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01-02-2004 | Poster presentation

Sputum concentration of amikacin varies with nebulizer efficiency measured in vitro in patients on mechanical ventilators

Authors: P Dequin, E Mercier, C Valat, R Fishman, J Fink, N Smith, K Gibbons, P Diot

Published in: Critical Care | Special Issue 1/2004

Excerpt

Evaluation of the clinical utility of aerosolized antibiotics in patients with ventilator-associated pneumonia has been hampered by the inefficiency of available nebulizers. The Aerogen pulmonary drug delivery system (APD) is in development for high-efficiency lung deposition of novel therapies in mechanically ventilated patients. We compared delivery of amikacin (AMIK) via APD vs the the Aeroneb Pro (AP), and vs the AirLife™ Misty Neb™ (MN), in mechanically ventilated patients. We wanted to determine how AMIK concentrations in the sputum relate to device efficiency previously determined in vitro [1]. …

Fink JB, Uster P, Fishman R: In Vitro Evaluation of Aerosol Delivery of Amikacin During Mechanical Ventilation Baltimore, MD: International Society of Aerosol Medicine 2003.

Title: Sputum concentration of amikacin varies with nebulizer efficiency measured in vitro in patients on mechanical ventilators
Authors: P Dequin
E Mercier
C Valat
R Fishman
J Fink
N Smith
K Gibbons
P Diot
Publication date: 01-02-2004
Publisher: BioMed Central
Published in: Critical Care / Issue Special Issue 1/2004
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/cc2696

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Sputum concentration of amikacin varies with nebulizer efficiency measured in vitro in patients on mechanical ventilators

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

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