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Diabetologia

Issue 1/2018

Content (30 Articles)

Up Front

Up Front

Open Access In memoriam

Gian Franco Bottazzo, 1946–2017

Ezio Bonifacio, Emanuele Bosi, R. David Leslie

Open Access Review

Epigenetics in diabetic nephropathy, immunity and metabolism

Samuel T. Keating, Janna A. van Diepen, Niels P. Riksen, Assam El-Osta

Review

Diabetic cardiomyopathy: a hyperglycaemia- and insulin-resistance-induced heart disease

Guanghong Jia, Adam Whaley-Connell, James R. Sowers

Commentary

When beta cells talk back

Heather C. Denroche, Dominika Nackiewicz, C. Bruce Verchere

Open Access Article

Day-to-day fasting glycaemic variability in DEVOTE: associations with severe hypoglycaemia and cardiovascular outcomes (DEVOTE 2)

Bernard Zinman, Steven P. Marso, Neil R. Poulter, Scott S. Emerson, Thomas R. Pieber, Richard E. Pratley, Martin Lange, Kirstine Brown-Frandsen, Alan Moses, Ann Marie Ocampo Francisco, Jesper Barner Lekdorf, Kajsa Kvist, John B. Buse

Open Access Article

DEVOTE 3: temporal relationships between severe hypoglycaemia, cardiovascular outcomes and mortality

Thomas R. Pieber, Steven P. Marso, Darren K. McGuire, Bernard Zinman, Neil R. Poulter, Scott S. Emerson, Richard E. Pratley, Vincent Woo, Simon Heller, Martin Lange, Kirstine Brown-Frandsen, Alan Moses, Jesper Barner Lekdorf, Lucine Lehmann, Kajsa Kvist, John B. Buse

Open Access Article

Random non-fasting C-peptide testing can identify patients with insulin-treated type 2 diabetes at high risk of hypoglycaemia

Suzy V. Hope, Bridget A. Knight, Beverley M. Shields, Anita V. Hill, Pratik Choudhary, W. David Strain, Timothy J. McDonald, Angus G. Jones

Open Access Article

Workplace bullying and violence as risk factors for type 2 diabetes: a multicohort study and meta-analysis

Tianwei Xu, Linda L. Magnusson Hanson, Theis Lange, Liis Starkopf, Hugo Westerlund, Ida E. H. Madsen, Reiner Rugulies, Jaana Pentti, Sari Stenholm, Jussi Vahtera, Åse M. Hansen, Mika Kivimäki, Naja H. Rod

Article

The shape of the glucose concentration curve during an oral glucose tolerance test predicts risk for type 1 diabetes

Heba M. Ismail, Ping Xu, Ingrid M. Libman, Dorothy J. Becker, Jennifer B. Marks, Jay S. Skyler, Jerry P. Palmer, Jay M. Sosenko

Open Access Article

Size and shape of the associations of glucose, HbA1c, insulin and HOMA-IR with incident type 2 diabetes: the Hoorn Study

Carolien Ruijgrok, Jacqueline M. Dekker, Joline W. Beulens, Ingeborg A. Brouwer, Veerle M. H. Coupé, Martijn W. Heymans, Femke P. C. Sijtsma, David J. Mela, Peter L. Zock, Margreet R. Olthof, Marjan Alssema

Short Communication

Glucose patterns during an oral glucose tolerance test and associations with future diabetes, cardiovascular disease and all-cause mortality rate

Adam Hulman, Dorte Vistisen, Charlotte Glümer, Michael Bergman, Daniel R. Witte, Kristine Færch

Open Access Article

Type 2 diabetes, socioeconomic status and life expectancy in Scotland (2012–2014): a population-based observational study

Jeremy Walker, Helen Colhoun, Shona Livingstone, Rory McCrimmon, John Petrie, Naveed Sattar, Sarah Wild

Open Access Article

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study

Sophie Molnos, Simone Wahl, Mark Haid, E. Marelise W. Eekhoff, René Pool, Anna Floegel, Joris Deelen, Daniela Much, Cornelia Prehn, Michaela Breier, Harmen H. Draisma, Nienke van Leeuwen, Annemarie M. C. Simonis-Bik, Anna Jonsson, Gonneke Willemsen, Wolfgang Bernigau, Rui Wang-Sattler, Karsten Suhre, Annette Peters, Barbara Thorand, Christian Herder, Wolfgang Rathmann, Michael Roden, Christian Gieger, Mark H. H. Kramer, Diana van Heemst, Helle K. Pedersen, Valborg Gudmundsdottir, Matthias B. Schulze, Tobias Pischon, Eco J. C. de Geus, Heiner Boeing, Dorret I. Boomsma, Anette G. Ziegler, P. Eline Slagboom, Sandra Hummel, Marian Beekman, Harald Grallert, Søren Brunak, Mark I. McCarthy, Ramneek Gupta, Ewan R. Pearson, Jerzy Adamski, Leen M. ’t Hart

