction and continent cutaneous urinary reservoir using a previous orthotopic ileal neobladder. Int Braz J Urol. 2018;44(5):1036–41.CrossRefPubMed Alcantara-Quispe C, Machado RD, Magnabosco WJ, Santos AC, Faria EF. Neovagina construction and continent cutaneous urinary reservoir using a previous orthotopic ileal neobladder. Int Braz J Urol. 2018;44(5):1036–41.CrossRefPubMed
27.
go back to reference Hautmann RE, de Petriconi R, Schwarz J, Volkmer B. Single center experience with secondary urinary diversion after initial radical cystectomy and primary urinary diversion. J Urol. 2016;195(2):406–12.CrossRefPubMed Hautmann RE, de Petriconi R, Schwarz J, Volkmer B. Single center experience with secondary urinary diversion after initial radical cystectomy and primary urinary diversion. J Urol. 2016;195(2):406–12.CrossRefPubMed
Metadata
Title
Neobladder-Vaginal Fistula: Surgical Management Techniques
Author
Melissa R. Kaufman
Publication date
01-11-2019
Publisher
Springer US
Published in
Current Urology Reports / Issue 11/2019
Print ISSN: 1527-2737
Electronic ISSN: 1534-6285
DOI
https://doi.org/10.1007/s11934-019-0934-0

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