Issue 8/2017
Content (22 Articles)
Up front
Beta cell heterogeneity: an evolving concept
Dana Avrahami, Agnes Klochendler, Yuval Dor, Benjamin Glaser
Metabolically inactive insulin: friend or foe in the prevention of autoimmune diabetes?
Mikael Knip
SGLT2 inhibitors and diabetic ketoacidosis: data from the FDA Adverse Event Reporting System
Gian Paolo Fadini, Benedetta Maria Bonora, Angelo Avogaro
Effects of semaglutide on beta cell function and glycaemic control in participants with type 2 diabetes: a randomised, double-blind, placebo-controlled trial
Christoph Kapitza, Kirsten Dahl, Jacob B. Jacobsen, Mads B. Axelsen, Anne Flint
Cardiovascular disease biomarkers are associated with declining renal function in type 2 diabetes
Sara J. Jenks, Bryan R. Conway, Stela McLachlan, Wei Leng Teoh, Rachel M. Williamson, David J. Webb, Paul Welsh, Naveed Sattar, Mark W. J. Strachan, Jackie F. Price
Association of serum microRNAs with islet autoimmunity, disease progression and metabolic impairment in relatives at risk of type 1 diabetes
Isaac V. Snowhite, Gloria Allende, Jay Sosenko, Ricardo L. Pastori, Shari Messinger Cayetano, Alberto Pugliese
In vivo measurement and biological characterisation of the diabetes-associated mutant insulin p.R46Q (GlnB22-insulin)
Julie Støy, Jørgen Olsen, Soo-Young Park, Søren Gregersen, Claudia U. Hjørringgaard, Graeme I. Bell
HSF1 acetylation decreases its transcriptional activity and enhances glucolipotoxicity-induced apoptosis in rat and human beta cells
Indri Purwana, Jun J. Liu, Bernard Portha, Jean Buteau
GLP-1 signalling compensates for impaired insulin signalling in regulating beta cell proliferation in βIRKO mice
Dan Kawamori, Jun Shirakawa, Chong Wee Liew, Jiang Hu, Tomoaki Morioka, Alokesh Duttaroy, Bryan Burkey, Rohit N. Kulkarni
Identification of a small molecule that facilitates the differentiation of human iPSCs/ESCs and mouse embryonic pancreatic explants into pancreatic endocrine cells
Yasushi Kondo, Taro Toyoda, Ryo Ito, Michinori Funato, Yoshiya Hosokawa, Satoshi Matsui, Tomomi Sudo, Masahiro Nakamura, Chihiro Okada, Xiaotong Zhuang, Akira Watanabe, Akira Ohta, Nobuya Inagaki, Kenji Osafune
Antibodies to post-translationally modified insulin as a novel biomarker for prediction of type 1 diabetes in children
Rocky Strollo, Chiara Vinci, Nicola Napoli, Paolo Pozzilli, Johnny Ludvigsson, Ahuva Nissim
Metabolically inactive insulin analogue does not prevent autoimmune diabetes in NOD mice
Juha Grönholm, Philippe P. Pagni, Minh N. Pham, Claire B. Gibson, Paul F. Macomber, José Luis Vela, Matthias von Herrath, Michael J. Lenardo
Glucose metabolism during rotational shift-work in healthcare workers
Anu Sharma, Marcello C. Laurenti, Chiara Dalla Man, Ron T. Varghese, Claudio Cobelli, Robert A. Rizza, Aleksey Matveyenko, Adrian Vella
Bed rest and resistive vibration exercise unveil novel links between skeletal muscle mitochondrial function and insulin resistance
Helena C. Kenny, Floriane Rudwill, Laura Breen, Michele Salanova, Dieter Blottner, Tim Heise, Martina Heer, Stephane Blanc, Donal J. O’Gorman
Impact of brown rice-specific γ-oryzanol on epigenetic modulation of dopamine D2 receptors in brain striatum in high-fat-diet-induced obesity in mice
Chisayo Kozuka, Tadashi Kaname, Chigusa Shimizu-Okabe, Chitoshi Takayama, Masato Tsutsui, Masayuki Matsushita, Keiko Abe, Hiroaki Masuzaki
Unravelling the regulation of insulin transport across the brain endothelial cell
Sarah M. Gray, Kevin W. Aylor, Eugene J. Barrett
The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation
Klaudia Kulak, Gunilla T. Westermark, Nikolina Papac-Milicevic, Erik Renström, Anna M. Blom, Ben C. King
Retinal oxygen extraction in individuals with type 1 diabetes with no or mild diabetic retinopathy
Klemens Fondi, Piotr A. Wozniak, Kinga Howorka, Ahmed M. Bata, Gerold C. Aschinger, Alina Popa-Cherecheanu, Katarzyna J. Witkowska, Anton Hommer, Doreen Schmidl, René M. Werkmeister, Gerhard Garhöfer, Leopold Schmetterer
Retinopathy with central oedema in an INS C94Y transgenic pig model of long-term diabetes
Kristina J. H. Kleinwort, Barbara Amann, Stefanie M. Hauck, Sieglinde Hirmer, Andreas Blutke, Simone Renner, Patrizia B. Uhl, Karina Lutterberg, Walter Sekundo, Eckhard Wolf, Cornelia A. Deeg
Metformin prevents ischaemic ventricular fibrillation in metabolically normal pigs
Li Lu, Shuyu Ye, Rebecca L. Scalzo, Jane E. B. Reusch, Clifford R. Greyson, Gregory G. Schwartz