Skip to main content
Top
Published in: Digestive Diseases and Sciences 10/2006

01-10-2006 | Case Report

Spontaneous Rupture of a True Splenic Cyst Diagnosed by Laparoscopy

Authors: A. Karasakalides, E. Ganas, S. Triantafillidou, D. Lagonidis, L. Papapavlou, G. Nakos

Published in: Digestive Diseases and Sciences | Issue 10/2006

Login to get access

Excerpt

Splenic rupture is described in the literature following trauma and has an approximately 30% occurrence following blunt abdominal injury [1]. On the other hand, nontraumatic or spontaneous rupture of the spleen is uncommon and when it occurs usually involves some type of underlying pathology [2, 3]. Conditions reported to be associated with nontraumatic splenic rupture include infectious (infectious mononucleosis, viral hepatitis, malaria), malignant (lymphoma, leukemia) hematological (hemophilia, hemolytic anemia), and miscellaneous (sarcoidosis, amyloidosis, splenic vein thrombosis, splenic infarction, splenic aneurysm, and splenic cysts) [410]. Diagnosing spontaneous rupture of a splenic cyst is not easy because there is a wide variety of signs and symptoms which tend to blur the diagnostic picture [1]. The presenting symptoms may mimic a variety of pathologic conditions, including myocardial infarct, pulmonary embolism, acute appendicitis, diverticulitis, and ectopic pregnancy [1113]. Sometimes spontaneous rupture of a splenic cyst is not considered in the differential diagnosis of acute abdominal pain and this can have devastating consequences. In the majority of cases, the clinical findings and the noninvasive imaging modalities (plain abdominal x-rays, U/S, and CT scan) provide enough information to assist the clinician in ascertaining a correct diagnosis. However, at times, the clinical presentation is confusing and discrepancies may exist between a vague clinical picture and the imaging results. Diagnostic laparoscopy in such cases may be very helpful in clarifying the problem thereby leading to a prompt diagnosis. We present a 35-year-old female who had an unclear clinical picture, and although she underwent an assortment of noninvasive imaging modalities including U/S and CT scan, diagnostic laparoscopy was necessary to provide the definitive diagnosis. We present this as a case of a spontaneous rupture of a true splenic cyst, which is a rare clinical entity, as well as stressing the importance of laparoscopy as a diagnostic tool. …
Literature
1.
go back to reference Lieberman ME, Andrew Levitt M (1989) Spontaneous rupture of the spleen. A case report and literature review. Am J Emerg Med 7:28–31PubMedCrossRef Lieberman ME, Andrew Levitt M (1989) Spontaneous rupture of the spleen. A case report and literature review. Am J Emerg Med 7:28–31PubMedCrossRef
2.
go back to reference Buciuto R, Kald A, Borch K (1992) Spontaneous rupture of the spleen. Case report. Eur J Surg 158:129–130PubMed Buciuto R, Kald A, Borch K (1992) Spontaneous rupture of the spleen. Case report. Eur J Surg 158:129–130PubMed
3.
go back to reference Chi-Ming L, Siu-Tsan Y, Wai-Key Y (1998) Hemoperitoneum caused by spontaneous rupture of a true splenic cyst. Hepato-Gastroenterology 45:1884–1886 Chi-Ming L, Siu-Tsan Y, Wai-Key Y (1998) Hemoperitoneum caused by spontaneous rupture of a true splenic cyst. Hepato-Gastroenterology 45:1884–1886
4.
go back to reference Lazaro EJ, Ong F, Parmer LP (1970) Splenic rupture masquerading as acute appendicitis. Am Surg 36:705–708PubMed Lazaro EJ, Ong F, Parmer LP (1970) Splenic rupture masquerading as acute appendicitis. Am Surg 36:705–708PubMed
5.
go back to reference Sharma OP (1967) Splenic rupture of sarcoidosis. Rupture of an unusual case. Am Rev Respir Dis 96:101–102PubMed Sharma OP (1967) Splenic rupture of sarcoidosis. Rupture of an unusual case. Am Rev Respir Dis 96:101–102PubMed
