Skip to main content
Top
Published in: Journal of Infection and Chemotherapy 6/2011

01-12-2011 | Case Report

Splenic abscess caused by MRSA developing in an infarcted area: case report and literature review

Authors: Ferhat Arslan, Ayse Batirel, Fehmi Tabak, Ali Mert

Published in: Journal of Infection and Chemotherapy | Issue 6/2011

Login to get access

Abstract

We report a case of a 41-year-old man with a splenic abscess caused by methicillin-resistant Staphylococcus aureus (MRSA). He had been treated with antimicrobials and corticosteroids for interstitial pneumonia caused by Mycoplasma pneumoniae and hemolytic anemia. He developed catheter-related (MRSA) bacteremia during his stay in the ICU and was treated with teicoplanin for 2 weeks. After 4 weeks of outpatient follow-up, he was readmitted to the hospital with fever and pain in the left upper quadrant. A thoracoabdominal CT scan showed subcapsular collection in areas of splenic infarction that had been detected on his first admission. CT-guided percutaneous aspiration resulted in the isolation of MRSA. The patient was treated successfully with teicoplanin for 6 weeks. Our aim in presenting this quite rare case is to highlight the tendency of infarcts that develop as a result of hemolytic attacks during systemic infections to be a focus of infection for nosocomial bacteremia.
Literature
1.
go back to reference Ting W, Silverman NA, Arzouman DA, Levitsky S. Splenic septic emboli in endocarditis. Circulation 1990;82(IV):105–109. Ting W, Silverman NA, Arzouman DA, Levitsky S. Splenic septic emboli in endocarditis. Circulation 1990;82(IV):105–109.
2.
go back to reference Robinson SL, Saxe JM, Lucas CE, Arbulu A, Ledgerwood AM, Lucas WF. Splenic abscess associated with endocarditis. Surgery (St. Louis). 1992;112:781. Robinson SL, Saxe JM, Lucas CE, Arbulu A, Ledgerwood AM, Lucas WF. Splenic abscess associated with endocarditis. Surgery (St. Louis). 1992;112:781.
3.
go back to reference Johnson JD, Raff MJ, Barnwell PA, Chun CH. Splenic abscess complicating infectious endocarditis. Arch Intern Med. 1983;143:906.PubMedCrossRef Johnson JD, Raff MJ, Barnwell PA, Chun CH. Splenic abscess complicating infectious endocarditis. Arch Intern Med. 1983;143:906.PubMedCrossRef
4.
go back to reference Ebright JR, Alam E, Ahmed H, Tucker R, Abrams J, Levine D. Splenic infarction and abscess in the setting of infective endocarditis. Infect Dis Clin Pract. 2007;15:17.CrossRef Ebright JR, Alam E, Ahmed H, Tucker R, Abrams J, Levine D. Splenic infarction and abscess in the setting of infective endocarditis. Infect Dis Clin Pract. 2007;15:17.CrossRef
5.
go back to reference Ozkurt Z, Erkut B, Kadanali A, Ates A, Yekeler I. Nosocomial methicillin-resistant Staphylococcus aureus endocarditis with splenic abscess in a pregnant woman. Jpn J Infect Dis. 2005;58:323–5.PubMed Ozkurt Z, Erkut B, Kadanali A, Ates A, Yekeler I. Nosocomial methicillin-resistant Staphylococcus aureus endocarditis with splenic abscess in a pregnant woman. Jpn J Infect Dis. 2005;58:323–5.PubMed
6.
go back to reference Izumikawa K, Morinaga Y, Izumikawa K, Hara K, Kohno S. A case of splenic abscess during treatment of interstitial pneumonia. Jpn J Infect Dis. 2006;59:320–2.PubMed Izumikawa K, Morinaga Y, Izumikawa K, Hara K, Kohno S. A case of splenic abscess during treatment of interstitial pneumonia. Jpn J Infect Dis. 2006;59:320–2.PubMed
7.
go back to reference Llenas-García J, Fernández-Ruiz M, Caurcel L, Enguita-Valls A, Vila-Santos J, Guerra-Vales JM. Splenic abscess: a review of 22 cases in a single institution. Eur J Intern Med. 2009;20:537–9.PubMedCrossRef Llenas-García J, Fernández-Ruiz M, Caurcel L, Enguita-Valls A, Vila-Santos J, Guerra-Vales JM. Splenic abscess: a review of 22 cases in a single institution. Eur J Intern Med. 2009;20:537–9.PubMedCrossRef
9.
go back to reference Arruabarrena I, Bermejo MC, Ojeda E, Cosme A, Garmendia G. Incidence and clinical features of splenic abscesses, with special reference to tuberculous etiology in a general hospital. Gastroenterol Hepatol. 1998;21:479–82.PubMed Arruabarrena I, Bermejo MC, Ojeda E, Cosme A, Garmendia G. Incidence and clinical features of splenic abscesses, with special reference to tuberculous etiology in a general hospital. Gastroenterol Hepatol. 1998;21:479–82.PubMed
10.
