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Indian Journal of Hematology and Blood Transfusion
Published in: Indian Journal of Hematology and Blood Transfusion 1/2014

01-09-2014 | Case Report

Stem Cell Transplant for Juvenile Myelomonocytic Leukemia and Chronic Myelomonocytic Leukemia

Authors: Dharma Choudhary, Sanjeev Kumar Sharma, Nitin Gupta, Anil Handoo

Published in: Indian Journal of Hematology and Blood Transfusion | Special Issue 1/2014

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Abstract

Juvenile myelomonocytic leukemia (JMML) and chronic myelomonocytic leukemia (CMML) are myelodysplastic/myeloproliferative neoplasms associated with poor prognosis. There is no definitive treatment for such patients other than stem cell transplantation, and chemotherapy is not much effective. Timely diagnosis and early referral to the transplant centre is important for the management of these diseases. We report here a case of JMML and another case of CMML who were treated successfully with peripheral blood stem cell transplantation.
Literature
1.
Vardiman JW, Bennett JM, Bain BJ, Baumann I, Thiele J, Orazi A (2008) Myelodysplastic/myeloproliferative neoplasms, unclassifiable. In: Swerdlow S, Campo E, Harris NL (eds) International agency for research on cancer. WHO classification of tumours of haematopoietic and lymphoid tissue. World Health Organization, Geneva, Switzerland
2.
Emanuel PD (2008) Juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia: spotlight review. Leukemia 22:1335–1342PubMedCrossRef
3.
Arico M, Biondi A, Pui CH (1997) Juvenile myelomonocytic leukemia. Blood 90:479–488PubMed
4.
Niemeyer CM, Arico M, Basso G (1997) Chronic myelomonocytic leukemia in childhood: a retrospective analysis of 110 cases. Blood 89:3534–3543PubMed
5.
Locatelli F, Niemeyer CM, Angelucoi E (1997) Allogeneic bone marrow transplantation for chronic myelomonocytic leukaemia in childhood: a report from the European Working Group on Myelodysplastic Syndrome in Childhood. J Clin Oncol 15:566–573PubMed
6.
Festa RS, Shende A, Lanzkowsky P (1990) Juvenile chronic myelocytic leukemia: experience with intensive combination chemotherapy. Med Pediatr Oncol 18:311–316PubMedCrossRef
7.
Chan HSL, Estrov Z, Weitzmann SS, Freedman MH (1987) The value of intensive combination chemotherapy for juvenile chronic myelogenous leukemia. J Clin Oncol 5:1960–1967PubMed
8.
Sanders JE, Buckner CD, Stewart P, Thomas ED (1979) Successful treatment of juvenile chronic granulocytic leukemia with bone marrow transplantation. Pediatrics 63:44–46PubMed
9.
MacMillan ML, Davies SM, Orchard PJ et al (1998) Haemopoietic cell transplantation in children with juvenile myelomonocytic leukaemia. Br J Haematol 103:552–558PubMedCrossRef
10.
Locatelli F, Nöllke P, Zecca M et al (2005) Hematopoietic stem cell transplantation in children with juvenile myelomonocytic leukemia: results of the EWOG-MDS/EBMT trial. Blood 105:410–419PubMedCrossRef
11.
Parikh SA, Tefferi A (2012) Chronic myelomonocytic leukemia: 2012 update on diagnosis, risk stratification, and management. Am J Hematol 87:611–619CrossRef
12.
Eissa H, Gooley TA, Sorror ML (2011) Allogeneic hematopoietic cell transplantation for chronic myelomonocytic leukemia: relapse-free survival is determined by karyotype and comorbidities. Biol Blood Marrow Transpl 17:908–915CrossRef
Metadata
Title
Stem Cell Transplant for Juvenile Myelomonocytic Leukemia and Chronic Myelomonocytic Leukemia
Authors
Dharma Choudhary
Sanjeev Kumar Sharma
Nitin Gupta
Anil Handoo
Publication date
01-09-2014
Publisher
Springer India
Published in
Indian Journal of Hematology and Blood Transfusion / Issue Special Issue 1/2014
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI
https://doi.org/10.1007/s12288-013-0233-8

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