Published in:
01-03-2022 | Status Epilepticus | Original Article
New-onset status epilepticus in SARS-CoV-2 infection: a case series
Authors:
Marco Belluzzo, Annacarmen Nilo, Mariarosaria Valente, Gian Luigi Gigli
Published in:
Neurological Sciences
|
Issue 3/2022
Login to get access
Abstract
Background
Neurological manifestations of COVID-19 infection are well recognized. Seizures and status epilepticus (SE) have been reported as possible manifestations and/or complications of SARS-CoV-2 infection at different disease stages, but few data are known about the type, severity, treatment response, and recurrence.
Methods
Single-center retrospective case series.
Results
This case series describes four COVID-19-positive patients admitted to an Italian University Hospital, who developed status epilepticus during the active phase of disease, independently from the severity of respiratory symptoms. Two of them presented a relapse after resolution of the acute viral infection, a feature that has not been previously reported.
Conclusions
Although a possible association between SE and COVID-19 has been reported, the exact etiopathogenetic mechanism remains still not understood. Our series adds new insights to shed further light on this controversial issue.