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European Journal of Nuclear Medicine and Molecular Imaging

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01-07-2012 | Image of the Month

Skin lesions, elevated serum lipase level and abnormal bone scintigraphy

Authors: Delphine Luyx, Eric Laurent, Myriam Van der Schueren, Jean-Jacques Houben, Sandrine Roland, Fabienne Rickaert, Max Lonneux

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 7/2012

Excerpt

A 60-year-old man was referred for joint and bone pain, and skin lesions on the lower limbs. Bone scintigraphy showed increased tracer uptake in the metacarpal bones and interphalangeal joints of both hands, in the calcaneus and metatarsal bones, and in the right humerus, femur and tibia (a–c). Biological work-up revealed a very high lipase level (3,000 IU/l, normal <60 IU/l) and a normal amylase value. FDG PET/CT detected a large hypermetabolic mass in the tail of the pancreas and liver metastases. It also showed multiple skin hot spots on both legs, corresponding to panniculitis (d, e). Surgery was performed and histopathology revealed an acinar cell carcinoma of the pancreas. …

Klimstra DS, Heffess CS, Oertel JE, Rosai J. Acinar cell carcinoma of the pancreas. A clinicopathological study of 28 cases. Am J Surg Pathol. 1992;16:815–37.PubMedCrossRef

Vasdev V, Bhakuni D, Narayanan K, Jain R. Intramedullary fat necrosis, polyarthritis and panniculitis with pancreatic tumor: a case report. Int J Rheum Dis. 2010;13:e74–8.PubMedCrossRef

Borowicz J, Morrison M, Hogan D, Miller R. Subcutaneous fat necrosis/panniculitis and polyarthritis associated with acinar cell carcinoma of the pancreas: a rare presentation of pancreatitis, panniculitis and polyarthritis syndrome. J Drugs Dermatol. 2010;9:1145–50.PubMed

Ahn BC, Lee J, Suh KJ, Chun KA, Sohn SK, Lee K, et al. Intramedullary fat necrosis of multiple bones associated with pancreatitis. J Nucl Med. 1998;39:1401–4.PubMed

Goluboff N, Cram R, Ramgotra B, Singh A, Wilkinson GW. Polyarthritis and bone lesions complicating traumatic pancreatitis in two children. Can Med Assoc J. 1978;22:924–8.

Title: Skin lesions, elevated serum lipase level and abnormal bone scintigraphy
Authors: Delphine Luyx
Eric Laurent
Myriam Van der Schueren
Jean-Jacques Houben
Sandrine Roland
Fabienne Rickaert
Max Lonneux
Publication date: 01-07-2012
Publisher: Springer-Verlag
Published in: European Journal of Nuclear Medicine and Molecular Imaging / Issue 7/2012
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-012-2098-8

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Skin lesions, elevated serum lipase level and abnormal bone scintigraphy

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