Published in:
01-09-2010 | Nephrology - Editorial
Statin use in patients with chronic kidney disease stages 2–4: targeting beyond improved mortality rates
Authors:
Kosmas I. Paraskevas, Alexandros A. Tzovaras, Vassilios Stathopoulos, Dimitri P. Mikhailidis
Published in:
International Urology and Nephrology
|
Issue 3/2010
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Excerpt
The well-designed study by Neves et al. [
1] showed that statin and/or vitamin D non-use were independent risk factors of mortality (
p = 0.005) in their cohort of patients (
n = 95) with chronic kidney disease (CKD) stages 4 and 5 (mean estimated glomerular filtration rate [eGFR] = 16.1 ml/min/1.73 m
2). After a mean follow-up of 24.1 ± 9.8 months, all patients receiving both statins and vitamin D were alive (18 of 18 patients; 100%). In contrast, only 24 of the 43 patients (56.4%) receiving neither a statin nor vitamin D were alive at the end of the study [
1]. …