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01-07-2017 | Focus Session

Sonographic detection of open spina bifida in the first trimester: review of the literature

Authors: César Meller, Horacio Aiello, Lucas Otaño

Published in: Child's Nervous System | Issue 7/2017

Abstract

In the beginnings, sonographic diagnosis of open spina bifida (OSB) relied on the meticulous scanning of the fetal vertebrae for abnormalities but many defects were missed. After the mid-1980s, however, with the description of the intracranial findings in the second trimester (the “lemon sign” and the “banana sign”), the prenatal diagnosis of OSB was enhanced. In the last 2 decades, there has been widespread uptake of routine ultrasound examination in the first trimester of pregnancy with the purpose of the measurement of fetal crown-rump length to determine gestational age, to screen for trisomy 21 and other aneuploidies, mainly with the nuchal translucency, and for diagnosis of many major abnormalities. Many papers were published focusing on early diagnosis of myelomeningocele (MMC), and the objective of this review is to summarize the different techniques described regarding prenatal diagnosis of OSB in the first trimester of pregnancy.

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Title: Sonographic detection of open spina bifida in the first trimester: review of the literature
Authors: César Meller
Horacio Aiello
Lucas Otaño
Publication date: 01-07-2017
Publisher: Springer Berlin Heidelberg
Published in: Child's Nervous System / Issue 7/2017
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI: https://doi.org/10.1007/s00381-017-3443-9

At a glance: The STEP trials

Springer Medicine

Sonographic detection of open spina bifida in the first trimester: review of the literature

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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