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Diabetologia

Issue 11/2013

Content (27 Articles)

For Debate

Do post-translational beta cell protein modifications trigger type 1 diabetes?

Joachim Størling, Anne Julie Overgaard, Caroline Anna Brorsson, Francesco Piva, Claus Heiner Bang-Berthelsen, Claus Haase, Jørn Nerup, Flemming Pociot

Open Access Article

Effect of early intensive multifactorial therapy compared with routine care on self-reported health status, general well-being, diabetes-specific quality of life and treatment satisfaction in screen-detected type 2 diabetes mellitus patients (ADDITION-Europe): a cluster-randomised trial

Maureen Van den Donk, Simon J. Griffin, Rebecca K. Stellato, Rebecca K. Simmons, Annelli Sandbæk, Torsten Lauritzen, Kamlesh Khunti, Melanie J. Davies, Knut Borch-Johnsen, Nicholas J. Wareham, Guy E. H. M. Rutten

Short Communication

Does metformin modify the effect on glycaemic control of aerobic exercise, resistance exercise or both?

Normand G. Boulé, Glen P. Kenny, Joanie Larose, Farah Khandwala, Nicholas Kuzik, Ronald J. Sigal

Article

Glucocorticoid treatment impairs microvascular function in healthy men in association with its adverse effects on glucose metabolism and blood pressure: a randomised controlled trial

Daniël H. van Raalte, Michaela Diamant, D. Margriet Ouwens, Richard G. Ijzerman, Margot M. L. Linssen, Bruno Guigas, Etto C. Eringa, Erik H. Serné

Article

Long-term outcome of insulin pump therapy in children with type 1 diabetes assessed in a large population-based case–control study

Stephanie R. Johnson, Matthew N. Cooper, Timothy W. Jones, Elizabeth A. Davis

Short Communication

Time trends in mortality rates in type 1 diabetes from 2002 to 2011

Marit E. Jørgensen, Thomas P. Almdal, Bendix Carstensen

Article

Parental history of type 2 diabetes, TCF7L2 variant and lower insulin secretion are associated with incident hypertension. Data from the DESIR and RISC cohorts

Fabrice Bonnet, Ronan Roussel, Andrea Natali, Stéphane Cauchi, John Petrie, Martine Laville, Loïc Yengo, Philippe Froguel, Céline Lange, Olivier Lantieri, Michel Marre, Beverley Balkau, Ele Ferrannini

Article

Plasticity of Schwann cells and pericytes in response to islet injury in mice

Shiue-Cheng Tang, Yu-Chen Chiu, Chia-Tung Hsu, Shih-Jung Peng, Ya-Yuan Fu

Article

Downregulation of Sfrp5 promotes beta cell proliferation during obesity in the rat

Sandra A. Rebuffat, Joana M. Oliveira, Jordi Altirriba, Nuria Palau, Ainhoa Garcia, Yaiza Esteban, Belen Nadal, Ramon Gomis

Article

Exendin-4 protects pancreatic beta cells from palmitate-induced apoptosis by interfering with GPR40 and the MKK4/7 stress kinase signalling pathway

Annalisa Natalicchio, Rossella Labarbuta, Federica Tortosa, Giuseppina Biondi, Nicola Marrano, Alessandro Peschechera, Emanuele Carchia, Maura Roberta Orlando, Anna Leonardini, Angelo Cignarelli, Piero Marchetti, Sebastio Perrini, Luigi Laviola, Francesco Giorgino

Article

The novel chemokine receptor, G-protein-coupled receptor 75, is expressed by islets and is coupled to stimulation of insulin secretion and improved glucose homeostasis

Bo Liu, Zoheb Hassan, Stefan Amisten, Aileen J. King, James E. Bowe, Guo Cai Huang, Peter M. Jones, Shanta J. Persaud

Article

Nupr1 deletion protects against glucose intolerance by increasing beta cell mass

Helena C. Barbosa-Sampaio, Bo Liu, Robert Drynda, Ana M. Rodriguez de Ledesma, Aileen J. King, James E. Bowe, Cédric Malicet, Juan L. Iovanna, Peter M. Jones, Shanta J. Persaud, Dany S. Muller

Article

Obesity phenotype is related to NLRP3 inflammasome activity and immunological profile of visceral adipose tissue

Nathalie Esser, Laurent L’homme, Arnaud De Roover, Laurent Kohnen, André J. Scheen, Michel Moutschen, Jacques Piette, Sylvie Legrand-Poels, Nicolas Paquot

Open Access Article

Analysis of naturally occurring mutations in the human lipodystrophy protein seipin reveals multiple potential pathogenic mechanisms

M. F. Michelle Sim, M. Mesbah Uddin Talukder, Rowena J. Dennis, Stephen O’Rahilly, J. Michael Edwardson, Justin J. Rochford

Article

A role for adipocyte-derived lipopolysaccharide-binding protein in inflammation- and obesity-associated adipose tissue dysfunction

José María Moreno-Navarrete, Xavier Escoté, Francisco Ortega, Matteo Serino, Mark Campbell, Marie-Caroline Michalski, Martine Laville, Gemma Xifra, Elodie Luche, Pere Domingo, Mónica Sabater, Gerard Pardo, Aurelie Waget, Javier Salvador, Marta Giralt, Jose I. Rodriguez-Hermosa, Marta Camps, Catherine I. Kolditz, Nathalie Viguerie, Jean Galitzky, Pauline Decaunes, Wifredo Ricart, Gema Frühbeck, Francesc Villarroya, Geltrude Mingrone, Dominique Langin, Antonio Zorzano, Hubert Vidal, Joan Vendrell, Remy Burcelin, Antonio Vidal-Puig, José Manuel Fernández-Real

Research Letter

High frequency of autoantibodies in patients with long duration type 1 diabetes

Carolyn C. Richardson, James A. Dromey, Kerry A. McLaughlin, Diana Morgan, H. Jonathan Bodansky, Richard G. Feltbower, Anthony H. Barnett, Geoffrey V. Gill, Steven C. Bain, Michael R. Christie

Letter

The diagnosis of insulitis in human type 1 diabetes

M. L. Campbell-Thompson, M. A. Atkinson, A. E. Butler, N. M. Chapman, G. Frisk, R. Gianani, B. N. Giepmans, M. G. von Herrath, H. Hyöty, T. W. Kay, O. Korsgren, N. G. Morgan, A. C. Powers, A. Pugliese, S. J. Richardson, P. A. Rowe, S. Tracy, P. A. In’t Veld

Erratum

Erratum to: HbA1c variability and the development of microalbuminuria in type 2 diabetes: Tsukuba Kawai Diabetes Registry 2

A. Sugawara, K. Kawai, S. Motohashi, K. Saito, S. Kodama, Y. Yachi, R. Hirasawa, H. Shimano, K. Yamazaki, H. Sone

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.