go back to reference Chun CH, Raff MJ, Contreras L, Varghese R, Waterman N, Daffner R, et al. Splenic abscess. Medicine (Baltim). 1980;59:50–65. Chun CH, Raff MJ, Contreras L, Varghese R, Waterman N, Daffner R, et al. Splenic abscess. Medicine (Baltim). 1980;59:50–65.
11.
go back to reference Weinstein L. Life-threatening complications of infective endocarditis and their management. Arch Intern Med. 1986;146:953.PubMedCrossRef Weinstein L. Life-threatening complications of infective endocarditis and their management. Arch Intern Med. 1986;146:953.PubMedCrossRef
12.
go back to reference Altemeier WA, Culbertson WR, Fullen WD, Shook CD. Intra-abdominal abscesses. Am J Surg. 1973;125:70–9.PubMedCrossRef Altemeier WA, Culbertson WR, Fullen WD, Shook CD. Intra-abdominal abscesses. Am J Surg. 1973;125:70–9.PubMedCrossRef
13.
go back to reference Fishman D, Isenberg DA. Splenic involvement in rheumatic diseases. Semin Arthritis Rheum. 1997;27:141–55.PubMedCrossRef Fishman D, Isenberg DA. Splenic involvement in rheumatic diseases. Semin Arthritis Rheum. 1997;27:141–55.PubMedCrossRef
14.
go back to reference Kapoor P, Singh E, Radhakrishnan P, Mehta P. Splenectomy in plasma cell dyscrasias: a review of the clinical practice. Am J Hematol. 2006;81:946–54.PubMedCrossRef Kapoor P, Singh E, Radhakrishnan P, Mehta P. Splenectomy in plasma cell dyscrasias: a review of the clinical practice. Am J Hematol. 2006;81:946–54.PubMedCrossRef
15.
go back to reference Kapur A, Vasudeva R, Howden CW. Candida splenic abscess in the absence of obvious immunodeficiency. Am J Gastroenterol. 1997;92:509–12.PubMed Kapur A, Vasudeva R, Howden CW. Candida splenic abscess in the absence of obvious immunodeficiency. Am J Gastroenterol. 1997;92:509–12.PubMed
17.
go back to reference Phillips GS, Radosevich MD, Lipsett PA. Splenic abscess: another look at an old disease. Arch Surg. 1997;132:1331–6. discussion 1335–1336.PubMedCrossRef Phillips GS, Radosevich MD, Lipsett PA. Splenic abscess: another look at an old disease. Arch Surg. 1997;132:1331–6. discussion 1335–1336.PubMedCrossRef
18.
go back to reference Salvi PF, Stagnitti F, Mongardini M, Schillaci F, Stagnitti A, Chirletti P. Splenic infarction, a rare cause of acute abdomen, only seldom requires splenectomy. Case report and literature review. Ann Ital Chir. 2007;78:529–32.PubMed Salvi PF, Stagnitti F, Mongardini M, Schillaci F, Stagnitti A, Chirletti P. Splenic infarction, a rare cause of acute abdomen, only seldom requires splenectomy. Case report and literature review. Ann Ital Chir. 2007;78:529–32.PubMed
19.
go back to reference Uthman I, Khamashta M. The abdominal manifestations of the antiphospholipid syndrome. Rheumatology (Oxf). 2007;46:1641–7.CrossRef Uthman I, Khamashta M. The abdominal manifestations of the antiphospholipid syndrome. Rheumatology (Oxf). 2007;46:1641–7.CrossRef
20.
go back to reference Madani G, Papadopoulou AM, Holloway B, Robins A, Davis J, Murray D. The radiological manifestations of sickle cell disease. Clin Radiol. 2007;62:528–38.PubMedCrossRef Madani G, Papadopoulou AM, Holloway B, Robins A, Davis J, Murray D. The radiological manifestations of sickle cell disease. Clin Radiol. 2007;62:528–38.PubMedCrossRef
21.
go back to reference Obarski TP, Stoller JK, Weinstein C, Hayden S. Splenic infarction: a new thrombotic manifestation of the circulating lupus anticoagulant. Cleve Clin J Med. 1989;56:174–6.PubMed Obarski TP, Stoller JK, Weinstein C, Hayden S. Splenic infarction: a new thrombotic manifestation of the circulating lupus anticoagulant. Cleve Clin J Med. 1989;56:174–6.PubMed
22.
go back to reference Zou CC, Liang L. Multiple hypoechoic lesions in spleen and Mycoplasma pneumoniae infection. Indian Pediatr. 2005;42:379–82.PubMed Zou CC, Liang L. Multiple hypoechoic lesions in spleen and Mycoplasma pneumoniae infection. Indian Pediatr. 2005;42:379–82.PubMed
Metadata
Title
Splenic abscess caused by MRSA developing in an infarcted area: case report and literature review
Authors
Ferhat Arslan
Ayse Batirel
Fehmi Tabak
Ali Mert
Publication date
01-12-2011
Publisher
Springer Japan
Published in
Journal of Infection and Chemotherapy / Issue 6/2011
Print ISSN: 1341-321X
Electronic ISSN: 1437-7780
DOI
https://doi.org/10.1007/s10156-011-0247-9

Other articles of this Issue 6/2011

Journal of Infection and Chemotherapy 6/2011 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.