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Published in: Pediatric Cardiology 3/2014

01-03-2014 | Original Article

Stenting of the Right Ventricular Outflow Tract in the High-Risk Infant With Cyanotic Teratology of Fallot

Authors: Chesney D. Castleberry, Todd M. Gudausky, Stuart Berger, James S. Tweddell, Andrew N. Pelech

Published in: Pediatric Cardiology | Issue 3/2014

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Abstract

Neonatal tetralogy of Fallot (TOF) repair carries an increased risk of low birthweight or premature infants. Studies are investigating stents in the right ventricular outflow tract (RVOT) as an alternative to aortopulmonary shunts. The authors review their institutional experience with RVOT stenting in the high-risk infant with TOF. Data on sequential patients who received RVOT stents were reviewed, with collection of their surgical, echocardiographic, and catheterization data. Size-matched control subjects were identified and outcomes compared. Six infants went to the catheterization lab for RVOT stenting from 2008 to 2010. Five of these patients had placement of an RVOT stent after balloon dilation. The median saturations were 71 % on 48 % fraction of inspired oxygen (FiO2), with improvement to 94 % (p < 0.001) on 39 % FiO2 24 h after stent placement. As shown by echocardiography, the diameter of the median right pulmonary artery (RPA) was 2.6 mm (z-score, −3.3), and the diameter of the left pulmonary artery (LPA) was 2.0 mm (z-score, −4.5). Repeat echocardiography before surgery showed a statistically significant increase in RPA and LPA size as well as a modified McGoon ratio (p < 0.05). Four of the five patients subsequently underwent TOF repair. No stent fractures occurred. One patient had repair 10 days after stent placement secondary to stent malposition and tricuspid valve injury. The authors’ experience with stents in the RVOT of TOF patients has yielded good results, with significant improvement in oxygen saturations. Patients had successful elective surgical repair and stent removal without longer cardiopulmonary bypass times or recognizable complications compared with shunted patients.
Literature
1.
go back to reference Ahmad U, Fatimi SH, Naqvi I, Atiq M, Moizuddin SS, Sheikh KB, Shahbuddin S, Naseem TM, Javed MA (2008) Modified Blalock–Taussig shunt: immediate and short-term follow-up results in neonates. Heart Lung Circ 17:54–58. doi:10.1016/j.hlc.2007.06.003 S1443-9506(07)00274-0 [pii]CrossRefPubMed Ahmad U, Fatimi SH, Naqvi I, Atiq M, Moizuddin SS, Sheikh KB, Shahbuddin S, Naseem TM, Javed MA (2008) Modified Blalock–Taussig shunt: immediate and short-term follow-up results in neonates. Heart Lung Circ 17:54–58. doi:10.​1016/​j.​hlc.​2007.​06.​003 S1443-9506(07)00274-0 [pii]CrossRefPubMed
2.
go back to reference Alwi M, Choo KK, Latiff HA, Kandavello G, Samion H, Mulyadi MD (2004) Initial results and medium-term follow-up of stent implantation of patent ductus arteriosus in duct-dependent pulmonary circulation. J Am Coll Cardiol 44:438–445. doi:10.1016/j.jacc.2004.03.066 CrossRefPubMed Alwi M, Choo KK, Latiff HA, Kandavello G, Samion H, Mulyadi MD (2004) Initial results and medium-term follow-up of stent implantation of patent ductus arteriosus in duct-dependent pulmonary circulation. J Am Coll Cardiol 44:438–445. doi:10.​1016/​j.​jacc.​2004.​03.​066 CrossRefPubMed
3.
go back to reference Casaccia G, Crescenzi F, Dotta A, Capolupo I, Braguglia A, Danhaive O, Pasquini L, Bevilacqua M, Bagolan P, Corchia C (2006) Birth weight and McGoon Index predict mortality in newborn infants with congenital diaphragmatic hernia. J Pediatr Surg 41:25–28. doi:10.1016/j.jpedsurg.2005.10.002 CrossRefPubMed Casaccia G, Crescenzi F, Dotta A, Capolupo I, Braguglia A, Danhaive O, Pasquini L, Bevilacqua M, Bagolan P, Corchia C (2006) Birth weight and McGoon Index predict mortality in newborn infants with congenital diaphragmatic hernia. J Pediatr Surg 41:25–28. doi:10.​1016/​j.​jpedsurg.​2005.​10.​002 CrossRefPubMed
4.
go back to reference Chang AC, Hanley FL, Lock JE, Castaneda AR, Wessel DL (1994) Management and outcome of low-birth-weight neonates with congenital heart disease. J Pediatr 124:461–466 S0022347694003859 [pii]CrossRefPubMed Chang AC, Hanley FL, Lock JE, Castaneda AR, Wessel DL (1994) Management and outcome of low-birth-weight neonates with congenital heart disease. J Pediatr 124:461–466 S0022347694003859 [pii]CrossRefPubMed
