Issue 4/2021
Content (22 Articles)
How Will Aducanumab Approval Impact AD Research?
Michael W. Weiner, P. S. Aisen, L. A. Beckett, R. C. Green, W. Jagust, J. C. Morris, O. Okonkwo, R. J. Perrin, R. C. Petersen, M. Rivera Mindt, A. J. Saykin, L. M. Shaw, A. W. Toga, J. Q. Trojanowski
Consequences of the FDA Decision on Aducanumab for Patient Care and Research
Rachelle Doody
Impact of Aduhelm Approval on Care and Policy
B. Kallmyer, M. Daven, L. Thornhill, K. Clifford, R. Conant, Maria C. Carrillo
Aducanumab: Appropriate Use Recommendations
Jeffrey Cummings, P. Aisen, L. G. Apostolova, A. Atri, S. Salloway, M. Weiner
The US Expert Panel on the Appropriate Use Recommendations of Aducanumab in Clinical Practice
Serge Gauthier, P. Rosa-Neto
Donanemab (LY3002813) Phase 1b Study in Alzheimer’s Disease: Rapid and Sustained Reduction of Brain Amyloid Measured by Florbetapir F18 Imaging
S. L. Lowe, C. Duggan Evans, S. Shcherbinin, Y.-J. Cheng, B. A. Willis, I. Gueorguieva, A. C. Lo, A. S. Fleisher, J. L. Dage, P. Ardayfio, G. Aguiar, M. Ishibai, G. Takaichi, L. Chua, G. Mullins, John R. Sims
The Cost-Effectiveness of Three Prevention Strategies in Alzheimer’s Disease: Results from the Multidomain Alzheimer Preventive Trial (MAPT)
Nadège Costa, M. Mounié, A. Pagès, H. Derumeaux, T. Rapp, S. Guyonnet, N. Coley, C. Cantet, I. Carrié, S. Andrieu, L. Molinier
The Association between Peanut and Peanut Butter Consumption and Cognitive Function among Community-Dwelling Older Adults
Elizabeth W. Katzman, S. J. Nielsen
Early-Onset Subgroup of Type 2 Diabetes and Risk of Dementia, Alzheimer’s disease and Stroke: A Cohort Study
K. Wang, Hong Liu
A UK-Wide Study Employing Natural Language Processing to Determine What Matters to People about Brain Health to Improve Drug Development: The Electronic Person-Specific Outcome Measure (ePSOM) Programme
Stina Saunders, G. Muniz-Terrera, S. Sheehan, C. W. Ritchie, S. Luz
A Fay-Herriot Model for Estimating Subjective Cognitive Decline among Military Veterans
Justin T. McDaniel, R. J. McDermott, T. Schneider
Alzheimer’s Disease Research in Japan: A Short History, Current Status and Future Perspectives toward Prevention
Takeshi Iwatsubo, Y. Niimi, H. Akiyama
The Japan-Multimodal Intervention Trial for Prevention of Dementia (J-MINT): The Study Protocol for an 18-Month, Multicenter, Randomized, Controlled Trial
T. Sugimoto, Takashi Sakurai, H. Akatsu, T. Doi, Y. Fujiwara, A. Hirakawa, F. Kinoshita, M. Kuzuya, S. Lee, K. Matsuo, M. Michikawa, S. Ogawa, R. Otsuka, K. Sato, H. Shimada, H. Suzuki, H. Suzuki, H. Takechi, S. Takeda, H. Umegaki, S. Wakayama, H. Arai
Peripheral Blood BRCA1 Methylation Positively Correlates with Major Alzheimer’s Disease Risk Factors
Tatsuo Mano, K. Sato, T. Ikeuchi, T. Toda, T. Iwatsubo, A. Iwata
Tauroursodeoxycholic Acid Attenuates Diet-Induced and Age-Related Peripheral Endoplasmic Reticulum Stress and Cerebral Amyloid Pathology in a Mouse Model of Alzheimer’s Disease
T. Ochiai, T. Nagayama, K. Matsui, K. Amano, T. Sano, Tomoko Wakabayashi, Takeshi Iwatsubo
A Japanese Multicenter Study on PET and Other Biomarkers for Subjects with Potential Preclinical and Prodromal Alzheimer’s Disease
Michio Senda, K. Ishii, K. Ito, T. Ikeuchi, H. Matsuda, T. Iwatsubo, A. Iwata, R. Ihara, K. Suzuki, K. Kasuga, Y. Ikari, Y. Niimi, H. Arai, A. Tamaoka, Y. Arahata, Y. Itoh, H. Tachibana, Y. Ichimiya, S. Washizuka, T. Odawara, K. Ishii, K. Ono, T. Yokota, A. Nakanishi, E. Matsubara, H. Mori, H. Shimada
Cohort-Specific Optimization of Models Predicting Preclinical Alzheimer’s Disease, to Enhance Screening Performance in the Middle of Preclinical Alzheimer’s Disease Clinical Studies
K. Sato, T. Mano, R. Ihara, K. Suzuki, Y. Niimi, T. Toda, T. Iwatsubo, Atsushi Iwata
Using Digital Tools to Advance Alzheimer’s Drug Trials During a Pandemic: The EU/US CTAD Task Force
Jeffrey Kaye, P. Aisen, R. Amariglio, R. Au, C. Ballard, M. Carrillo, H. Fillit, T. Iwatsubo, G. Jimenez-Maggiora, S. Lovestone, F. Natanegara, K. Papp, M. E. Soto, M. Weiner, B. Vellas
Comparative Efficacy, Safety, Tolerability, and Effectiveness of Antipsychotics in The Treatment of Dementia-Related Psychosis (DRP): A Systematic Literature Review
I. Yunusa, N. Rashid, V. Abler, Krithika Rajagopalan
Immunotherapy for Alzheimer’s Disease: Current Scenario and Future Perspectives
M. B. Usman, S. Bhardwaj, S. Roychoudhury, D. Kumar, A. Alexiou, P. Kumar, R. K. Ambasta, P. Prasher, S. Shukla, V. Upadhye, F. A. Khan, R. Awasthi, M. D. Shastri, S. K. Singh, G. Gupta, D. K. Chellappan, K. Dua, S. K. Jha, J. Ruokolainen, K. K. Kesari, Shreesh Ojha, Niraj Kumar Jha
Childhood Secondhand Smoke Exposure and Risk of Dementia in Adulthood
Tomoyuki Kawada