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Obesity Surgery
Published in: Obesity Surgery 9/2021

01-09-2021 | Sleeve Gastrectomy | Original Contributions

The Effect of Helicobacter pylori Eradication on Gastric Wall Thickness in Patients Undergoing Laparoscopic Sleeve Gastrectomy

Authors: Anıl Ergin, Hüseyin Çiyiltepe, Aziz Bora Karip, Mehmet Mahir Fersahoğlu, Nuriye Esen Bulut, Ahmet Çakmak, Berk Topaloğlu, Ali Cihan Bilgili, Adnan Somay, İksan Taşdelen, Ümit Akyüz, Kemal Memişoğlu

Published in: Obesity Surgery | Issue 9/2021

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Abstract

Purpose

The most important cause affecting the thickness of the gastric wall other than the tumor is chronic gastritis caused by Helicobacter pylori (Hp), which is most frequently detected in the antrum. This study aims to investigate the effect of bismuth-based treatment (BBT) combined with proton pump inhibitor (PPI) on wall thicknesses measured in the postoperative gastric specimen and early postoperative complications in patients with Hp-positive pre-LSG endoscopic gastric biopsies.

Materials and Methods

The patients who underwent LSG procedure for morbid obesity were divided into three groups as follows: Hp-negative, Hp-positive without eradication treatment, and Hp-positive, and LSG was performed after eradication treatment. Macroscopic and microscopic gastric wall thickness measurements were made at a distance of 1 cm from the proximal surgical margin, from the middle part of the specimen, and 1 cm from the distal surgical margin in the gastric specimen and the results were compared.

Results

A total of 132 patients were included in the study, 44 patients in each group. Microscopically measured antrum mucosal thickness was found to be statistically significantly higher in group 2 compared to other groups (groups 1.15, 1.35, 1.16 mm, respectively, p = 0.000). There was no difference between the groups in terms of early complications such as bleeding, wound site infection, or leakage from the staple line within the first 28 days after surgery.

Conclusion

This study found that LSG had no effect on early complications due to Hp positivity or eradication of Hp.

Key Points

• The presence of HP increases the wall thickness of the gastric antrum mucosa.
• After HP eradication, stomach antrum wall thickness returns to normal.
• HP eradication before LSG reduces the wall thickness of the gastric antrum mucosa.
• It was determined that HP scanning and eradication before LSG had no effect on postoperative complications.

Graphical abstract

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Metadata
Title
The Effect of Helicobacter pylori Eradication on Gastric Wall Thickness in Patients Undergoing Laparoscopic Sleeve Gastrectomy
Authors
Anıl Ergin
Hüseyin Çiyiltepe
Aziz Bora Karip
Mehmet Mahir Fersahoğlu
Nuriye Esen Bulut
Ahmet Çakmak
Berk Topaloğlu
Ali Cihan Bilgili
Adnan Somay
İksan Taşdelen
Ümit Akyüz
Kemal Memişoğlu
Publication date
01-09-2021
Publisher
Springer US
Published in
Obesity Surgery / Issue 9/2021
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-021-05513-8

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