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Current Neurology and Neuroscience Reports

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01-07-2018 | Sleep (M Thorpy and M Billiard, Section Editors)

Sleep in Children with Congenital Malformations of the Central Nervous System

Authors: Jacqueline F. Yates, Matthew M. Troester, David G. Ingram

Published in: Current Neurology and Neuroscience Reports | Issue 7/2018

Abstract

Purpose of Review

Congenital malformations of the central nervous system may be seen in isolation or in association with syndromes that have multiorgan involvement. Among the potential health challenges these children may face, sleep concerns are frequent and may include chronic insomnia, sleep-related breathing disorders, and circadian rhythm disorders.

Recent Findings

In this review, we describe recent research into sleep disorders affecting children with congenital malformations of the CNS including visual impairment, septo-optic dysplasia, agenesis of the corpus callosum, Aicardi syndrome, Chiari malformation, spina bifida, achondroplasia, Joubert syndrome, fetal alcohol spectrum disorders, and congenital Zika syndrome. In many cases, the sleep disturbance can be directly related to observed anatomical differences in the brain (such as in apnea due to Chiari malformation), but in most syndromes, a complete understanding of the underlying pathophysiology connecting the malformation with sleep problem is still being elucidated.

Summary

Our review provides a synthesis of available evidence for clinicians who treat this patient population, in whom appropriate diagnosis and management of sleep problems may improve the quality of life for both patient and caregiver.

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Title: Sleep in Children with Congenital Malformations of the Central Nervous System
Authors: Jacqueline F. Yates
Matthew M. Troester
David G. Ingram
Publication date: 01-07-2018
Publisher: Springer US
Published in: Current Neurology and Neuroscience Reports / Issue 7/2018
Print ISSN: 1528-4042
Electronic ISSN: 1534-6293
DOI: https://doi.org/10.1007/s11910-018-0850-6

At a glance: The STEP trials

Springer Medicine

Sleep in Children with Congenital Malformations of the Central Nervous System

Abstract

Purpose of Review

Recent Findings

Summary

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose of Review

Recent Findings

Summary

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