Issue 3/2012
Content (13 Articles)
The genetics and neuropathology of neurodegenerative disorders: perspectives and implications for research and clinical practice
Vivianna M. Van Deerlin
The genetics and neuropathology of Alzheimer’s disease
Gerard D. Schellenberg, Thomas J. Montine
The genetics and neuropathology of amyotrophic lateral sclerosis
Ammar Al-Chalabi, Ashley Jones, Claire Troakes, Andrew King, Safa Al-Sarraj, Leonard H. van den Berg
The genetics and neuropathology of frontotemporal lobar degeneration
Anne Sieben, Tim Van Langenhove, Sebastiaan Engelborghs, Jean-Jacques Martin, Paul Boon, Patrick Cras, Peter-Paul De Deyn, Patrick Santens, Christine Van Broeckhoven, Marc Cruts
Mechanisms of disease in frontotemporal lobar degeneration: gain of function versus loss of function effects
Glenda Halliday, Eileen H. Bigio, Nigel J. Cairns, Manuela Neumann, Ian R. A. Mackenzie, David M. A. Mann
Localization of fused in sarcoma (FUS) protein to the post-synaptic density in the brain
Naoya Aoki, Shinji Higashi, Ito Kawakami, Zen Kobayashi, Masato Hosokawa, Omi Katsuse, Takashi Togo, Yoshio Hirayasu, Haruhiko Akiyama
Targeting intracerebral inflammation in multiple sclerosis: is it feasible?
Hans Lassmann
Fingolimod attenuates ceramide-induced blood–brain barrier dysfunction in multiple sclerosis by targeting reactive astrocytes
Ruben van Doorn, Philip G. Nijland, Nick Dekker, Maarten E. Witte, Melissa A. Lopes-Pinheiro , Bert van het Hof, Gijs Kooij, Arie Reijerkerk, Christine Dijkstra, Paul van van der Valk, Jack van Horssen, Helga E. de Vries
Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination
Wolfgang Brück, Ramona Pförtner, Trinh Pham, Jingya Zhang, Liat Hayardeny, Victor Piryatinsky, Uwe-Karsten Hanisch, Tommy Regen, Denise van Rossum, Lars Brakelmann, Karin Hagemeier, Tanja Kuhlmann, Christine Stadelmann, Gareth R. John, Nadine Kramann, Christiane Wegner
NF-κB contributes to the detrimental effects of social isolation after experimental stroke
Venugopal Reddy Venna, Gillian Weston, Sharon E. Benashski, Sami Tarabishy, Fudong Liu, Jun Li, Lisa H. Conti, Louise D. McCullough
K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
Dong-Anh Khuong-Quang, Pawel Buczkowicz, Patricia Rakopoulos, Xiao-Yang Liu, Adam M. Fontebasso, Eric Bouffet, Ute Bartels, Steffen Albrecht, Jeremy Schwartzentruber, Louis Letourneau, Mathieu Bourgey, Guillaume Bourque, Alexandre Montpetit, Genevieve Bourret, Pierre Lepage, Adam Fleming, Peter Lichter, Marcel Kool, Andreas von Deimling, Dominik Sturm, Andrey Korshunov, Damien Faury, David T. Jones, Jacek Majewski, Stefan M. Pfister, Nada Jabado, Cynthia Hawkins
Low rate of R132H IDH1 mutation in infratentorial and spinal cord grade II and III diffuse gliomas
Benjamin Ellezam, Brett J. Theeler, Tobias Walbert, Aaron G. Mammoser, Craig Horbinski, Bette K. Kleinschmidt-DeMasters, Arie Perry, Vinay Puduvalli, Gregory N. Fuller, Janet M. Bruner, Kenneth D. Aldape