Skip to main content
Top

Diabetologia

Issue 10/2012

Content (42 Articles)

Open Access Commentary

Targeting adipose tissue angiogenesis to enhance insulin sensitivity

L. Mannerås-Holm, A. Krook

Review

Lymphocytes in obesity-related adipose tissue inflammation

A. Chatzigeorgiou, K. P. Karalis, S. R. Bornstein, T. Chavakis

Article

Cancer outcomes and all-cause mortality in adults allocated to metformin: systematic review and collaborative meta-analysis of randomised clinical trials

R. J. Stevens, R. Ali, C. R. Bankhead, M. A. Bethel, B. J. Cairns, R. P. Camisasca, F. L. Crowe, A. J. Farmer, S. Harrison, J. A. Hirst, P. Home, S. E. Kahn, J. H. McLellan, R. Perera, A. Plüddemann, A. Ramachandran, N. W. Roberts, P. W. Rose, A. Schweizer, G. Viberti, R. R. Holman

Article

A genotype risk score predicts type 2 diabetes from young adulthood: the CARDIA study

J. L. Vassy, N. H. Durant, E. K. Kabagambe, M. R. Carnethon, L. J. Rasmussen-Torvik, M. Fornage, C. E. Lewis, D. S. Siscovick, J. B. Meigs

Open Access Article

Body iron stores and risk of type 2 diabetes: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study

J. Montonen, H. Boeing, A. Steffen, R. Lehmann, A. Fritsche, H.-G. Joost, M. B. Schulze, T. Pischon

Article

The ratio of visceral to subcutaneous fat, a metric of body fat distribution, is a unique correlate of cardiometabolic risk

B. M. Kaess, A. Pedley, J. M. Massaro, J. Murabito, U. Hoffmann, C. S. Fox

Open Access Short Communication

Prevalence of monogenic diabetes amongst Polish children after a nationwide genetic screening campaign

W. Fendler, M. Borowiec, A. Baranowska-Jazwiecka, A. Szadkowska, E. Skala-Zamorowska, G. Deja, P. Jarosz-Chobot, I. Techmanska, J. Bautembach-Minkowska, M. Mysliwiec, A. Zmyslowska, I. Pietrzak, M. T. Malecki, W. Mlynarski

Open Access Article

Impact of FTO genotypes on BMI and weight in polycystic ovary syndrome: a systematic review and meta-analysis

P. Wojciechowski, A. Lipowska, P. Rys, K. G. Ewens, S. Franks, S. Tan, E. Lerchbaum, J. Vcelak, R. Attaoua, M. Straczkowski, R. Azziz, T. M. Barber, A. Hinney, B. Obermayer-Pietsch, P. Lukasova, B. Bendlova, F. Grigorescu, I. Kowalska, M. O. Goodarzi, J. F. Strauss III, M. I. McCarthy, M. T. Malecki

Open Access Article

Role of TCF7L2 risk variant and dietary fibre intake on incident type 2 diabetes

G. Hindy, E. Sonestedt, U. Ericson, X.-J. Jing, Y. Zhou, O. Hansson, E. Renström, E. Wirfält, M. Orho-Melander

Short Communication

Association between KCNQ1 genetic variants and obesity in Chinese patients with type 2 diabetes

W. Yu, R. C. Ma, C. Hu, W. Y. So, R. Zhang, C. Wang, C. H. Tam, J. S. Ho, J. Lu, F. Jiang, S. Tang, M. C. Ng, Y. Bao, K. Xiang, W. Jia, J. C. N. Chan

Article

Common polymorphism near the MC4R gene is associated with type 2 diabetes: data from a meta-analysis of 123,373 individuals

B. Xi, F. Takeuchi, G. R. Chandak, N. Kato, H. W. Pan, D. H. Zhou, H. Y. Pan, J. Mi

Article

Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice

G. da Silva Xavier, A. Mondragon, G. Sun, L. Chen, J. A. McGinty, P. M. French, G. A. Rutter

Article

TCF7L2 rs7903146 impairs islet function and morphology in non-diabetic individuals

O. Le Bacquer, J. Kerr-Conte, S. Gargani, N. Delalleau, M. Huyvaert, V. Gmyr, P. Froguel, B. Neve, F. Pattou

Article

G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1

M. Ferdaoussi, V. Bergeron, B. Zarrouki, J. Kolic, J. Cantley, J. Fielitz, E. N. Olson, M. Prentki, T. Biden, P. E. MacDonald, V. Poitout

Article

Postprandial VLDL-triacylglycerol secretion is not suppressed in obese type 2 diabetic men

E. Søndergaard, L. P. Sørensen, I. Rahbek, L. C. Gormsen, J. S. Christiansen, S. Nielsen

Short Communication

Regulation of plasma ceramide levels with fatty acid oversupply: evidence that the liver detects and secretes de novo synthesised ceramide

M. J. Watt, A. C. Barnett, C. R. Bruce, S. Schenk, J. F. Horowitz, A. J. Hoy

Article

Beneficial effects of the novel cholecystokinin agonist (pGlu-Gln)-CCK-8 in mouse models of obesity/diabetes

