Issue 4/2013
Content (24 Articles)
New fronts in the adjuvant treatment of GIST
Peter Reichardt, Heikki Joensuu, Jean-Yves Blay
Receptor tyrosine kinase alterations and therapeutic opportunities in squamous cell carcinoma of the lung
Dong Wang, Licheng Du, Qi Liu, Xiangyan Liu, Zhou Wang
Bevacizumab confers additional advantage to the combination of trastuzumab plus pertuzumab in trastuzumab-refractory breast cancer model
Yuliang Sun, Nandini Dey, Melissa Brammer, Pradip De, Brian Leyland-Jones
A clinical investigation of inhibitory effect of panobinostat on CYP2D6 substrate in patients with advanced cancer
Ronald Feld, Margaret M. Woo, Natasha Leighl, Frances A. Shepherd, J. Thaddeus Beck, Lihui Zhao, Lucien Gazi, Thomas Hengelage, Maria Grazia Porro, Asha Nayak
Disruption of ZO-1/claudin-4 interaction in relation to inflammatory responses in methotrexate-induced intestinal mucositis
Kazuma Hamada, Naoko Kakigawa, Shuichi Sekine, Yoshihisa Shitara, Toshiharu Horie
Effects of pemetrexed, gefitinib, and their combination on human colorectal cancer cells
Guanzhong Zhang, Xiaodong Xie, Tianyi Liu, Jihua Yang, Shunchang Jiao
Lidamycin up-regulates the expression of thymidine phosphorylase and enhances the effects of capecitabine on the growth and pulmonary metastases of murine breast carcinoma
Sheng-hua Zhang, Hao Zhang, Hong-wei He, Liang Li, Xing-qi Li, Yi-ping Zhang, Rong-guang Shao
Inhibition of sorcin reverses multidrug resistance of K562/A02 cells and MCF-7/A02 cells via regulating apoptosis-related proteins
Yunhui Hu, Xin Cheng, Shuangjing Li, Yuan Zhou, Jianxiang Wang, Tao Cheng, Ming Yang, Dongsheng Xiong
Identification of two novel inhibitors of mTOR signaling pathway based on high content screening
Juming Yan, Hongyu Zhou, Lingmei Kong, Jing Zhang, Qinshi Zhao, Yan Li
A multicenter phase II study of belotecan, a new camptothecin analogue, in elderly patients with previously untreated, extensive-stage small cell lung cancer
Chang Dong Yeo, Sang Haak Lee, Ju Sang Kim, Seung Joon Kim, Seok Chan Kim, Young Kyoon Kim, Hyeon Hui Kang, Hyung Kyu Yoon, Jeong Sup Song, Hwa Sik Moon, Jin Woo Kim, Kwan Hyoung Kim, Byoung Yong Shim, Chi Hong Kim
A phase II study of neoadjuvant docetaxel, oxaliplatin, and S-1 (DOS) chemotherapy followed by surgery and adjuvant S-1 chemotherapy in potentially resectable gastric or gastroesophageal junction adenocarcinoma
Inkeun Park, Min-Hee Ryu, Yoon Hee Choi, Hyo Jeong Kang, Jeong Hwan Yook, Young Soo Park, Hyun Jin Kim, Hwoon-Yong Jung, Gin Hyug Lee, Kab Choong Kim, Byung Sik Kim, Yoon-Koo Kang
Pharmacogenetic determinants associated with sunitinib-induced toxicity and ethnic difference in Korean metastatic renal cell carcinoma patients
Hye Ryun Kim, Hyung Soon Park, Woo Sun Kwon, Ji Hyun Lee, Yusuke Tanigawara, Sun Min Lim, Hyo Song Kim, Sang Jun Shin, Jung Bae Ahn, Sun Young Rha
Treatment results and prognostic factors for advanced squamous cell carcinoma of the larynx treated with concurrent chemoradiotherapy
Takahide Taguchi, Goshi Nishimura, Masahiro Takahashi, Masanori Komatsu, Daisuke Sano, Naoko Sakuma, Yasuhiro Arai, Yukiko Yamashita, Osamu Shiono, Mariko Hirama, Yasunori Sakuma, Jun-ichi Ishitoya, Masaharu Hata, Ichiro Ogino, Nobuhiko Oridate