Open Access Article

HbA1c is associated with altered expression in blood of cell cycle- and immune response-related genes

Roderick C. Slieker, Amber A. W. A. van der Heijden, Nienke van Leeuwen, Hailiang Mei, Giel Nijpels, Joline W. J. Beulens, Leen M. ’t Hart

Open Access Article

The chromosome 6q22.33 region is associated with age at diagnosis of type 1 diabetes and disease risk in those diagnosed under 5 years of age

Jamie R. J. Inshaw, Neil M. Walker, Chris Wallace, Leonardo Bottolo, John A. Todd

Article

Pancreatic neuro-insular network in young mice revealed by 3D panoramic histology

Shiue-Cheng Tang, Chia-Ning Shen, Pei-Yu Lin, Shih-Jung Peng, Hung-Jen Chien, Ya-Hsien Chou, Chester E. Chamberlain, Pankaj J. Pasricha

Article

Human pancreatic neuro-insular network in health and fatty infiltration

Shiue-Cheng Tang, Luc Baeyens, Chia-Ning Shen, Shih-Jung Peng, Hung-Jen Chien, David W. Scheel, Chester E. Chamberlain, Michael S. German

Article

Mouse pancreatic islet macrophages use locally released ATP to monitor beta cell activity

Jonathan R. Weitz, Madina Makhmutova, Joana Almaça, Julia Stertmann, Kristie Aamodt, Marcela Brissova, Stephan Speier, Rayner Rodriguez-Diaz, Alejandro Caicedo

Open Access Article

Pandemrix® vaccination is not associated with increased risk of islet autoimmunity or type 1 diabetes in the TEDDY study children

Helena Elding Larsson, Kristian F. Lynch, Maria Lönnrot, Michael J. Haller, Åke Lernmark, William A. Hagopian, Jin-Xiong She, Olli Simell, Jorma Toppari, Anette-G. Ziegler, Beena Akolkar, Jeffrey P. Krischer, Marian J. Rewers, Heikki Hyöty

Article

Live attenuated enterovirus vaccine (OPV) is not associated with islet autoimmunity in children with genetic susceptibility to type 1 diabetes: prospective cohort study

Hanna Viskari, Sami Oikarinen, Sanna Hoppu, Tytti Vuorinen, Heini Huhtala, Jorma Toppari, Riitta Veijola, Jorma Ilonen, Mikael Knip, Heikki Hyöty

Article

Differential effects of age and sex on insulin sensitivity and body composition in adolescent offspring of women with type 1 diabetes: results from the EPICOM study

Zuzana Lohse, Sine Knorr, Birgitte Bytoft, Tine D. Clausen, Rikke B. Jensen, Peter Oturai, Henning Beck-Nielsen, Claus H. Gravholt, Peter Damm, Kurt Højlund, Dorte M. Jensen

Article

Pioglitazone reduces cold-induced brown fat glucose uptake despite induction of browning in cultured human adipocytes: a randomised, controlled trial in humans

Rebecca K. C. Loh, Melissa F. Formosa, Nina Eikelis, David A. Bertovic, Mitchell J. Anderson, Shane A. Barwood, Shane Nanayakkara, Neale D. Cohen, Andre La Gerche, Anne T. Reutens, Kenneth S. Yap, Thomas W. Barber, Gavin W. Lambert, Martin H. Cherk, Stephen J. Duffy, Bronwyn A. Kingwell, Andrew L. Carey

Open Access Article

Biomarkers of inflammation and endothelial dysfunction as predictors of pulse pressure and incident hypertension in type 1 diabetes: a 20 year life-course study in an inception cohort

Isabel Ferreira, Peter Hovind, Casper G. Schalkwijk, Hans-Henrik Parving, Coen D. A. Stehouwer, Peter Rossing

Open Access Article

Association of maternal exposures with adiposity at age 4/5 years in white British and Pakistani children: findings from the Born in Bradford study

Jane West, Gillian Santorelli, Peter H. Whincup, Lesley Smith, Naveed A. Sattar, Noel Cameron, Diane Farrar, Paul Collings, John Wright, Debbie A. Lawlor

Retraction Note

Retraction Note to: L-glutamine supplementation induces insulin resistance in adipose tissue and improves insulin signalling in liver and muscle of rats with diet-induced obesity

P. O. Prada, S. M. Hirabara, C. T. de Souza, A. A. Schenka, H. G. Zecchin, J. Vassallo, L. A. Velloso, E. Carneiro, J. B. C. Carvalheira, R. Curi, M. J. Saad

Correction

Correction to: Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study

Maria Lönnrot, Kristian F. Lynch, Helena Elding Larsson, Åke Lernmark, Marian J. Rewers, Carina Törn, Brant R. Burkhardt, Thomas Briese, William A. Hagopian, Jin-Xiong She, Olli G. Simell, Jorma Toppari, Anette-G. Ziegler, Beena Akolkar, Jeffrey P. Krischer, Heikki Hyöty

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.