N. Irwin, P. Frizelle, I. A. Montgomery, R. C. Moffett, F. P. M. O’Harte, P. R. Flatt

Article

Targeting of mitochondrial reactive oxygen species production does not avert lipid-induced insulin resistance in muscle tissue from mice

S. Paglialunga, B. van Bree, M. Bosma, M. P. Valdecantos, E. Amengual-Cladera, J. A. Jörgensen, D. van Beurden, G. J. M. den Hartog, D. M. Ouwens, J. J. Briedé, P. Schrauwen, J. Hoeks

Article

Skeletal muscle-specific overproduction of constitutively activated c-Jun N-terminal kinase (JNK) induces insulin resistance in mice

D. C. Henstridge, C. R. Bruce, C. P. Pang, G. I. Lancaster, T. L. Allen, E. Estevez, T. Gardner, J. M. Weir, P. J. Meikle, K. S. L. Lam, A. Xu, N. Fujii, L. J. Goodyear, M. A. Febbraio

Article

The glucose-lowering effects of the PDE4 inhibitors roflumilast and roflumilast-N-oxide in db/db mice

S. Vollert, N. Kaessner, A. Heuser, G. Hanauer, A. Dieckmann, D. Knaack, H. P. Kley, R. Beume, C. Weiss-Haljiti

Short Communication

Deletion of protein kinase Cε in mice has limited effects on liver metabolite levels but alters fasting ketogenesis and gluconeogenesis

K. Raddatz, G. Frangioudakis, B. Diakanastasis, B. M. Liao, M. Leitges, C. Schmitz-Peiffer

Short Communication

Effect of rosiglitazone on capillary density and angiogenesis in adipose tissue of normoglycaemic humans in a randomised controlled trial

O. Gealekman, N. Guseva, K. Gurav, A. Gusev, C. Hartigan, M. Thompson, S. Malkani, S. Corvera

Article

Systemic inflammation in childhood obesity: circulating inflammatory mediators and activated CD14++ monocytes

H. S. Schipper, R. Nuboer, S. Prop, H. J. van den Ham, F. K. de Boer, Ç. Kesmir, I. M. H. Mombers, K. A. van Bekkum, J. Woudstra, J. H. Kieft, I. E. Hoefer, W. de Jager, B. Prakken, M. van Summeren, E. Kalkhoven

Open Access Article

Adipocyte-released insulin-like growth factor-1 is regulated by glucose and fatty acids and controls breast cancer cell growth in vitro

V. D’Esposito, F. Passaretti, A. Hammarstedt, D. Liguoro, D. Terracciano, G. Molea, L. Canta, C. Miele, U. Smith, F. Beguinot, P. Formisano

Article

Modulation of gut microbiota by antibiotics improves insulin signalling in high-fat fed mice

B. M. Carvalho, D. Guadagnini, D. M. L. Tsukumo, A. A. Schenka, P. Latuf-Filho, J. Vassallo, J. C. Dias, L. T. Kubota, J. B. C. Carvalheira, M. J. A. Saad

Article

Reduction of experimental diabetic vascular leakage and pericyte apoptosis in mice by delivery of αA-crystallin with a recombinant adenovirus

Y. H. Kim, S. Y. Park, J. Park, Y. S. Kim, E. M. Hwang, J. Y. Park, G. S. Roh, H. J. Kim, S. S. Kang, G. J. Cho, W. S. Choi

Research Letter

GATA6 inactivating mutations are associated with heart defects and, inconsistently, with pancreatic agenesis and diabetes

A. Bonnefond, O. Sand, B. Guerin, E. Durand, F. De Graeve, M. Huyvaert, L. Rachdi, J. Kerr-Conte, F. Pattou, M. Vaxillaire, M. Polak, R. Scharfmann, P. Czernichow, P. Froguel

Letter

A critique of the 2012 ADA/EASD position statement

H. W. Rodbard, P. S. Jellinger

Erratum

Erratum to: Impact of FTO genotypes on BMI and weight in polycystic ovary syndrome: a systematic review and meta-analysis

P. Wojciechowski, A. Lipowska, P. Rys, K. G. Ewens, S. Franks, S. Tan, E. Lerchbaum, J. Vcelak, R. Attaoua, M. Straczkowski, R. Azziz, T. M. Barber, A. Hinney, B. Obermayer-Pietsch, P. Lukasova, B. Bendlova, F. Grigorescu, I. Kowalska, M. O. Goodarzi, J. F. Strauss III, M. I. McCarthy, M. T. Malecki

Erratum

Erratum to: Relationship between HbA1c levels and risk of cardiovascular adverse outcomes and all-cause mortality in overweight and obese cardiovascular high-risk women and men with type 2 diabetes

C. Andersson, L. van Gaal, I. D. Caterson, P. Weeke, W. P. T. James, W. Coutinho, N. Finer, A. M. Sharma, A. P. Maggioni, C. Torp-Pedersen

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.