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Annals of Surgical Innovation and Research

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Open Access 01-12-2015 | Case report

Solitary scalp metastasis – a rare presentation of hepatocellular carcinoma

Authors: Duminda Subasinghe, Chathuranga Tisara Keppetiyagama, Hemantha Sudasinghe, Saman Wadanamby, Niranthi Perera, Sivasuriya Sivaganesh

Published in: Annals of Surgical Innovation and Research | Issue 1/2015

Abstract

Introduction

Hepatocellular carcinoma (HCC) is among the commonest cancers in the world. Metastasis is one of the most significant factors affecting prognosis. Common sites of extrahepatic metastases include lungs, regional lymph nodes and less commonly bone.

Case presentation

A 56-year-old male presented with a painless occipital scalp lump of three months duration, with recent rapid enlargement. His skull x-ray showed a lytic lesion over occipital bone and the contrast CT scan of the brain showed a scalp mass with destruction of the adjacent skull. Core biopsy of the lesion revealed a metastatic deposit from a hepatocellular carcinoma.

Conclusion

Primary presentation with skeletal metastases are rare in HCC with only a few reported cases. Here we report a case of HCC presenting as a solitary scalp lump.

Hsieh CT, Sun JM, Tsai WC, Tsai TH, Chiang YH, Liu MY. Skull metastasis from hepatocellular carcinoma. Acta Neurochir. 2007;149:185–90.PubMedCrossRef

Bosch FX, Ribes J, Diaz M, Cleries R. Primary liver cancer; worldwide incidence and trends. Gastroenterology. 2004;127(Suppl1):s5–s16.PubMedCrossRef

Yoshida D, Chen MN, Awaya S, Nakazawa S. Cranial metastasis of hepatocellular carcinoma in a female – case report. Neurol Med Chir (Tokyo). 1993;33:839–44.CrossRef

Fukutomi M, Yokota M, Chuman H, Harada H, Zaitsu Y, Funakoshi A, et al. Increased incidence of bone metastases in hepatocellular carcinoma. Eur J Gastroenterol Hepatol. 2001;13:1083–8.PubMedCrossRef

Murakami R, Korogi Y, Sakamoto Y, Takhashi M, Okuda T, Yasunaga T, et al. Skull metastasis from hepatocellular carcinoma. CT, MR and angiographic findings. Acta Radiol. 1995;36:597–602.PubMedCrossRef

McIver JI, Scheithauer BW, Rydberg CH, Atkinson JL. Metastatic hepatocellular carcinoma presenting as epidural hematoma:case report. Neurosurgery. 2001;49:447–9.PubMed

Chan CH, Trost N, McKelvie P, Rophael JA, Murphy MA. Unusual case of skull metastasis from hepatocellular carcinoma. ANZ J Surg. 2004;74:710–3.PubMedCrossRef

Krathen RA, Orengo IF, Rosen T. Cutaneous metastasis: a meta-analysis of data. South Med J. 2003;96:164–7.PubMedCrossRef

Casella G, Cacopardo E, Rovere G, Buda CA, Cascinu S, Baldini V. Cutaneous seeding after ultrasound-guided percutaneous ethanol injection for treatment of hepatocellular carcinoma. J Clin Ultrasound. 2001;29:354–8.PubMedCrossRef

10.

Koffi E, Moutardier V, Sauvanet A, Noun R, Flejou JF, Belghiti J. Wound recurrence after resection of hepatocellular carcinoma. Liver Tanspl Surg. 1996;2:301–3.CrossRef

11.

Amador A, Monforte NG, Bejarano N, Martí J, Artigau E, Navarro S, et al. Cutaneou metastases from hepatocellular carcinoma as the first clinical sign. J Hepatobiliary Pancreat Surg. 2007;14:328–30.PubMedCrossRef

12.

Hayashi K, Matsuo T, Kurihara M, et al. Skull metastasis of hepatocellular carcinoma associated with acute epidural haematoma:a case report. Surg Neurol. 2000;53:379–82.PubMedCrossRef

13.

Nakagawa Y, Yoshino E, Suzuki K, et al. Spontaneous epidural haematoma from a hepatocellular carcinoma metastasis to the skull. Neurol Med Chir (Tokyo). 1992;32:300–2.CrossRef

Title: Solitary scalp metastasis – a rare presentation of hepatocellular carcinoma
Authors: Duminda Subasinghe
Chathuranga Tisara Keppetiyagama
Hemantha Sudasinghe
Saman Wadanamby
Niranthi Perera
Sivasuriya Sivaganesh
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: Annals of Surgical Innovation and Research / Issue 1/2015
Electronic ISSN: 1750-1164
DOI: https://doi.org/10.1186/s13022-015-0013-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Solitary scalp metastasis – a rare presentation of hepatocellular carcinoma

Abstract

Introduction

Case presentation

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Case presentation

Conclusion

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