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Obesity Surgery

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Open Access 19-02-2024 | Sleeve Gastrectomy | Original Contributions

The Effects of Sleeve Gastrectomy on the Appetitive Domain of Taste Using the Progressive Ratio Task

Authors: Noura K. Althukair, Ghalia N. Abdeen, Carel W. le Roux, Alex D. Miras, Aayed R. Alqahtani

Published in: Obesity Surgery | Issue 4/2024

Abstract

Introduction

Sleeve gastrectomy (SG) is an effective treatment for obesity in adolescents. The underlying weight loss mechanism may impact the peripheral and central gustatory system along with reward circuits in the brain. This study aims to assess changes in appetitive behavior in short-, medium-, and long-term follow-up.

Methods

In this prospective observational study, a total of 8 adolescents with obesity who underwent SG and 9 comparator unoperated participants were studied. Appetitive behaviour towards fat and sweet taste stimuli was assessed using the Progressive Ratio Task (PRT) over a 6 year period.

Results

Mean body mass index (BMI) of the surgical patients dropped from 51.5 ± 2.8 kg/m² to 31.4 ± 1.9 and 30.9 ± 2.3 kg/m² at 1 and 6 years follow-up, respectively. (p < 0.001). The median (interquartile range) total rewards earned during the PRT was 6 (5–7) pre-surgery, 5 (3–6) after one year and 4 (2–4) after six years from surgery (p = 0.007).

Conclusion

SG reduced appetitive behaviour at 1 year with maintained the benefit over 6 years as measured by the progressive ratio task.

Graphical Abstract

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Title: The Effects of Sleeve Gastrectomy on the Appetitive Domain of Taste Using the Progressive Ratio Task
Authors: Noura K. Althukair
Ghalia N. Abdeen
Carel W. le Roux
Alex D. Miras
Aayed R. Alqahtani
Publication date: 19-02-2024
Publisher: Springer US
Keywords: Sleeve Gastrectomy
Obesity
Obesity
Published in: Obesity Surgery / Issue 4/2024
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI: https://doi.org/10.1007/s11695-023-07035-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The Effects of Sleeve Gastrectomy on the Appetitive Domain of Taste Using the Progressive Ratio Task

Abstract

Introduction

Methods

Results

Conclusion

Graphical Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusion

Graphical Abstract

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