Phase II trial of gemcitabine and S-1 for patients with advanced pancreatic cancer
Hunho Song, Boram Han, Choong Kee Park, Jong Hyeok Kim, Jang Yong Jeon, In-Gyu Kim, Hyo Jung Kim, Joo Young Jung, Jung Han Kim, Jung Hye Kwon, Geundoo Jang, Ho Young Kim, Hyeong Su Kim, Dae Ro Choi, Dae Young Zang
Efficacy and safety of everolimus in Korean patients with metastatic renal cell carcinoma
Ki Hyang Kim, Sang Hyun Yoon, Hae-Jung Lee, Hyo Song Kim, Sang Joon Shin, Joong Bae Ahn, Sun Young Rha
A phase I/II study of carfilzomib 2–10-min infusion in patients with advanced solid tumors
Kyriakos P. Papadopoulos, Howard A. Burris III, Michael Gordon, Peter Lee, Edward A. Sausville, Peter J. Rosen, Amita Patnaik, Richard E. Cutler Jr., Zhengping Wang, Susan Lee, Suzanne F. Jones, Jeffery R. Infante
Reversibility of regorafenib effects in hepatocellular carcinoma cells
Rosalba D’Alessandro, Maria G. Refolo, Catia Lippolis, Caterina Messa, Aldo Cavallini, Roberta Rossi, Leonardo Resta, Antonio Di Carlo, Brian I. Carr
Pharmacokinetics and antineoplastic activity of galectin-1-targeting OTX008 in combination with sunitinib
Massimo Zucchetti, Katiuscia Bonezzi, Roberta Frapolli, Federica Sala, Patrizia Borsotti, Monique Zangarini, Esteban Cvitkovic, Kay Noel, Paolo Ubezio, Raffaella Giavazzi, Maurizio D’Incalci, Giulia Taraboletti
Clinical evaluation of targeted arterial perfusion of verapamil and chemotherapeutic drugs in interventional therapy of advanced lung cancer
Jin Huang, Tengyue Zhang, Kelong Ma, Pingsheng Fan, Yabei Liu, Chengtao Weng, Gaofei Fan, Qiaohong Duan, Xianhai Zhu
Clinical and laboratory studies of the novel cyclin-dependent kinase inhibitor dinaciclib (SCH 727965) in acute leukemias
Ivana Gojo, Mariola Sadowska, Alison Walker, Eric J. Feldman, Swaminathan Padmanabhan Iyer, Maria R. Baer, Edward A. Sausville, Rena G. Lapidus, Da Zhang, Yali Zhu, Ying-Ming Jou, Jennifer Poon, Karen Small, Rajat Bannerji
Tolerability, safety and pharmacokinetics of ridaforolimus in combination with bicalutamide in patients with asymptomatic, metastatic castration-resistant prostate cancer (CRPC)
Hielke J. Meulenbeld, Johann S. de Bono, Scott T. Tagawa, Young E. Whang, Xiaoyun Li, Karl H. Heath, Anthe S. Zandvliet, Scot W. Ebbinghaus, Gary R. Hudes, Ronald de Wit
Pharmacogenetically driven patient selection for a first-in-human phase I trial of batracylin in patients with advanced solid tumors and lymphomas
Shivaani Kummar, Martin E. Gutierrez, Lawrence W. Anderson, Raymond W. Klecker Jr., Alice Chen, Anthony J. Murgo, James H. Doroshow, Jerry M. Collins
Antitumor efficacy, toxicity and pharmacokinetics of 9-nitrocamptothecin: role of lactone ratio
Jun Chen, Rong-Rong Hu, Xi-Xiong Yang, Wei Gu, Rong Tian, Fang Gong, Lei Luo, Fang Fang, Zhi-Peng Chen, Bao-Chang Cai
Phase II study of docetaxel and vinorelbine as adjuvant chemotherapy for resected non-small cell lung cancers
Jamie E. Chaft, Natasha Rekhtman, Camelia S. Sima, Valerie Rusch, Mark G. Kris, Maureen Zakowski, Christopher G. Azzoli