Issue 6/2013
Content (12 Articles)
Protein aggregation in amyotrophic lateral sclerosis
Anna M. Blokhuis, Ewout J. N. Groen, Max Koppers, Leonard H. van den Berg, R. Jeroen Pasterkamp
Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson’s disease
Jens Wagner, Sergey Ryazanov, Andrei Leonov, Johannes Levin, Song Shi, Felix Schmidt, Catharina Prix, Francisco Pan-Montojo, Uwe Bertsch, Gerda Mitteregger-Kretzschmar, Markus Geissen, Martin Eiden, Fabienne Leidel, Thomas Hirschberger, Andreas A. Deeg, Julian J. Krauth, Wolfgang Zinth, Paul Tavan, Jens Pilger, Markus Zweckstetter, Tobias Frank, Mathias Bähr, Jochen H. Weishaupt, Manfred Uhr, Henning Urlaub, Ulrike Teichmann, Matthias Samwer, Kai Bötzel, Martin Groschup, Hans Kretzschmar, Christian Griesinger, Armin Giese
Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica
Tatsuro Misu, Romana Höftberger, Kazuo Fujihara, Isabella Wimmer, Yoshiki Takai, Shuhei Nishiyama, Ichiro Nakashima, Hidehiko Konno, Monika Bradl, Ferenc Garzuly, Yasuto Itoyama, Masashi Aoki, Hans Lassmann
C1q-targeted monoclonal antibody prevents complement-dependent cytotoxicity and neuropathology in in vitro and mouse models of neuromyelitis optica
Puay-Wah Phuan, Hua Zhang, Nithi Asavapanumas, Michael Leviten, Arnon Rosenthal, Lukmanee Tradtrantip, A. S. Verkman
Insufficient OPC migration into demyelinated lesions is a cause of poor remyelination in MS and mouse models
Amanda Boyd, Hui Zhang, Anna Williams
Clathrin adaptor CALM/PICALM is associated with neurofibrillary tangles and is cleaved in Alzheimer’s brains
Kunie Ando, Jean-Pierre Brion, Virginie Stygelbout, Valérie Suain, Michèle Authelet, Robert Dedecker, Anaïs Chanut, Pascale Lacor, Jérémie Lavaur, Véronique Sazdovitch, Ekaterina Rogaeva, Marie-Claude Potier, Charles Duyckaerts
Lingo-1 expression is increased in essential tremor cerebellum and is present in the basket cell pinceau
Sheng-Han Kuo, Guomei Tang, Elan D. Louis, Karen Ma, Rachel Babji, Matthew Balatbat, Etty Cortes, Jean-Paul G. Vonsattel, Ai Yamamoto, David Sulzer, Phyllis L. Faust
Mutant BRAF V600E protein in ganglioglioma is predominantly expressed by neuronal tumor cells
Christian Koelsche, Adelheid Wöhrer, Astrid Jeibmann, Jens Schittenhelm, Genevieve Schindler, Matthias Preusser, Felix Lasitschka, Andreas von Deimling, David Capper
BRAFV600E mutation is a negative prognosticator in pediatric ganglioglioma
Sonika Dahiya, Devon H. Haydon, David Alvarado, Christina A. Gurnett, David H. Gutmann, Jeffrey R. Leonard
VE1 immunohistochemistry in pituitary adenomas is not associated with BRAF V600E mutation
Jan Sperveslage, Midea Gierke, David Capper, Jürgen Honegger, Bence Sipos, Rudi Beschorner, Jens Schittenhelm
Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays
Volker Hovestadt, Marc Remke, Marcel Kool, Torsten Pietsch, Paul A. Northcott, Roger Fischer, Florence M. G. Cavalli, Vijay Ramaswamy, Marc Zapatka, Guido Reifenberger, Stefan Rutkowski, Matthias Schick, Melanie Bewerunge-Hudler, Andrey Korshunov, Peter Lichter, Michael D. Taylor, Stefan M. Pfister, David T. W. Jones
Recessive desmin-null muscular dystrophy with central nuclei and mitochondrial abnormalities
Matthew Henderson, Liesbeth De Waele, Judith Hudson, Michelle Eagle, Caroline Sewry, Julie Marsh, Richard Charlton, Langping He, Emma L. Blakely, Iain Horrocks, William Stewart, Robert W. Taylor, Cheryl Longman, Kate Bushby, Rita Barresi