Published in:
01-11-2019 | Overactive Bladder | Lower Urinary Tract Symptoms & Voiding Dysfunction (J Sandhu, Section Editor)
Management Strategies for Nocturia
Authors:
Danielle J. Gordon, Curran J. Emeruwa, Jeffrey P. Weiss
Published in:
Current Urology Reports
|
Issue 11/2019
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Abstract
Purpose of Review
Nocturia is defined as awakening due to the desire to void during a period of intended sleep. The pathophysiology of nocturia is multifactorial and management remains a challenge. Herein, we provide an overview of the management strategies for nocturia and summarize the existing evidence for treatment of nocturia across the condition’s broad etiologic categories: nocturnal polyuria, diminished bladder capacity, and global polyuria.
Recent Findings
Treatment should begin with behavioral modification. A high level of evidence supports the efficacy of desmopressin in the treatment of nocturnal polyuria. Data supporting the efficacy of α-blockers, antimuscarinics, and surgical bladder outlet procedures in the treatment of nocturia remains limited.
Summary
Treatment options for nocturia are determined by underlying mechanism. Desmopressin is effective in treating nocturnal polyuria. Surgical intervention, α-blockers, and antimuscarinics may improve nocturia when associated with lower urinary tract symptoms or overactive bladder in the setting of diminished bladder capacity.