6.
go back to reference Horie Y, Takeakis Hirayama C, et al. (1982) Spontaneous rupture of the spleen secondary to metastatic hepatocellular carcinoma. A report of a case and review of the literature. Am J Gastroenterol 77:882–884PubMed Horie Y, Takeakis Hirayama C, et al. (1982) Spontaneous rupture of the spleen secondary to metastatic hepatocellular carcinoma. A report of a case and review of the literature. Am J Gastroenterol 77:882–884PubMed
7.
go back to reference Fallingborg J, Lawstfen J, Jakobsen J (1985) Atraumatic rupture of the spleen in periarteritis nodosa. Acta Chir Scand 151:85–87PubMed Fallingborg J, Lawstfen J, Jakobsen J (1985) Atraumatic rupture of the spleen in periarteritis nodosa. Acta Chir Scand 151:85–87PubMed
8.
go back to reference Nichols T, Wright FM, Pyeatte J, et al. (1981) Spontaneous rupture of the spleen. An unusual complication of Chrohn's disease. Am J Gastroenterol 75:226–228PubMed Nichols T, Wright FM, Pyeatte J, et al. (1981) Spontaneous rupture of the spleen. An unusual complication of Chrohn's disease. Am J Gastroenterol 75:226–228PubMed
9.
go back to reference Rest JG, Seid AS, Rogers D, et al. (1985) Pathologic rupture of the spleen due to salmonella Dublin infection. J Trauma 25:366–368PubMed Rest JG, Seid AS, Rogers D, et al. (1985) Pathologic rupture of the spleen due to salmonella Dublin infection. J Trauma 25:366–368PubMed
10.
go back to reference Robbins FG, Yellin AE, Lingua RW, Craig JR, Turrill FL, Mikkelsen WP (1978) Splenic epidermoid cysts. Ann Surg 187(3):231–235PubMedCrossRef Robbins FG, Yellin AE, Lingua RW, Craig JR, Turrill FL, Mikkelsen WP (1978) Splenic epidermoid cysts. Ann Surg 187(3):231–235PubMedCrossRef
11.
go back to reference Jahadi MR, Bailey W, Crenshaw A (1975) A traumatic splenic rupture simulating ruptured sigmoid diverticulitis. Dis Colon Rectum 18:59–61PubMed Jahadi MR, Bailey W, Crenshaw A (1975) A traumatic splenic rupture simulating ruptured sigmoid diverticulitis. Dis Colon Rectum 18:59–61PubMed
12.
go back to reference Drapanas T, Yates AJ, Brickman R, et al. (1969) The syndrome of occult rupture of the spleen. Arch Surg 99:298–301PubMed Drapanas T, Yates AJ, Brickman R, et al. (1969) The syndrome of occult rupture of the spleen. Arch Surg 99:298–301PubMed
13.
go back to reference Kubak AJ, Weiss M, Sturman HG (1954) Ruptured spleen simulating ectopic pregnancy. Am J Obstet Gynecol 67:422–426 Kubak AJ, Weiss M, Sturman HG (1954) Ruptured spleen simulating ectopic pregnancy. Am J Obstet Gynecol 67:422–426
14.
go back to reference Fowler RH (1953) Nonparasitic benign cystic tumors of the spleen. Surg Gynecol Obstet 96(Suppl):209–227 Fowler RH (1953) Nonparasitic benign cystic tumors of the spleen. Surg Gynecol Obstet 96(Suppl):209–227
15.
go back to reference Garvin DF, King FM (1981) Cysts and nonlymphomatous tumors of the spleen. Pathol Annu 16:61–80PubMed Garvin DF, King FM (1981) Cysts and nonlymphomatous tumors of the spleen. Pathol Annu 16:61–80PubMed
16.
go back to reference Park JY, Song KT (1971) Splenic cyst. A case report and review of the literature. Am Surg 37:544–547PubMed Park JY, Song KT (1971) Splenic cyst. A case report and review of the literature. Am Surg 37:544–547PubMed
17.
go back to reference Nakae Y, Hayakawa T, Kondo T, et al. (1991) Epidermoid cyst occurring in a pancreatic accessory spleen. J Clin Gastroenterol 13(3):362–365PubMed Nakae Y, Hayakawa T, Kondo T, et al. (1991) Epidermoid cyst occurring in a pancreatic accessory spleen. J Clin Gastroenterol 13(3):362–365PubMed
18.
go back to reference Fowler RH (1940) Cystic tumours of the spleen. Int Abstr Surg 70:213–223 Fowler RH (1940) Cystic tumours of the spleen. Int Abstr Surg 70:213–223
