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01-06-2018 | Original Article

Some epidemiological aspects of cutaneous leishmaniasis with emphasis on vectors and reservoirs of disease in the borderline of Iran and Iraq

Authors: Mohammad Moradi, Yavar Rassi, Mohammad Reza Abai, Alireza Zahraei Ramazani, Mehdi Mohebali, Sayena Rafizadeh

Published in: Journal of Parasitic Diseases | Issue 2/2018

Abstract

Cutaneous leishmaniasis (CL) is endemic and a major health problem in 17 provinces out of 31 in Iran. This study aimed to determine vectors and reservoirs of the disease using molecular techniques in the borderline of Iran and Iraq. Sand flies and rodents were sampled using sticky paper traps and metal wire live traps, respectively, in the selected villages. About 10% of archived confirmed human positive slides was randomly checked for Leishmania by PCR–RFLP assay. The female sand flies were dissected in alcohol 96% in a sterile condition, the head and two segments of the abdomen end permanently mounted for identification and the remaining of body used for DNA extraction. The direct parasitological tests were carried out on the stained slides of rodents for Leishmania as well as PCR–RFLP assay used for molecular detection of parasite. A total of 2050 sand flies were identified comprising of Phlebotomus papatasi, Sergentomyia sintoni, Se. clydei, Se. mervynae, Se. theodori, Se. dentate and Se. iranica. The Ph. papatasi was ranked as a prevailing sand fly species. Molecular tests on female sand flies revealed infection of Ph. papatasi to Leishmania major. Direct parasitology and molecular tests confirmed of 20% infection to L. major among the sole rodents species “Tatera indica”. Due to wide dispersion of rodents colonies in the area and long favorite climate condition for sand flies, the CL foci will be provided the health risk for the religious tourists.

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Title: Some epidemiological aspects of cutaneous leishmaniasis with emphasis on vectors and reservoirs of disease in the borderline of Iran and Iraq
Authors: Mohammad Moradi
Yavar Rassi
Mohammad Reza Abai
Alireza Zahraei Ramazani
Mehdi Mohebali
Sayena Rafizadeh
Publication date: 01-06-2018
Publisher: Springer India
Published in: Journal of Parasitic Diseases / Issue 2/2018
Print ISSN: 0971-7196
Electronic ISSN: 0975-0703
DOI: https://doi.org/10.1007/s12639-018-0991-1

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At a glance: The STEP trials

Springer Medicine

Abstract

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Other articles of this Issue 2/2018

Biochemical and ultrastructural changes in Raillietina echinobothrida in vitro exposed to extract of Lysimachia ramosa

Efficacy of some essential oils on Cephalopina titillator with special concern to nasal myiasis prevalence among camels and its consequent histopathological changes

Furcocercous cercariae infecting freshwater snails in Malabar: two new species from Lymnea luteola Lamarck and Gyraulus convexiusculus (Hutton)

Gross, histopathology and molecular diagnosis of oesophagostomosis in sheep

Aphelenchoides manipurensis sp. nov. (Nematoda: Tylenchina) from Manipur, India

A new species of Camallanidae (Raillet and Henry, 1917) from a siluroid catfish in Barak River, Jiribam, Manipur (India)

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