5.
6.
go back to reference Dryzek P, Mazurek-Kula A, Moszura T, Sysa A (2008) Right ventricle outflow tract stenting as a method of palliative treatment of severe tetralogy of Fallot. Cardiol J 15:376–379PubMed Dryzek P, Mazurek-Kula A, Moszura T, Sysa A (2008) Right ventricle outflow tract stenting as a method of palliative treatment of severe tetralogy of Fallot. Cardiol J 15:376–379PubMed
10.
go back to reference Gedicke M, Morgan G, Parry A, Martin R, Tulloh R (2010) Risk factors for acute shunt blockage in children after modified Blalock–Taussig shunt operations. Heart Vessel 25:405–409. doi:10.1007/s00380-009-1219-1 CrossRef Gedicke M, Morgan G, Parry A, Martin R, Tulloh R (2010) Risk factors for acute shunt blockage in children after modified Blalock–Taussig shunt operations. Heart Vessel 25:405–409. doi:10.​1007/​s00380-009-1219-1 CrossRef
11.
go back to reference Kirklin JW, Blackstone EH, Pacifico AD, Brown RN, Bargeron LM Jr (1979) Routine primary repair vs two-stage repair of tetralogy of Fallot. Circulation 60:373–386CrossRefPubMed Kirklin JW, Blackstone EH, Pacifico AD, Brown RN, Bargeron LM Jr (1979) Routine primary repair vs two-stage repair of tetralogy of Fallot. Circulation 60:373–386CrossRefPubMed
13.
14.
go back to reference Lee C, Lee CN, Kim SC, Lim C, Chang YH, Kang CH, Jo WM, Kim WH (2006) Outcome after one-stage repair of tetralogy of Fallot. J Cardiovasc Surg Torino 47:65–70PubMed Lee C, Lee CN, Kim SC, Lim C, Chang YH, Kang CH, Jo WM, Kim WH (2006) Outcome after one-stage repair of tetralogy of Fallot. J Cardiovasc Surg Torino 47:65–70PubMed
15.
go back to reference McMahon CJ, Walsh KP (2013) Transcatheter right ventricular outflow tract stent implantation in a child with pentalogy of Cantrell, double-outlet right ventricle, and severe pulmonary stenosis: catheterization and cardiovascular interventions. J Soc Card Angiogr Interv. doi:10.1002/ccd.24852 McMahon CJ, Walsh KP (2013) Transcatheter right ventricular outflow tract stent implantation in a child with pentalogy of Cantrell, double-outlet right ventricle, and severe pulmonary stenosis: catheterization and cardiovascular interventions. J Soc Card Angiogr Interv. doi:10.​1002/​ccd.​24852
16.
go back to reference Pacifico AD, Bargeron LM Jr, Kirklin JW (1973) Primary total correction of tetralogy of Fallot in children less than four years of age. Circulation 48:1085–1091CrossRefPubMed Pacifico AD, Bargeron LM Jr, Kirklin JW (1973) Primary total correction of tetralogy of Fallot in children less than four years of age. Circulation 48:1085–1091CrossRefPubMed
18.
go back to reference Pettersen MD, Du W, Skeens ME, Humes RA (2008) Regression equations for calculation of z-scores of cardiac structures in a large cohort of healthy infants, children, and adolescents: an echocardiographic study. J Am Soc Echocardiogr 21:922–934. doi:10.1016/j.echo.2008.02.006 S0894-7317(08)00119-3 [pii]CrossRefPubMed Pettersen MD, Du W, Skeens ME, Humes RA (2008) Regression equations for calculation of z-scores of cardiac structures in a large cohort of healthy infants, children, and adolescents: an echocardiographic study. J Am Soc Echocardiogr 21:922–934. doi:10.​1016/​j.​echo.​2008.​02.​006 S0894-7317(08)00119-3 [pii]CrossRefPubMed
19.
go back to reference Pigula FA, Khalil PN, Mayer JE, del Nido PJ, Jonas RA (1999) Repair of tetralogy of Fallot in neonates and young infants. Circulation 100(19 suppl):II157–II161PubMed Pigula FA, Khalil PN, Mayer JE, del Nido PJ, Jonas RA (1999) Repair of tetralogy of Fallot in neonates and young infants. Circulation 100(19 suppl):II157–II161PubMed
Metadata
Title
Stenting of the Right Ventricular Outflow Tract in the High-Risk Infant With Cyanotic Teratology of Fallot
Authors
Chesney D. Castleberry
Todd M. Gudausky
Stuart Berger
James S. Tweddell
Andrew N. Pelech
Publication date
01-03-2014
Publisher
Springer US
Published in
Pediatric Cardiology / Issue 3/2014
Print ISSN: 0172-0643
Electronic ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-013-0796-z

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