19.
go back to reference Warnke RA, Weiss LM, Chan JKC, Cleary ML, Dorfman RF (1995) Tumors of the lymph nodes and spleen. In: Rosai J (ed) Atlas of tumor pathology. Third Series, Fascicle 14. Armed Forces Institute of Pathology, Washington, DC, pp 506–509 Warnke RA, Weiss LM, Chan JKC, Cleary ML, Dorfman RF (1995) Tumors of the lymph nodes and spleen. In: Rosai J (ed) Atlas of tumor pathology. Third Series, Fascicle 14. Armed Forces Institute of Pathology, Washington, DC, pp 506–509
20.
go back to reference Sakamoto Y, Yunotani S, Edakuni G, Mori M, Iyama A, Miyazaki K (1999) Laparoscopic splenectomy for a giant splenic epidermoid cyst: Report of a case. Surg Today 29:1268–1272PubMedCrossRef Sakamoto Y, Yunotani S, Edakuni G, Mori M, Iyama A, Miyazaki K (1999) Laparoscopic splenectomy for a giant splenic epidermoid cyst: Report of a case. Surg Today 29:1268–1272PubMedCrossRef
21.
go back to reference Arda IS, Tuzun M, Hicsonmez A (2005) Epidermoid cyst of the spleen with elevated levels of CA125 and carcino-embryonic antigen. Eur J Pediatr 164(2):108PubMedCrossRef Arda IS, Tuzun M, Hicsonmez A (2005) Epidermoid cyst of the spleen with elevated levels of CA125 and carcino-embryonic antigen. Eur J Pediatr 164(2):108PubMedCrossRef
22.
go back to reference Lieto E, Castellano P, Ferrara Orditura P, De Vita F, Galizia G (2003) Normal interleukin-10 serum level opposed to high serum levels of carbohydrate antigen 19-9 and cancer antigens 125 and 50 in a case of true splenic cyst. Arch Med Res 34(5):444 Lieto E, Castellano P, Ferrara Orditura P, De Vita F, Galizia G (2003) Normal interleukin-10 serum level opposed to high serum levels of carbohydrate antigen 19-9 and cancer antigens 125 and 50 in a case of true splenic cyst. Arch Med Res 34(5):444
23.
go back to reference Galizia G, Lieto E, Ferraraccio F, Castellano P, De Vita F, Orditura M, Romano C, Pignatelli C (2003) A true splenic cyst producing carbohydrate antigen 19-9 and cancer antigens 50 and 125, but not interleukin 10 Dig Surg 20(1):71–74PubMedCrossRef Galizia G, Lieto E, Ferraraccio F, Castellano P, De Vita F, Orditura M, Romano C, Pignatelli C (2003) A true splenic cyst producing carbohydrate antigen 19-9 and cancer antigens 50 and 125, but not interleukin 10 Dig Surg 20(1):71–74PubMedCrossRef
24.
go back to reference Matsubayashi H, Kuraoka K, Kobayashi Y, Yokota T, Iiri Y, Shichijo K, Tada T, Satoh K, Kijima H (2001) Ruptured epidermoid cyst and haematoma of spleen: A diagnostic clue of high levels of serum carcinoembryonic antigen, carbohydrate antigen 19-9 and Sialyl Lewis x. Dig Liver Dis 33(7):595–599PubMedCrossRef Matsubayashi H, Kuraoka K, Kobayashi Y, Yokota T, Iiri Y, Shichijo K, Tada T, Satoh K, Kijima H (2001) Ruptured epidermoid cyst and haematoma of spleen: A diagnostic clue of high levels of serum carcinoembryonic antigen, carbohydrate antigen 19-9 and Sialyl Lewis x. Dig Liver Dis 33(7):595–599PubMedCrossRef
25.
go back to reference Trompetas V, Panagopoulos E, Priovolou-Papaevangelou M, Ramantanis G (2002) Giant benign true cyst of the spleen with high serum level of CA 19-9. Eur J Gastroenterol Hepatol 14(1):85–88PubMedCrossRef Trompetas V, Panagopoulos E, Priovolou-Papaevangelou M, Ramantanis G (2002) Giant benign true cyst of the spleen with high serum level of CA 19-9. Eur J Gastroenterol Hepatol 14(1):85–88PubMedCrossRef
26.
go back to reference Madia C, Lumachi F, Veroux M, Fiamingo P, Gringeri E, Brolese A, Zanus G, CilloU D’Amico CF (2003) Giant splenic epithelial cyst with elevated serum markers CEA and CA 19-9 levels: An incidental association? Anticancer Res 23(1B):773–776PubMed Madia C, Lumachi F, Veroux M, Fiamingo P, Gringeri E, Brolese A, Zanus G, CilloU D’Amico CF (2003) Giant splenic epithelial cyst with elevated serum markers CEA and CA 19-9 levels: An incidental association? Anticancer Res 23(1B):773–776PubMed
