Issue 1/2019
Content (14 Articles)
C9orf72-FTD/ALS pathogenesis: evidence from human neuropathological studies
Sarat C. Vatsavayai, Alissa L. Nana, Jennifer S. Yokoyama, William W. Seeley
Neurons selectively targeted in frontotemporal dementia reveal early stage TDP-43 pathobiology
Alissa L. Nana, Manu Sidhu, Stephanie E. Gaus, Ji-Hye L. Hwang, Libo Li, Youngsoon Park, Eun-Joo Kim, Lorenzo Pasquini, Isabel E. Allen, Katherine P. Rankin, Gianina Toller, Joel H. Kramer, Daniel H. Geschwind, Giovanni Coppola, Eric J. Huang, Lea T. Grinberg, Bruce L. Miller, William W. Seeley
Mitochondria, ER, and nuclear membrane defects reveal early mechanisms for upper motor neuron vulnerability with respect to TDP-43 pathology
Mukesh Gautam, Javier H. Jara, Nuran Kocak, Lauren E. Rylaarsdam, Ki Dong Kim, Eileen H. Bigio, P. Hande Özdinler
Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia
Ethan G. Geier, Mathieu Bourdenx, Nadia J. Storm, J. Nicholas Cochran, Daniel W. Sirkis, Ji-Hye Hwang, Luke W. Bonham, Eliana Marisa Ramos, Antonio Diaz, Victoria Van Berlo, Deepika Dokuru, Alissa L. Nana, Anna Karydas, Maureen E. Balestra, Yadong Huang, Silvia P. Russo, Salvatore Spina, Lea T. Grinberg, William W. Seeley, Richard M. Myers, Bruce L. Miller, Giovanni Coppola, Suzee E. Lee, Ana Maria Cuervo, Jennifer S. Yokoyama
The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer’s disease
Hlin Kvartsberg, Tammaryn Lashley, Christina E. Murray, Gunnar Brinkmalm, Nicholas C. Cullen, Kina Höglund, Henrik Zetterberg, Kaj Blennow, Erik Portelius
Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson’s disease pathogenesis
Craig D. Hughes, Minee L. Choi, Mina Ryten, Lee Hopkins, Anna Drews, Juan A. Botía, Maria Iljina, Margarida Rodrigues, Sarah A. Gagliano, Sonia Gandhi, Clare Bryant, David Klenerman
Correction to: Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson’s disease pathogenesis
Craig D. Hughes, Minee L. Choi, Mina Ryten, Lee Hopkins, Anna Drews, Juan A. Botía, Maria Iljina, Margarida Rodrigues, Sarah A. Gagliano, Sonia Gandhi, Clare Bryant, David Klenerman
Structure and evolution of double minutes in diagnosis and relapse brain tumors
Ke Xu, Liang Ding, Ti-Cheng Chang, Ying Shao, Jason Chiang, Heather Mulder, Shuoguo Wang, Tim I. Shaw, Ji Wen, Laura Hover, Clay McLeod, Yong-Dong Wang, John Easton, Michael Rusch, James Dalton, James R. Downing, David W. Ellison, Jinghui Zhang, Suzanne J. Baker, Gang Wu
The genetic landscape of gliomas arising after therapeutic radiation
Giselle Y. López, Jessica Van Ziffle, Courtney Onodera, James P. Grenert, Iwei Yeh, Boris C. Bastian, Jennifer Clarke, Nancy Ann Oberheim Bush, Jennie Taylor, Susan Chang, Nicholas Butowski, Anuradha Banerjee, Sabine Mueller, Cassie Kline, Joseph Torkildson, David Samuel, Aleli Siongco, Corey Raffel, Nalin Gupta, Sandeep Kunwar, Praveen Mummaneni, Manish Aghi, Philip Theodosopoulos, Mitchel Berger, Joanna J. Phillips, Melike Pekmezci, Tarik Tihan, Andrew W. Bollen, Arie Perry, David A. Solomon
Rapid lymphatic efflux limits cerebrospinal fluid flow to the brain
Qiaoli Ma, Miriam Ries, Yann Decker, Andreas Müller, Chantal Riner, Arno Bücker, Klaus Fassbender, Michael Detmar, Steven T. Proulx
“Minimal change” multiple system atrophy with limbic-predominant α-synuclein pathology
Shunsuke Koga, Dennis W. Dickson
Atypical parkinsonism of progressive supranuclear palsy–parkinsonism (PSP-P) phenotype with rare variants in FBXO7 and VPS35 genes associated with Lewy body pathology
Kateřina Menšíková, Lucie Tučková, Kristýna Kolařiková, Tereza Bartoníková, Radek Vodička, Jiri Ehrmann, Radek Vrtěl, Martin Procházka, Petr Kaňovský, Gabor G. Kovacs
ETMR-like infantile cerebellar embryonal tumors in the extended morphologic spectrum of DICER1-related tumors
Emmanuelle Uro-Coste, Julien Masliah-Planchon, Aurore Siegfried, Maud Blanluet, Sander Lambo, Marcel Kool, Thomas Roujeau, Sergio Boetto, Gilles Palenzuela, Anne-Isabelle Bertozzi, Marion Gambart, Isabelle Coupier, Isabelle Oliver-Petit, Lisa Golmard, Sophie Julia, Fréderique Savagner, Badreddine Mohand-Oumoussa, Arnault Tauziede-Espariat, Marie-Bernadette Delisle, Dominique Figarella-Branger, Franck Bourdeaut, Valérie Rigau
Chromosome arm 1q gain is an adverse prognostic factor in localized and diffuse leptomeningeal glioneuronal tumors with BRAF gene fusion and 1p deletion
Jason Chiang, James Dalton, Santhosh A. Upadhyaya, Zoltán Patay, Ibrahim Qaddoumi, Xiaoyu Li, Annette D. Segura, Suash Sharma, Azzam Ismail, Sheila A. Shurtleff, Susana C. Raimondi