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Open Access 01-12-2016 | Case report

Skin metastases of cervical cancer: two case reports and review of the literature

Authors: Meryem Benoulaid, Hanan Elkacemi, Imane Bourhafour, Jihane Khalil, Sanaa Elmajjaoui, Basma Khannoussi, Tayeb Kebdani, Noureddine Benjaafar

Published in: Journal of Medical Case Reports | Issue 1/2016

Abstract

Background

Although cervix carcinoma is one of the most common malignancies in women, hematogenous metastases are relatively not common. Cutaneous metastases, in particular, are unusual even at an advanced stage of disease. Their presence is a predictor of poor prognosis.

Case presentation

Case 1: A 63-year-old postmenopausal Moroccan woman was diagnosed as having cervical squamous cell carcinoma. She was treated with radical concurrent chemotherapy and radiation therapy followed by low-dose brachytherapy. Six months after finishing the therapy, multiple skin nodules appeared on her abdomen and chest wall. An excision biopsy was performed and showed metastatic squamous cell carcinoma. Her disease progressed and she died before completing her fourth course of palliative chemotherapy.

Case 2: A 48-year-old Moroccan woman was diagnosed as having cervical squamous cell carcinoma; she was treated with concurrent chemoradiation. Before a planned high-dose brachytherapy, she noticed many nodular lesions on her arms, thighs, and chest wall. An excision biopsy was performed and showed metastatic squamous cell carcinoma. She then underwent a series of imaging examinations, including computed tomography of her chest, abdomen, and pelvis, and a whole body bone scan that showed disseminated disease involving her lungs and bones. She died after two courses of palliative chemotherapy, 2 months after the appearance of the skin lesions.

Conclusion

We report two cases to illustrate a rare localization of metastasis from cervical carcinoma that is highly aggressive requiring early detection and aggressive management.

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Title: Skin metastases of cervical cancer: two case reports and review of the literature
Authors: Meryem Benoulaid
Hanan Elkacemi
Imane Bourhafour
Jihane Khalil
Sanaa Elmajjaoui
Basma Khannoussi
Tayeb Kebdani
Noureddine Benjaafar
Publication date: 01-12-2016
Publisher: BioMed Central
Published in: Journal of Medical Case Reports / Issue 1/2016
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/s13256-016-1042-0

At a glance: The STEP trials

Springer Medicine

Skin metastases of cervical cancer: two case reports and review of the literature

Abstract

Background

Case presentation

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Case presentation

Conclusion

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