27.
go back to reference Van lacum MW, Hessels RA, Kremer GD, Jaspers CA (2000) A splenic cyst and a high serum CA 19-9: a case report. Eur J Intern Med 11(2):104–107PubMedCrossRef Van lacum MW, Hessels RA, Kremer GD, Jaspers CA (2000) A splenic cyst and a high serum CA 19-9: a case report. Eur J Intern Med 11(2):104–107PubMedCrossRef
28.
go back to reference Morgenstern L (2002) Nonparasitic splenic cysts: pathogenesis, classification and treatment. J Am Coll Surg 194:306–314PubMedCrossRef Morgenstern L (2002) Nonparasitic splenic cysts: pathogenesis, classification and treatment. J Am Coll Surg 194:306–314PubMedCrossRef
29.
go back to reference Burrig KF (1988) Epithelial (true) splenic cysts. Pathogenesis of the mesothelial and so-called epidermoid cyst of the spleen. Am J Surg Pathol 12:275–281PubMedCrossRef Burrig KF (1988) Epithelial (true) splenic cysts. Pathogenesis of the mesothelial and so-called epidermoid cyst of the spleen. Am J Surg Pathol 12:275–281PubMedCrossRef
30.
go back to reference Hyun BH, Varga CF, Rubin RJ (1972) Spontaneous and pathologic rupture of the spleen. Arch Surg 104:652–657PubMed Hyun BH, Varga CF, Rubin RJ (1972) Spontaneous and pathologic rupture of the spleen. Arch Surg 104:652–657PubMed
31.
go back to reference VanLandingham SB, Rawls DE, Roberts JW (1984) Pathological rupture of the spleen associated with hepatitis A. Arch Surg 119:224–225 VanLandingham SB, Rawls DE, Roberts JW (1984) Pathological rupture of the spleen associated with hepatitis A. Arch Surg 119:224–225
32.
go back to reference Hynes EH, Silverstein NM, Fawcett JF (1964) Spontaneous rupture of the spleen in leukemia. Cancer 17:1356–1360PubMedCrossRef Hynes EH, Silverstein NM, Fawcett JF (1964) Spontaneous rupture of the spleen in leukemia. Cancer 17:1356–1360PubMedCrossRef
33.
go back to reference Andrews DF, Hernandez R, Grafton W, et al. (1980) Pathologic rupture of the spleen in nonHodgkin's lymphoma. Arch Intern Med 140:119–120PubMedCrossRef Andrews DF, Hernandez R, Grafton W, et al. (1980) Pathologic rupture of the spleen in nonHodgkin's lymphoma. Arch Intern Med 140:119–120PubMedCrossRef
34.
go back to reference Musy PA, Roche B, Belli D, Bugmann P, Nussle D, LeCoultre C (1992) Splenic cysts in pediatric patients: A report on 8 cases and review of the literature. Eur J Pediatr Surg 2:137–140PubMedCrossRef Musy PA, Roche B, Belli D, Bugmann P, Nussle D, LeCoultre C (1992) Splenic cysts in pediatric patients: A report on 8 cases and review of the literature. Eur J Pediatr Surg 2:137–140PubMedCrossRef
35.
go back to reference Walz MK, Metz KA, Eigler FW (1991) Splenic cysts. Their morphology, diagnosis and therapy. Dtsch Med Wochenschr 116:1377–1381PubMed Walz MK, Metz KA, Eigler FW (1991) Splenic cysts. Their morphology, diagnosis and therapy. Dtsch Med Wochenschr 116:1377–1381PubMed
36.
go back to reference Till H, Schaarschmidt K (2004) Partial laparoscopic decapsulation of congenital splenic cysts. A medium-term evaluation proves the efficiency in children Surg Endosc 18:626–628 Till H, Schaarschmidt K (2004) Partial laparoscopic decapsulation of congenital splenic cysts. A medium-term evaluation proves the efficiency in children Surg Endosc 18:626–628
37.
go back to reference Gianom D, Wildisen A, Hotz T, Goti F, Decurtins M (2003) Open and laparoscopic treatment of nonparasitic splenic cysts. Dig Surg 20:74–78PubMedCrossRef Gianom D, Wildisen A, Hotz T, Goti F, Decurtins M (2003) Open and laparoscopic treatment of nonparasitic splenic cysts. Dig Surg 20:74–78PubMedCrossRef
38.
go back to reference Moir C, Guttman F, Jequier S, Sonnino R, Youssef S (1989) Splenic cysts: aspiration, sclerosis, or resection. J Pediatr Surg 24:646–648PubMedCrossRef Moir C, Guttman F, Jequier S, Sonnino R, Youssef S (1989) Splenic cysts: aspiration, sclerosis, or resection. J Pediatr Surg 24:646–648PubMedCrossRef
39.
go back to reference Smith ST, Scott DJ, Burdick JS, Rege RV, Jones DB (2001) Laparoscopic marsupialization and hemisplenectomy for splenic cysts. J Laparoendosc Adv Surg Tech 11:243–249CrossRef Smith ST, Scott DJ, Burdick JS, Rege RV, Jones DB (2001) Laparoscopic marsupialization and hemisplenectomy for splenic cysts. J Laparoendosc Adv Surg Tech 11:243–249CrossRef
40.
go back to reference Touloukian RJ, Maharaj A, Ghoussoub R, Reyes M (1997) Partial decapsulation of splenic epithelial cysts: studies on etiology and outcome. J Pediatr Surg 32:272–274PubMedCrossRef Touloukian RJ, Maharaj A, Ghoussoub R, Reyes M (1997) Partial decapsulation of splenic epithelial cysts: studies on etiology and outcome. J Pediatr Surg 32:272–274PubMedCrossRef
41.
go back to reference Bird D, Kelly M, Baird RN (1979) Spontaneous rupture of the normal spleen: Diagnosis by computerized tomography. Br J Surg 66:598PubMed Bird D, Kelly M, Baird RN (1979) Spontaneous rupture of the normal spleen: Diagnosis by computerized tomography. Br J Surg 66:598PubMed
42.
go back to reference Bundy AL, Scott M, Druckman D, Siegal TL, Verdi TA (1985) Delayed and occult splenic rupture. Comput Radiol 9:299–305PubMedCrossRef Bundy AL, Scott M, Druckman D, Siegal TL, Verdi TA (1985) Delayed and occult splenic rupture. Comput Radiol 9:299–305PubMedCrossRef
43.
go back to reference DeGraaf J, Pijpers PM (1987) Spontaneous rupture of the spleen in third trimester of pregnancy. Report of a case and review of the literature. Eur J Obstet Gynecol Reprod Biol 25:243–247 DeGraaf J, Pijpers PM (1987) Spontaneous rupture of the spleen in third trimester of pregnancy. Report of a case and review of the literature. Eur J Obstet Gynecol Reprod Biol 25:243–247
44.
go back to reference Kianmanesh R, Aguirre HI, Enjaume F, Valverde A, Brugiere O, Vacher B, Bleichner G (2003) Spontaneous splenic rupture: Report of three new cases and review of the literature. Ann Chir 128(5):303–309PubMedCrossRef Kianmanesh R, Aguirre HI, Enjaume F, Valverde A, Brugiere O, Vacher B, Bleichner G (2003) Spontaneous splenic rupture: Report of three new cases and review of the literature. Ann Chir 128(5):303–309PubMedCrossRef
45.
go back to reference Yagmur Y, Hamdi Kara I, Aldemir M, Büyükbayram H, Tacyildiz IH, Keles C (2000) Spontaneous rupture of malarial spleen: two case reports and review of literature. Crit Care 4(5):309–313PubMedCrossRef Yagmur Y, Hamdi Kara I, Aldemir M, Büyükbayram H, Tacyildiz IH, Keles C (2000) Spontaneous rupture of malarial spleen: two case reports and review of literature. Crit Care 4(5):309–313PubMedCrossRef
46.
go back to reference Bernat S, Boyero R, Guinot M, Lopez F, Gozalbo T, Canigral G (1998) Pathologic rupture of the spleen as the initial manifestation in acute lymphoblastic leukemia. Haematologica 83(8):760–761PubMed Bernat S, Boyero R, Guinot M, Lopez F, Gozalbo T, Canigral G (1998) Pathologic rupture of the spleen as the initial manifestation in acute lymphoblastic leukemia. Haematologica 83(8):760–761PubMed
Metadata
Title
Spontaneous Rupture of a True Splenic Cyst Diagnosed by Laparoscopy
Authors
A. Karasakalides
E. Ganas
S. Triantafillidou
D. Lagonidis
L. Papapavlou
G. Nakos
Publication date
01-10-2006
Published in
Digestive Diseases and Sciences / Issue 10/2006
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-006-9076-6

Other articles of this Issue 10/2006

Digestive Diseases and Sciences 10/2006 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.